Search Results - Jann N. Sarkaria

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  1. 1
    Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model

    Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model by Mai T. Ngo, Jann N. Sarkaria, Brendan A.C. Harley

    Published 2022-11-01
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  2. 2
    Editorial: Targeted Therapies for Glioblastoma: A Critical Appraisal

    Editorial: Targeted Therapies for Glioblastoma: A Critical Appraisal by Shiv K. Gupta, Sani H. Kizilbash, David J. Daniels, Jann N. Sarkaria

    Published 2019-11-01
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  3. 3
    Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain.

    Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain. by Gobinda Sarkar, Geoffry L Curran, Jann N Sarkaria, Val J Lowe, Robert B Jenkins

    Published 2014-01-01
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  4. 4
    The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma

    The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma by Rodrigo Javier, Wenxia Wang, Michael Drumm, Kathleen McCortney, Jann N. Sarkaria, Craig Horbinski

    Published 2022-01-01
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  5. 5
    The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma.

    The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma. by Rodrigo Javier, Wenxia Wang, Michael Drumm, Kathleen McCortney, Jann N Sarkaria, Craig Horbinski

    Published 2022-01-01
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  6. 6
    MDM2 Inhibition in the Treatment of Glioblastoma: From Concept to Clinical Investigation

    MDM2 Inhibition in the Treatment of Glioblastoma: From Concept to Clinical Investigation by Karolina I. Pellot Ortiz, Julian S. Rechberger, Leo F. Nonnenbroich, David J. Daniels, Jann N. Sarkaria

    Published 2023-07-01
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  7. 7
    Differential H<sub>2</sub>O<sub>2</sub> Metabolism among Glioblastoma Subtypes Confers Variable Responses to Pharmacological Ascorbate Therapy Combined with Chemoradiation

    Differential H<sub>2</sub>O<sub>2</sub> Metabolism among Glioblastoma Subtypes Confers Variable Responses to Pharmacological Ascorbate Therapy Combined with Chemoradiation by Amira Zaher, Kranti A. Mapuskar, Jann N. Sarkaria, Douglas R. Spitz, Michael S. Petronek, Bryan G. Allen

    Published 2023-12-01
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  8. 8
    IL-13Rα2 Status Predicts GB-13 (IL13.E13K-PE4E) Efficacy in High-Grade Glioma

    IL-13Rα2 Status Predicts GB-13 (IL13.E13K-PE4E) Efficacy in High-Grade Glioma by Julian S. Rechberger, Kendra A. Porath, Liang Zhang, Cody L. Nesvick, Randy S. Schrecengost, Jann N. Sarkaria, David J. Daniels

    Published 2022-04-01
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  9. 9
    Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors

    Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors by Jessica I. Griffith, Sneha Rathi, Wenqiu Zhang, Wenjuan Zhang, Lester R. Drewes, Jann N. Sarkaria, William F. Elmquist

    Published 2020-12-01
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  10. 10
    The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion

    The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion by Anna M. Jermakowicz, Matthew J. Rybin, Robert K. Suter, Jann N. Sarkaria, Zane Zeier, Yangbo Feng, Nagi G. Ayad

    Published 2021-12-01
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  11. 11
    H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers

    H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers by Dong Fang, Haiyun Gan, Liang Cheng, Jeong-Heon Lee, Hui Zhou, Jann N Sarkaria, David J Daniels, Zhiguo Zhang

    Published 2018-06-01
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  12. 12
    Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells.

    Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells. by Zachary D Nagel, Andrew A Beharry, Patrizia Mazzucato, Gaspar J Kitange, Jann N Sarkaria, Eric T Kool, Leona D Samson

    Published 2019-01-01
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  13. 13
    Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype.

    Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. by Laura J Lewis-Tuffin, Fausto Rodriguez, Caterina Giannini, Bernd Scheithauer, Brian M Necela, Jann N Sarkaria, Panos Z Anastasiadis

    Published 2010-10-01
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  14. 14
    IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling

    IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling by Claudia R. Oliva, Brian Halloran, Anita B. Hjelmeland, Ana Vazquez, Shannon M. Bailey, Jann N. Sarkaria, Corinne E. Griguer

    Published 2018-09-01
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  15. 15
    Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells

    Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells by Ravi D. Rao, Ann C. Mladek, Jeffrey D. Lamont, Jennie M. Goble, Charles Erlichman, C. David James, Jann N. Sarkaria

    Published 2005-10-01
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  16. 16
    Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.

    Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition. by R Marisol Herrera-Perez, Sherry L Voytik-Harbin, Jann N Sarkaria, Karen E Pollok, Melissa L Fishel, Jenna L Rickus

    Published 2018-01-01
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  17. 17
    Quantifying Glioblastoma Drug Response Dynamics Incorporating Treatment Sensitivity and Blood Brain Barrier Penetrance From Experimental Data

    Quantifying Glioblastoma Drug Response Dynamics Incorporating Treatment Sensitivity and Blood Brain Barrier Penetrance From Experimental Data by Susan Christine Massey, Javier C. Urcuyo, Bianca Maria Marin, Jann N. Sarkaria, Kristin R. Swanson, Kristin R. Swanson, Kristin R. Swanson

    Published 2020-08-01
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  18. 18
    Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model

    Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model by Jee-Wei Emily Chen, Jan Lumibao, Sarah Leary, Jann N. Sarkaria, Andrew J. Steelman, H. Rex Gaskins, Brendan A. C. Harley

    Published 2020-11-01
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  19. 19
    A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma

    A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma by Wan-Hsin Lin, Ryan W. Feathers, Lisa M. Cooper, Laura J. Lewis-Tuffin, Jiaxiang Chen, Jann N. Sarkaria, Panos Z. Anastasiadis

    Published 2023-07-01
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  20. 20
    Influence of Hyaluronic Acid Transitions in Tumor Microenvironment on Glioblastoma Malignancy and Invasive Behavior

    Influence of Hyaluronic Acid Transitions in Tumor Microenvironment on Glioblastoma Malignancy and Invasive Behavior by Jee-Wei E. Chen, Sara Pedron, Peter Shyu, Yuhang Hu, Jann N. Sarkaria, Brendan A. C. Harley, Brendan A. C. Harley

    Published 2018-06-01
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