Hasil Pencarian - Jasper Dingemanse

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  1. 1
    Drug Development for Pediatric Populations: Regulatory Aspects

    Drug Development for Pediatric Populations: Regulatory Aspects oleh Jochen Zisowsky, Jasper Dingemanse, Andreas Krause

    Diterbitkan 2010-11-01
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  2. 2
    Cardiodynamic Interactions between Two S1P<sub>1</sub> Receptor Modulators in an Experimental Clinical Setting: Different Pharmacokinetic Properties as an Opportunity to Mitigate First-Dose Heart Rate Effects

    Cardiodynamic Interactions between Two S1P<sub>1</sub> Receptor Modulators in an Experimental Clinical Setting: Different Pharmacokinetic Properties as an Opportunity to Mitigate F... oleh Pierre-Eric Juif, Mike Ufer, Jasper Dingemanse

    Diterbitkan 2019-07-01
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  3. 3
    Clinical Pharmacology of Clazosentan, a Selective Endothelin A Receptor Antagonist for the Prevention and Treatment of aSAH-Related Cerebral Vasospasm

    Clinical Pharmacology of Clazosentan, a Selective Endothelin A Receptor Antagonist for the Prevention and Treatment of aSAH-Related Cerebral Vasospasm oleh Pierre-Eric Juif, Jasper Dingemanse, Mike Ufer

    Diterbitkan 2021-02-01
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  4. 4
    Investigation of the effect of the dual orexin receptor antagonist almorexant on ophthalmological, spermatogenic, and hormonal variables in healthy male subjects

    Investigation of the effect of the dual orexin receptor antagonist almorexant on ophthalmological, spermatogenic, and hormonal variables in healthy male subjects oleh Jasper Dingemanse, Pascal Charef, Jed Black, Chris Gouws

    Diterbitkan 2021-01-01
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  5. 5
    Pharmacokinetics of daridorexant, a dual orexin receptor antagonist, are not affected by renal impairment

    Pharmacokinetics of daridorexant, a dual orexin receptor antagonist, are not affected by renal impairment oleh Benjamin Berger, Clemens Muehlan, Gernot Klein, Jasper Dingemanse

    Diterbitkan 2021-11-01
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  6. 6
    Lack of Effect of Cenerimod, a Selective S1P<sub>1</sub> Receptor Modulator, on the Pharmacokinetics of a Combined Oral Contraceptive

    Lack of Effect of Cenerimod, a Selective S1P<sub>1</sub> Receptor Modulator, on the Pharmacokinetics of a Combined Oral Contraceptive oleh Pierre-Eric Juif, Markus S. Mueller, Hakim Charfi, Jasper Dingemanse

    Diterbitkan 2022-11-01
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  7. 7
    Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P1R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects

    Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P1R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects oleh Pierre‐Eric Juif, Jasper Dingemanse, Peter Winkle, Mike Ufer

    Diterbitkan 2021-01-01
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  8. 8
    Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y12 receptor between selatogrel and oral P2Y12 antagonists

    Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y12 receptor between selatogrel and oral P2Y12 antagonists oleh Andrea Henrich, Christian Hove Claussen, Jasper Dingemanse, Andreas Krause

    Diterbitkan 2021-07-01
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  9. 9
    Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects

    Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects oleh Isabelle Zenklusen, Jasper Dingemanse, Christian Reh, Martine Gehin, Priska Kaufmann

    Diterbitkan 2024-03-01
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  10. 10
    Population pharmacokinetic modeling of daridorexant, a novel dual orexin receptor antagonist

    Population pharmacokinetic modeling of daridorexant, a novel dual orexin receptor antagonist oleh Andreas Krause, Dominik Lott, Janneke M. Brussee, Clemens Muehlan, Jasper Dingemanse

    Diterbitkan 2023-01-01
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  11. 11
    Influence of Rifampin‐Mediated Organic Anion‐Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan

    Influence of Rifampin‐Mediated Organic Anion‐Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan oleh Pierre‐Eric Juif, Christine Voors‐Pette, Mike Ufer, Peter Dogterom, Jasper Dingemanse

