Hasil Pencarian - Jonathan Frew

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  1. 1
    Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

    Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice oleh Jonathan Frew, Haakon Berge Nygaard

    Diterbitkan 2021-04-01
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  2. 2
    Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress

    Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress oleh Stefan Wendt, Sora Johnson, Nicholas L. Weilinger, Christopher Groten, Stefano Sorrentino, Jonathan Frew, Lucy Yang, Hyun B. Choi, Haakon B. Nygaard, Brian A. MacVicar

    Diterbitkan 2022-10-01
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  3. 3
    hiPSC-derived GRN-deficient astrocytes delay spiking activity of developing neurons

    hiPSC-derived GRN-deficient astrocytes delay spiking activity of developing neurons oleh Christopher Lee, Jonathan Frew, Nicholas L. Weilinger, Stefan Wendt, Wenji Cai, Stefano Sorrentino, Xiujuan Wu, Brian A. MacVicar, Stephanie M. Willerth, Haakon B. Nygaard

    Diterbitkan 2023-06-01
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  4. 4
    Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

    Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency oleh Jonathan Frew, Alireza Baradaran-Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns, Fahimeh S. Shidmoossavee, Jason Tan, James B. Jaquith, Karen R. Jansen-West, Francis C. Lynn, Fen-Biao Gao, Leonard Petrucelli, Howard H. Feldman, Ian R. Mackenzie, Michel Roberge, Haakon B. Nygaard

    Diterbitkan 2020-03-01
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