Hasil Pencarian - Harry T Orr

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  1. 1
    The Ins and Outs of a Polyglutamine Neurodegenerative Disease: Spinocerebellar Ataxia Type 1 (SCA1)

    The Ins and Outs of a Polyglutamine Neurodegenerative Disease: Spinocerebellar Ataxia Type 1 (SCA1) oleh Harry T. Orr

    Diterbitkan 2000-06-01
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  2. 2
    Reduction of Purkinje Cell Pathology in SCA1 Transgenic Mice by p53 Deletion

    Reduction of Purkinje Cell Pathology in SCA1 Transgenic Mice by p53 Deletion oleh Mona D. Shahbazian, Harry T. Orr, Huda Y. Zoghbi

    Diterbitkan 2001-12-01
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  3. 3
    Polarization-sensitive optical coherence tomography reveals gray matter and white matter atrophy in SCA1 mouse models

    Polarization-sensitive optical coherence tomography reveals gray matter and white matter atrophy in SCA1 mouse models oleh Chao J. Liu, Orion Rainwater, H. Brent Clark, Harry T. Orr, Taner Akkin

    Diterbitkan 2018-08-01
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  4. 4
    Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

    Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis. oleh Juan Crespo-Barreto, John D Fryer, Chad A Shaw, Harry T Orr, Huda Y Zoghbi

    Diterbitkan 2010-07-01
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  5. 5
    Antisense RNA Sequences Modulating the Ataxin-1 Message: Molecular Model of Gene Therapy for Spinocerebellar Ataxia Type 1, a Dominant-Acting Unstable Trinucleotide Repeat Disease

    Antisense RNA Sequences Modulating the Ataxin-1 Message: Molecular Model of Gene Therapy for Spinocerebellar Ataxia Type 1, a Dominant-Acting Unstable Trinucleotide Repeat Disease oleh Youxin Gao, Tao Zu, Walter C. Low, Harry T. Orr, R. Scott Mcivor Ph.D.

    Diterbitkan 2008-07-01
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  6. 6
    Expanded ATXN1 alters transcription and calcium signaling in SCA1 human motor neurons differentiated from induced pluripotent stem cells

    Expanded ATXN1 alters transcription and calcium signaling in SCA1 human motor neurons differentiated from induced pluripotent stem cells oleh Carrie Sheeler, Emmanuel Labrada, Lisa Duvick, Leslie M. Thompson, Ying Zhang, Harry T. Orr, Marija Cvetanovic

    Diterbitkan 2024-10-01
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  7. 7
    Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology

    Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology oleh Gülin Öz, Emily Kittelson, Döne Demirgöz, Orion Rainwater, Lynn E. Eberly, Harry T. Orr, H. Brent Clark

    Diterbitkan 2015-02-01
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  8. 8
    Motor neuron degeneration correlates with respiratory dysfunction in SCA1

    Motor neuron degeneration correlates with respiratory dysfunction in SCA1 oleh James P. Orengo, Meike E. van der Heijden, Shuang Hao, Jianrong Tang, Harry T. Orr, Huda Y. Zoghbi

    Diterbitkan 2018-02-01
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  9. 9
    Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model

    Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model oleh James P. Orengo, Larissa Nitschke, Meike E. van der Heijden, Nicholas A. Ciaburri, Harry T. Orr, Huda Y. Zoghbi

    Diterbitkan 2022-04-01
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  10. 10
    Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.

    Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model. oleh Kei Watase, Jennifer R Gatchel, Yaling Sun, Effat Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T Orr, Chad Shaw, Huda Y Zoghbi

    Diterbitkan 2007-05-01
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  11. 11
    Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1

    Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1 oleh Chieh‐Sen Chuang, Jui‐Chih Chang, Bing‐Wen Soong, Sheng‐Fei Chuang, Ta‐Tsung Lin, Wen‐Ling Cheng, Harry T. Orr, Chin‐San Liu

    Diterbitkan 2019-11-01
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  12. 12
    The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways

    The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways oleh Sunyuan Zhang, Nicholas A. Williamson, Lisa Duvick, Alexander Lee, Harry T. Orr, Austin Korlin-Downs, Praseuth Yang, Yee-Foong Mok, David A. Jans, Marie A. Bogoyevitch

    Diterbitkan 2020-07-01
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  13. 13
    Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

    Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla oleh Ivan Tkáč, Tiankai Xie, Nitya Shah, Sarah Larson, Janet M. Dubinsky, Rocio Gomez-Pastor, Hayley S. McLoughlin, Harry T. Orr, Lynn E. Eberly, Lynn E. Eberly, Gülin Öz

    Diterbitkan 2023-10-01
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  14. 14
    Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1

    Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1 oleh Larissa Nitschke, Stephanie L. Coffin, Eder Xhako, Dany B. El-Najjar, James P. Orengo, Elizabeth Alcala, Yanwan Dai, Ying-Wooi Wan, Zhandong Liu, Harry T. Orr, Huda Y. Zoghbi

    Diterbitkan 2021-02-01
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  15. 15
    Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes

    Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes oleh Cristian A Lasagna-Reeves, Maxime WC Rousseaux, Marcos J Guerrero-Munoz, Luis Vilanova-Velez, Jeehye Park, Lauren See, Paymaan Jafar-Nejad, Ronald Richman, Harry T Orr, Rakez Kayed, Huda Y Zoghbi

    Diterbitkan 2015-12-01
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  16. 16
    A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1

    A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1 oleh Cristian A Lasagna-Reeves, Maxime WC Rousseaux, Marcos J Guerrero-Muñoz, Jeehye Park, Paymaan Jafar-Nejad, Ronald Richman, Nan Lu, Urmi Sengupta, Alexandra Litvinchuk, Harry T Orr, Rakez Kayed, Huda Y Zoghbi

    Diterbitkan 2015-05-01
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  17. 17
    Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment

    Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment oleh Brennon O’Callaghan, Bente Hofstra, Hillary P. Handler, Holly B. Kordasiewicz, Tracy Cole, Lisa Duvick, Jillian Friedrich, Orion Rainwater, Praseuth Yang, Michael Benneyworth, Tessa Nichols-Meade, Wesley Heal, Rachel Ter Haar, Christine Henzler, Harry T. Orr

    Diterbitkan 2020-09-01
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  18. 18
    Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model

    Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model oleh Judit M. Pérez Ortiz, Nissa Mollema, Nicholas Toker, Carolyn J. Adamski, Brennon O'Callaghan, Lisa Duvick, Jillian Friedrich, Michael A. Walters, Jessica Strasser, Jon E. Hawkinson, Huda Y. Zoghbi, Christine Henzler, Harry T. Orr, Sarita Lagalwar

    Diterbitkan 2018-08-01
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  19. 19
    Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1

    Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1 oleh Won-Seok Lee, Ismael Al-Ramahi, Hyun-Hwan Jeong, Youjin Jang, Tao Lin, Carolyn J. Adamski, Laura A. Lavery, Smruti Rath, Ronald Richman, Vitaliy V. Bondar, Elizabeth Alcala, Jean-Pierre Revelli, Harry T. Orr, Zhandong Liu, Juan Botas, Huda Y. Zoghbi

    Diterbitkan 2022-05-01
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