Hasil Pencarian - J. Fernando Díaz

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  1. 1
    Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

    Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate oleh Fabienne Zdenka Gaugaz, Andrea Chicca, Mariano Redondo-Horcajo, Isabel Barasoain, J. Fernando Díaz, Karl-Heinz Altmann

    Diterbitkan 2019-03-01
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  2. 2
    Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin

    Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin oleh Ashwani Sharma, Gonzalo Sáez-Calvo, Natacha Olieric, Francisco de Asís Balaguer, Isabel Barasoain, Clemens Lamberth, J. Fernando Díaz, Michel O. Steinmetz

    Diterbitkan 2017-06-01
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  3. 3
    Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)

    Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) oleh Andrea Jantsch, Lidia Nieto, Jürg Gertsch, Javier Rodríguez-Salarichs, Ruth Matesanz, Jesús Jiménez-Barbero, J. Fernando Díaz, Ángeles Canales, Karl-Heinz Altmann

    Diterbitkan 2016-08-01
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  4. 4
    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin oleh Grégory Menchon, Andrea E. Prota, Daniel Lucena-Agell, Pascal Bucher, Rolf Jansen, Herbert Irschik, Rolf Müller, Ian Paterson, J. Fernando Díaz, Karl-Heinz Altmann, Michel O. Steinmetz

    Diterbitkan 2018-05-01
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  5. 5
    Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells

    Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells oleh Jessica Nayelli Sánchez-Carranza, Mariano Redondo-Horcajo, Isabel Barasoain, Ever Angel Escobar-Aguilar, César Millán-Pacheco, Laura Alvarez, Enrique Salas Vidal, J. Fernando Diaz, Leticia Gonzalez-Maya

    Diterbitkan 2023-11-01
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  6. 6
    Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity

    Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity oleh Cristina Gallego-Páramo, Cristina Gallego-Páramo, Noelia Hernández-Ortiz, Rubén M. Buey, Palma Rico-Lastres, Palma Rico-Lastres, Guadalupe García, Guadalupe García, J. Fernando Díaz, Pedro García, Pedro García, Margarita Menéndez, Margarita Menéndez

    Diterbitkan 2021-10-01
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  7. 7
    Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells

    Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells oleh Chiara Trigili, Isabel Barasoain, Pedro A. Sánchez-Murcia, Katja Bargsten, Mariano Redondo-Horcajo, Aurora Nogales, Nicola M. Gardner, Arndt Meyer, Guy J. Naylor, Elena Gómez-Rubio, Federico Gago, Michel O. Steinmetz, Ian Paterson, Andrea E. Prota, J. Fernando Díaz

    Diterbitkan 2016-12-01
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  8. 8
    Structural insight into the stabilization of microtubules by taxanes

    Structural insight into the stabilization of microtubules by taxanes oleh Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz

    Diterbitkan 2023-03-01
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  9. 9
    Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

    Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands oleh Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan Francisco Giménez-Abián, April L. Risinger, Erik J. Sorensen, Christopher D. Vanderwal, Karl-Heinz Altmann, Susan L. Mooberry, Michel O. Steinmetz, María Ángela Oliva, Andrea E. Prota, J. Fernando Díaz

    Diterbitkan 2019-03-01
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  10. 10
    Structural model for differential cap maturation at growing microtubule ends

    Structural model for differential cap maturation at growing microtubule ends oleh Juan Estévez-Gallego, Fernando Josa-Prado, Siou Ku, Ruben M Buey, Francisco A Balaguer, Andrea E Prota, Daniel Lucena-Agell, Christina Kamma-Lorger, Toshiki Yagi, Hiroyuki Iwamoto, Laurence Duchesne, Isabel Barasoain, Michel O Steinmetz, Denis Chrétien, Shinji Kamimura, J Fernando Díaz, Maria A Oliva

    Diterbitkan 2020-03-01
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  11. 11
    Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

    Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention oleh Thomas Bohnacker, Andrea E. Prota, Florent Beaufils, John E. Burke, Anna Melone, Alison J. Inglis, Denise Rageot, Alexander M. Sele, Vladimir Cmiljanovic, Natasa Cmiljanovic, Katja Bargsten, Amol Aher, Anna Akhmanova, J. Fernando Díaz, Doriano Fabbro, Marketa Zvelebil, Roger L. Williams, Michel O. Steinmetz, Matthias P. Wymann

    Diterbitkan 2017-03-01
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