Hasil Pencarian - Geoffrey L Greene

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  1. 1
    ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation

    ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation oleh Rosemary J. Huggins, Geoffrey L. Greene

    Diterbitkan 2023-11-01
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  2. 2
    Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination

    Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination oleh Ryan J. Bourgo, Hari Singhal, Geoffrey L. Greene

    Diterbitkan 2016-09-01
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  3. 3
    Reinvestigating the Synthesis and Characterization of Ethyl 3‑[5-(2-Ethoxycarbonyl-1-methylvinyloxy)-1-methyl‑1H‑indol-3-yl]-but-2-enoate

    Reinvestigating the Synthesis and Characterization of Ethyl 3‑[5-(2-Ethoxycarbonyl-1-methylvinyloxy)-1-methyl‑1H‑indol-3-yl]-but-2-enoate oleh Nan-Sheng Li, Joseph A. Piccirilli, Geoffrey L. Greene

    Diterbitkan 2023-08-01
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  4. 4
    Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics.

    Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics. oleh Joaquin Chapa, Ryan J Bourgo, Geoffrey L Greene, Swati Kulkarni, Gary An

    Diterbitkan 2013-01-01
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  5. 5
    Mapping ERβ genomic binding sites reveals unique genomic features and identifies EBF1 as an ERβ interactor.

    Mapping ERβ genomic binding sites reveals unique genomic features and identifies EBF1 as an ERβ interactor. oleh Thien P Le, Miao Sun, Xin Luo, W Lee Kraus, Geoffrey L Greene

    Diterbitkan 2013-01-01
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  6. 6
    Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells

    Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells oleh Svetlana E. Semina, Purab Pal, Nidhi S. Kansara, Rosemary J. Huggins, Elaine T. Alarid, Geoffrey L. Greene, Jonna Frasor

    Diterbitkan 2022-03-01
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  7. 7
    Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer

    Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer oleh Muriel Lainé, Marianne E Greene, Justyna D Kurleto, Grazyna Bozek, Tiffany Leng, Rosemary J Huggins, Barry S Komm, Geoffrey L Greene

    Diterbitkan 2024-06-01
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  8. 8
    Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer

    Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer oleh Muriel Lainé, Sean W. Fanning, Ya-Fang Chang, Bradley Green, Marianne E. Greene, Barry Komm, Justyna D. Kurleto, Linda Phung, Geoffrey L. Greene

    Diterbitkan 2021-05-01
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  9. 9
    Overcoming mutation-based resistance to antiandrogens with rational drug design

    Overcoming mutation-based resistance to antiandrogens with rational drug design oleh Minna D Balbas, Michael J Evans, David J Hosfield, John Wongvipat, Vivek K Arora, Philip A Watson, Yu Chen, Geoffrey L Greene, Yang Shen, Charles L Sawyers

    Diterbitkan 2013-04-01
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  10. 10
    Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells

    Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells oleh David J Hosfield, Sandra Weber, Nan-Sheng Li, Madline Sauvage, Carstyn F Joiner, Govinda R Hancock, Emily A Sullivan, Estelle Ndukwe, Ross Han, Sydney Cush, Muriel Lainé, Sylvie C Mader, Geoffrey L Greene, Sean W Fanning

    Diterbitkan 2022-05-01
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  11. 11
    Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

    Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation oleh Sean W Fanning, Christopher G Mayne, Venkatasubramanian Dharmarajan, Kathryn E Carlson, Teresa A Martin, Scott J Novick, Weiyi Toy, Bradley Green, Srinivas Panchamukhi, Benita S Katzenellenbogen, Emad Tajkhorshid, Patrick R Griffin, Yang Shen, Sarat Chandarlapaty, John A Katzenellenbogen, Geoffrey L Greene

    Diterbitkan 2016-02-01
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  12. 12
    The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

    The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells oleh Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Ross Han, Muriel Lainé, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W Nettles, Patrick R Griffin, Yang Shen, John A Katzenellenbogen, Myles Brown, Geoffrey L Greene

    Diterbitkan 2018-11-01
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  13. 13
    The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

    The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation oleh Anne Abot, Coralie Fontaine, Mélissa Buscato, Romain Solinhac, Gilles Flouriot, Aurélie Fabre, Anne Drougard, Shyamala Rajan, Muriel Laine, Alain Milon, Isabelle Muller, Daniel Henrion, Marine Adlanmerini, Marie‐Cécile Valéra, Anne Gompel, Céline Gerard, Christel Péqueux, Mélanie Mestdagt, Isabelle Raymond‐Letron, Claude Knauf, François Ferriere, Philippe Valet, Pierre Gourdy, Benita S Katzenellenbogen, John A Katzenellenbogen, Françoise Lenfant, Geoffrey L Greene, Jean‐Michel Foidart, Jean‐François Arnal

    Diterbitkan 2014-10-01
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  14. 14
    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

    The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer oleh Kimberly J. Cocce, Jeff S. Jasper, Taylor K. Desautels, Logan Everett, Suzanne Wardell, Thomas Westerling, Robert Baldi, Tricia M. Wright, Kendall Tavares, Alex Yllanes, Yeeun Bae, Jeremy T. Blitzer, Craig Logsdon, Daniel P. Rakiec, David A. Ruddy, Tiancong Jiang, Gloria Broadwater, Terry Hyslop, Allison Hall, Muriel Laine, Linda Phung, Geoffrey L. Greene, Lesley-Ann Martin, Sunil Pancholi, Mitch Dowsett, Simone Detre, Jeffrey R. Marks, Gregory E. Crawford, Myles Brown, John D. Norris, Ching-yi Chang, Donald P. McDonnell

    Diterbitkan 2019-10-01
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