    Diterbitkan 2019-09-01
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  12. 12
    Effect of nivasorexant (ACT‐539313), a selective orexin‐1‐receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects

    Effect of nivasorexant (ACT‐539313), a selective orexin‐1‐receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in health... oleh Benjamin Berger, Priska Kaufmann, Matthias Berse, Alexander Treiber, Nathalie Grignaschi, Jasper Dingemanse

    Diterbitkan 2023-10-01
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  13. 13
    Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment

    Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment oleh Magda S. C. Fontes, Jasper Dingemanse, Atef Halabi, Monika Tomaszewska-Kiecana, Patricia N. Sidharta

    Diterbitkan 2022-11-01
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  14. 14
    Mind the Gap: Model-Based Switching from Selatogrel to Maintenance Therapy with Oral P2Y12 Receptor Antagonists

    Mind the Gap: Model-Based Switching from Selatogrel to Maintenance Therapy with Oral P2Y12 Receptor Antagonists oleh Chih-hsuan Hsin, Jasper Dingemanse, Andrea Henrich, Corine Bernaud, Martine Gehin, Andreas Krause

    Diterbitkan 2023-09-01
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  15. 15
    Effect of Rifampin‐Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel

    Effect of Rifampin‐Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel oleh Uta Schilling, Jasper Dingemanse, Christine Voors‐Pette, Christel Romeijn, Peter Dogterom, Mike Ufer

    Diterbitkan 2020-09-01
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  16. 16
    Assessment of Target Engagement in a First‐in‐Human Trial with Sinbaglustat, an Iminosugar to Treat Lysosomal Storage Disorders

    Assessment of Target Engagement in a First‐in‐Human Trial with Sinbaglustat, an Iminosugar to Treat Lysosomal Storage Disorders oleh Martine Gehin, Meggane Melchior, Richard W.D. Welford, Patricia N. Sidharta, Jasper Dingemanse

    Diterbitkan 2021-03-01
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  17. 17
    The effect of itraconazole, a strong CYP3A4 inhibitor, on the pharmacokinetics of the first‐in‐class ACKR3/CXCR7 antagonist, ACT‐1004‐1239

    The effect of itraconazole, a strong CYP3A4 inhibitor, on the pharmacokinetics of the first‐in‐class ACKR3/CXCR7 antagonist, ACT‐1004‐1239 oleh Christine Huynh, Jasper Dingemanse, Henriette E. Meyer zu Schwabedissen, Marlene Fonseca, Patricia N. Sidharta

    Diterbitkan 2024-07-01
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  18. 18
    The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects

    The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects oleh Markus S. Mueller, Patricia N. Sidharta, Christine Voors-Pette, Borje Darpo, Hongqi Xue, Jasper Dingemanse

    Diterbitkan 2020-10-01
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  19. 19
    Influence of hepatic impairment on the pharmacokinetics and pharmacodynamics of the P2Y12 receptor antagonist selatogrel

    Influence of hepatic impairment on the pharmacokinetics and pharmacodynamics of the P2Y12 receptor antagonist selatogrel oleh Uta Schilling, Chih‐Hsuan Hsin, Stephane Delahaye, Andreas Krause, Hauke Wuelfrath, Atef Halabi, Jasper Dingemanse

    Diterbitkan 2022-08-01
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  20. 20
    Evaluation of the cytochrome P450 2C19 and 3A4 inhibition potential of the complement factor 5a receptor 1 antagonist ACT‐1014‐6470 in vitro and in vivo

    Evaluation of the cytochrome P450 2C19 and 3A4 inhibition potential of the complement factor 5a receptor 1 antagonist ACT‐1014‐6470 in vitro and in vivo oleh Marion Anliker‐Ort, Jasper Dingemanse, Stephane Delahaye, Luboš Janů, John van denAnker, Benjamin Berger, Priska Kaufmann

    Diterbitkan 2023-07-01
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