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  1. 1
    717 A phase 1/2 study of AU-007, a monoclonal antibody (mAb) that binds to IL-2 and inhibits CD25 binding, in patients with advanced solid tumors: interim results from dose escalation

    717 A phase 1/2 study of AU-007, a monoclonal antibody (mAb) that binds to IL-2 and inhibits CD25 binding, in patients with advanced solid tumors: interim results from dose escalat... oleh Andrew Haydon, John Powderly, Timothy Wyant, James Vasselli, Drew Rasco, Meredith McKean, Elizabeth Ahern, Sophia Frentzas, Andrew Weickhardt, Inbar Amit, Aron Knickerbocker, Yanay Ofran, Paul de Souza, Jenny Tang, Lori Richards

    Diterbitkan 2023-11-01
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  2. 2
    704 The computationally designed human antibody, AU-007, mediates human immune activation by endogenous IL-2, while uniquely breaking the IL-2 auto-inhibitory loop and preventing Treg expansion

    704 The computationally designed human antibody, AU-007, mediates human immune activation by endogenous IL-2, while uniquely breaking the IL-2 auto-inhibitory loop and preventing T... oleh Timothy Wyant, James Vasselli, Inbar Amit, Itay Levin, Natali Levitan, Reut Barak, May Ben-Mayor, Olga Bluvshtein, Noam Grossman, Yehezkel Sasson, Guy Nimrod, Michael Zehnin, Sharon Fischman, Marek Štrajbl, Liron Danielpur, Aron Knickerbocker, Yanay Ofran

    Diterbitkan 2021-11-01
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