Hasil Pencarian - Hartmut Koeppen

  • Menampilkan 1 - 18 hasil dari 18
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  1. 1
    MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

    MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation oleh Tom T. Chen, Ellen Filvaroff, Jing Peng, Scot Marsters, Adrian Jubb, Hartmut Koeppen, Mark Merchant, Avi Ashkenazi

    Diterbitkan 2015-05-01
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  2. 2
    High cell-surface density of HER2 deforms cell membranes

    High cell-surface density of HER2 deforms cell membranes oleh Inhee Chung, Mike Reichelt, Lily Shao, Robert W. Akita, Hartmut Koeppen, Linda Rangell, Gabriele Schaefer, Ira Mellman, Mark X. Sliwkowski

    Diterbitkan 2016-09-01
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  3. 3
    MET gene copy number alterations and expression of MET and hepatocyte growth factor are potential biomarkers in angiosarcomas and undifferentiated pleomorphic sarcomas.

    MET gene copy number alterations and expression of MET and hepatocyte growth factor are potential biomarkers in angiosarcomas and undifferentiated pleomorphic sarcomas. oleh Katja Schmitz, Hartmut Koeppen, Elke Binot, Jana Fassunke, Helen Künstlinger, Michaela A Ihle, Carina Heydt, Eva Wardelmann, Reinhard Büttner, Sabine Merkelbach-Bruse, Josef Rüschoff, Hans-Ulrich Schildhaus

    Diterbitkan 2015-01-01
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  4. 4
    TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including glioma.

    TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including glioma. oleh Kui Lin, James R Taylor, Thomas D Wu, Johnny Gutierrez, J Michael Elliott, Jean-Michel Vernes, Hartmut Koeppen, Heidi S Phillips, Frederic J de Sauvage, Y Gloria Meng

    Diterbitkan 2011-01-01
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  5. 5
    601 Identification of non-squamous NSCLC molecular subtypes and association with outcomes in the phase 3 IMpower150 study of 1L atezolizumab ± bevacizumab + carboplatin-paclitaxel in metastatic NSCLC

    601 Identification of non-squamous NSCLC molecular subtypes and association with outcomes in the phase 3 IMpower150 study of 1L atezolizumab ± bevacizumab + carboplatin-paclitaxel... oleh Aditi Qamra, Hartmut Koeppen, Fabrice Barlesi, Federico Cappuzzo, Martin Reck, Mark A Socinski, Marcus Ballinger, Robert M Jotte, Barzin Nabet, Minu K Srivastava, Soren Muller, Tianshi Lu, Howard West, Habib Hamidi, Assaf Amitai, David S Shames

    Diterbitkan 2023-11-01
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  6. 6
    Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.

    Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers. oleh Erica B Schleifman, Rupal Desai, Jill M Spoerke, Yuanyuan Xiao, Cheryl Wong, Ilma Abbas, Carol O'Brien, Rajesh Patel, Teiko Sumiyoshi, Ling Fu, Rachel N Tam, Hartmut Koeppen, Timothy R Wilson, Rajiv Raja, Garret M Hampton, Mark R Lackner

    Diterbitkan 2014-01-01
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  7. 7
    Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

    Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α oleh Adrien Le Thomas, Elena Ferri, Scot Marsters, Jonathan M. Harnoss, David A. Lawrence, Iratxe Zuazo-Gaztelu, Zora Modrusan, Sara Chan, Margaret Solon, Cécile Chalouni, Weihan Li, Hartmut Koeppen, Joachim Rudolph, Weiru Wang, Thomas D. Wu, Peter Walter, Avi Ashkenazi

    Diterbitkan 2021-12-01
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  8. 8
    Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer

    Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer oleh Mélanie Desbois, Akshata R. Udyavar, Lisa Ryner, Cleopatra Kozlowski, Yinghui Guan, Milena Dürrbaum, Shan Lu, Jean-Philippe Fortin, Hartmut Koeppen, James Ziai, Ching-Wei Chang, Shilpa Keerthivasan, Marie Plante, Richard Bourgon, Carlos Bais, Priti Hegde, Anneleen Daemen, Shannon Turley, Yulei Wang

    Diterbitkan 2020-11-01
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  9. 9
    Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

    Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice oleh Janet Lau, Jeanne Cheung, Armando Navarro, Steve Lianoglou, Benjamin Haley, Klara Totpal, Laura Sanders, Hartmut Koeppen, Patrick Caplazi, Jacqueline McBride, Henry Chiu, Rebecca Hong, Jane Grogan, Vincent Javinal, Robert Yauch, Bryan Irving, Marcia Belvin, Ira Mellman, Jeong M. Kim, Maike Schmidt

    Diterbitkan 2017-02-01
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  10. 10
    606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy

    606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy oleh Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin

    Diterbitkan 2023-11-01
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  11. 11
    Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma

    Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma oleh Jeffrey J. Wallin, Johanna C. Bendell, Roel Funke, Mario Sznol, Konstanty Korski, Suzanne Jones, Genevive Hernandez, James Mier, Xian He, F. Stephen Hodi, Mitchell Denker, Vincent Leveque, Marta Cañamero, Galina Babitski, Hartmut Koeppen, James Ziai, Neeraj Sharma, Fabien Gaire, Daniel S. Chen, Daniel Waterkamp, Priti S. Hegde, David F. McDermott

