Identifying intragenic functional modules of genomic variations associated with cancer phenotypes by learning representation of association networks by Minsu Kim, Jennifer E. Huffman, Amy Justice, Ian Goethert, Greeshma Agasthya, VA Million Veteran Program, Ioana Danciu

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Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization by Biqi Wang, Jacqueline S. Dron, Yuxuan Wang, Seung Hoan Choi, Jennifer E. Huffman, Kelly Cho, Peter W. F. Wilson, Pradeep Natarajan, Gina M. Peloso

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Comparison of methods for building polygenic scores for diverse populations by Sophia Gunn, Xin Wang, Daniel C. Posner, Kelly Cho, Jennifer E. Huffman, Michael Gaziano, Peter W. Wilson, Yan V. Sun, Gina Peloso, Kathryn L. Lunetta

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Rare coding variants pinpoint genes that control human hematological traits. by Abdou Mousas, Georgios Ntritsos, Ming-Huei Chen, Ci Song, Jennifer E Huffman, Ioanna Tzoulaki, Paul Elliott, Bruce M Psaty, Blood-Cell Consortium, Paul L Auer, Andrew D Johnson, Evangelos Evangelou, Guillaume Lettre, Alexander P Reiner

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Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sexResearch in context by Tamar Sofer, Nuzulul Kurniansyah, Michael Murray, Yuk-Lam Ho, Erik Abner, Tõnu Esko, Jennifer E. Huffman, Kelly Cho, Peter W.F. Wilson, Daniel J. Gottlieb, Andres Metspalu, Lili Milani, Tõnu Esko, Reedik Mägi, Mari Nelis, Georgi Hudjashov

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Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies. by Peter K Joshi, James Prendergast, Ross M Fraser, Jennifer E Huffman, Veronique Vitart, Caroline Hayward, Ruth McQuillan, Dominik Glodzik, Ozren Polašek, Nicholas D Hastie, Igor Rudan, Harry Campbell, Alan F Wright, Chris S Haley, James F Wilson, Pau Navarro

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Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation by Ming-Huei Chen, Lisa R. Yanek, Joshua D. Backman, John D. Eicher, Jennifer E. Huffman, Yoav Ben-Shlomo, Andrew D. Beswick, Laura M. Yerges-Armstrong, Alan R. Shuldiner, Jeffrey R. O’Connell, Rasika A. Mathias, Diane M. Becker, Lewis C. Becker, Joshua P. Lewis, Andrew D. Johnson, Nauder Faraday

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Genetic architecture of heart failure with preserved versus reduced ejection fraction by Jacob Joseph, Chang Liu, Qin Hui, Krishna Aragam, Zeyuan Wang, Brian Charest, Jennifer E. Huffman, Jacob M. Keaton, Todd L. Edwards, Serkalem Demissie, Luc Djousse, Juan P. Casas, J. Michael Gaziano, Kelly Cho, Peter W. F. Wilson, Lawrence S. Phillips, VA Million Veteran Program, Christopher J. O’Donnell, Yan V. Sun

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PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort. by Aeron M Small, Jennifer E Huffman, Derek Klarin, Julie A Lynch, Themistocles Assimes, Scott DuVall, Yan V Sun, Labiba Shere, Pradeep Natarajan, Michael Gaziano, Daniel J Rader, Peter W F Wilson, Philip S Tsao, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, Juan P Casas, Scott M Damrauer, VA Million Veteran Program

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The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function by J. Allen Bennett, Michael A. Mastrangelo, Sara K. Ture, Charles O. Smith, Shannon G. Loelius, Rachel A. Berg, Xu Shi, Ryan M. Burke, Sherry L. Spinelli, Scott J. Cameron, Thomas E. Carey, Paul S. Brookes, Robert E. Gerszten, Maria Sabater-Lleal, Paul S. de Vries, Jennifer E. Huffman, Nicholas L. Smith, Craig N. Morrell, Charles J. Lowenstein

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Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program. by Rose D L Huang, Xuan-Mai T Nguyen, Gina M Peloso, Mark Trinder, Daniel C Posner, Krishna G Aragam, Yuk-Lam Ho, Julie A Lynch, Scott M Damrauer, Kyong-Mi Chang, Philip S Tsao, Pradeep Natarajan, Themistocles Assimes, J Michael Gaziano, Luc Djousse, Kelly Cho, Peter W F Wilson, Jennifer E Huffman, Christopher J O'Donnell, Veterans Affairs’ Million Veteran Program

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Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation. by Gordan Lauc, Abdelkader Essafi, Jennifer E Huffman, Caroline Hayward, Ana Knežević, Jayesh J Kattla, Ozren Polašek, Olga Gornik, Veronique Vitart, Jodie L Abrahams, Maja Pučić, Mislav Novokmet, Irma Redžić, Susan Campbell, Sarah H Wild, Fran Borovečki, Wei Wang, Ivana Kolčić, Lina Zgaga, Ulf Gyllensten, James F Wilson, Alan F Wright, Nicholas D Hastie, Harry Campbell, Pauline M Rudd, Igor Rudan