    Diterbitkan 2016-08-01
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  12. 12
    Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors

    Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors oleh Kristin M. Zimmerman Savill, Brian B. Lee, Jason Oeh, Jie Lin, Eva Lin, Wei-Jen Chung, Amy Young, Wennie Chen, Monika Miś, Kathryn Mesh, Jeffrey Eastham, Florian Gnad, Zhaoshi Jiang, Eric W. Stawiski, Benjamin Haley, Anneleen Daemen, Xiaojing Wang, Hartmut Koeppen, Zora Modrusan, Scott E. Martin, Deepak Sampath, Kui Lin

    Diterbitkan 2022-04-01
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  13. 13
    Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.

    Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors. oleh Mark Merchant, John Moffat, Gabriele Schaefer, Jocelyn Chan, Xi Wang, Christine Orr, Jason Cheng, Thomas Hunsaker, Lily Shao, Stephanie J Wang, Marie-Claire Wagle, Eva Lin, Peter M Haverty, Sheerin Shahidi-Latham, Hai Ngu, Margaret Solon, Jeffrey Eastham-Anderson, Hartmut Koeppen, Shih-Min A Huang, Jacob Schwarz, Marcia Belvin, Daniel Kirouac, Melissa R Junttila

    Diterbitkan 2017-01-01
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  14. 14
    Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.

    Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors. oleh Mark Merchant, John Moffat, Gabriele Schaefer, Jocelyn Chan, Xi Wang, Christine Orr, Jason Cheng, Thomas Hunsaker, Lily Shao, Stephanie J Wang, Marie-Claire Wagle, Eva Lin, Peter M Haverty, Sheerin Shahidi-Latham, Hai Ngu, Margaret Solon, Jeffrey Eastham-Anderson, Hartmut Koeppen, Shih-Min A Huang, Jacob Schwarz, Marcia Belvin, Daniel Kirouac, Melissa R Junttila

    Diterbitkan 2018-01-01
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  15. 15
    CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials

    CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials oleh Neil H. Segal, Ignacio Melero, Victor Moreno, Neeltje Steeghs, Aurelien Marabelle, Kristoffer Rohrberg, Maria E. Rodriguez-Ruiz, Joseph P. Eder, Cathy Eng, Gulam A. Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C. Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H. Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés

    Diterbitkan 2024-05-01
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  16. 16
    Multimodal Microvascular Imaging Reveals that Selective Inhibition of Class I PI3K Is Sufficient to Induce an Antivascular Response

    Multimodal Microvascular Imaging Reveals that Selective Inhibition of Class I PI3K Is Sufficient to Induce an Antivascular Response oleh Deepak Sampath, Jason Oeh, Shelby K. Wyatt, Tim C. Cao, Hartmut Koeppen, Jeffrey Eastham-Anderson, Liliane Robillard, Calvin C.K. Ho, Jed Ross, Guanglei Zhuang, Hani Bou Reslan, Philip Vitorino, Kai H. Barck, Sharon E. Ungersma, Jean Michel Vernes, Maresa Caunt, Nick Van Bruggen, Weilan Ye, Ulka Vijapurkar, Yu-Ju Gloria Meng, Napoleone Ferrara, Lori S. Friedman, Richard A.D. Carano

    Diterbitkan 2013-07-01
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  17. 17
    Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

    Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers oleh Jennifer Cantley, Xiaofen Ye, Emma Rousseau, Tom Januario, Brian D. Hamman, Christopher M. Rose, Tommy K. Cheung, Trent Hinkle, Leofal Soto, Connor Quinn, Alicia Harbin, Elizabeth Bortolon, Xin Chen, Roy Haskell, Eva Lin, Shang-Fan Yu, Geoff Del Rosario, Emily Chan, Debra Dunlap, Hartmut Koeppen, Scott Martin, Mark Merchant, Matt Grimmer, Fabio Broccatelli, Jing Wang, Jennifer Pizzano, Peter S. Dragovich, Michael Berlin, Robert L. Yauch

    Diterbitkan 2022-11-01
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  18. 18
    Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade

    Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade oleh Marcin Kowanetz, Thomas Powles, Hartmut Koeppen, Jane Grogan, Patrick Caplazi, Ira Mellman, Wei Zou, Sanjeev Mariathasan, Priti S. Hegde, Mark McCleland, Jacqueline McBride, Zora Modrusan, Romain Banchereau, Avantika S. Chitre, Alexis Scherl, Thomas D. Wu, Namrata S. Patil, Patricia de Almeida, Edward E. Kadel, III, Shravan Madireddi, Amelia Au-Yeung, Chikara Takahashi, Ying-Jiun Chen, Rhea Nersesian, Ehab A. El-Gabry, Mark D. Robida, Jeffrey C. Hung, Shadi Toghi Eshgi, W. Rodney Mathews, William E O'Gorman

    Diterbitkan 2021-04-01
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