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Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program by Rose D. L. Huang, Xuan-Mai T. Nguyen, Gina M. Peloso, Mark Trinder, Daniel C. Posner, Krishna G. Aragam, Yuk-Lam Ho, Julie A. Lynch, Scott M. Damrauer, Kyong-Mi Chang, Philip S. Tsao, Pradeep Natarajan, Themistocles Assimes, J. Michael Gaziano, Luc Djousse, Kelly Cho, Peter W. F. Wilson, Jennifer E. Huffman, Christopher J. O’Donnell, on behalf of the Veterans Affairs’ Million Veteran Program

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A general approach for haplotype phasing across the full spectrum of relatedness. by Jared O'Connell, Deepti Gurdasani, Olivier Delaneau, Nicola Pirastu, Sheila Ulivi, Massimiliano Cocca, Michela Traglia, Jie Huang, Jennifer E Huffman, Igor Rudan, Ruth McQuillan, Ross M Fraser, Harry Campbell, Ozren Polasek, Gershim Asiki, Kenneth Ekoru, Caroline Hayward, Alan F Wright, Veronique Vitart, Pau Navarro, Jean-Francois Zagury, James F Wilson, Daniela Toniolo, Paolo Gasparini, Nicole Soranzo, Manjinder S Sandhu, Jonathan Marchini

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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program by Sridharan Raghavan, Jie Huang, Catherine Tcheandjieu, Jennifer E. Huffman, Elizabeth Litkowski, Chang Liu, Yuk-Lam A. Ho, Haley Hunter-Zinck, Hongyu Zhao, Eirini Marouli, Kari E. North, the VA Million Veteran Program, Ethan Lange, Leslie A. Lange, Benjamin F. Voight, J. Michael Gaziano, Saiju Pyarajan, Elizabeth R. Hauser, Philip S. Tsao, Peter W. F. Wilson, Kyong-Mi Chang, Kelly Cho, Christopher J. O’Donnell, Yan V. Sun, Themistocles L. Assimes

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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program. by Sridharan Raghavan, Jie Huang, Catherine Tcheandjieu, Jennifer E Huffman, Elizabeth Litkowski, Chang Liu, Yuk-Lam A Ho, Haley Hunter-Zinck, Hongyu Zhao, Eirini Marouli, Kari E North, VA Million Veteran Program, Ethan Lange, Leslie A Lange, Benjamin F Voight, J Michael Gaziano, Saiju Pyarajan, Elizabeth R Hauser, Philip S Tsao, Peter W F Wilson, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, Yan V Sun, Themistocles L Assimes

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Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program. by Allison E Ashley-Koch, Nathan A Kimbrel, Xue J Qin, Jennifer H Lindquist, Melanie E Garrett, Michelle F Dennis, Lauren P Hair, Jennifer E Huffman, Daniel A Jacobson, Ravi K Madduri, Hilary Coon, Anna R Docherty, Jooeun Kang, Niamh Mullins, Douglas M Ruderfer, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, International Suicide Genetics Consortium, Philip D Harvey, Benjamin H McMahon, David W Oslin, Elizabeth R Hauser, Michael A Hauser, Jean C Beckham

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Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program. by Rebecca J Song, Yuk-Lam Ho, Petra Schubert, Yojin Park, Daniel Posner, Emily M Lord, Lauren Costa, Hanna Gerlovin, Katherine E Kurgansky, Tori Anglin-Foote, Scott DuVall, Jennifer E Huffman, Saiju Pyarajan, Jean C Beckham, Kyong-Mi Chang, Katherine P Liao, Luc Djousse, David R Gagnon, Stacey B Whitbourne, Rachel Ramoni, Sumitra Muralidhar, Philip S Tsao, Christopher J O'Donnell, John Michael Gaziano, Juan P Casas, Kelly Cho, VA Million Veteran Program COVID-19 Science Initiative

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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels by Adrienne Tin, Yong Li, Jennifer A. Brody, Teresa Nutile, Audrey Y. Chu, Jennifer E. Huffman, Qiong Yang, Ming-Huei Chen, Cassianne Robinson-Cohen, Aurélien Macé, Jun Liu, Ayşe Demirkan, Rossella Sorice, Sanaz Sedaghat, Melody Swen, Bing Yu, Sahar Ghasemi, Alexanda Teumer, Peter Vollenweider, Marina Ciullo, Meng Li, André G. Uitterlinden, Robert Kraaij, Najaf Amin, Jeroen van Rooij, Zoltán Kutalik, Abbas Dehghan, Barbara McKnight, Cornelia M. van Duijn, Alanna Morrison, Bruce M. Psaty, Eric Boerwinkle, Caroline S. Fox, Owen M. Woodward, Anna Köttgen

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Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure by Danielle Rasooly, Gina M. Peloso, Alexandre C. Pereira, Hesam Dashti, Claudia Giambartolomei, Eleanor Wheeler, Nay Aung, Brian R. Ferolito, Maik Pietzner, Eric H. Farber-Eger, Quinn Stanton Wells, Nicole M. Kosik, Liam Gaziano, Daniel C. Posner, A. Patrícia Bento, Qin Hui, Chang Liu, Krishna Aragam, Zeyuan Wang, Brian Charest, Jennifer E. Huffman, Peter W. F. Wilson, Lawrence S. Phillips, John Whittaker, Patricia B. Munroe, Steffen E. Petersen, Kelly Cho, Andrew R. Leach, María Paula Magariños, John Michael Gaziano, VA Million Veteran Program, Claudia Langenberg, Yan V. Sun, Jacob Joseph, Juan P. Casas

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