Hasil Pencarian - Geoffrey I Shapiro

Perbaiki Hasil
  1. 1
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance oleh Liam Cornell, Seth A. Wander, Tanvi Visal, Nikhil Wagle, Geoffrey I. Shapiro

    Diterbitkan 2019-03-01
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  2. 2
    Sensitizing HR-proficient cancers to PARP inhibitors

    Sensitizing HR-proficient cancers to PARP inhibitors oleh Elgene Lim, Shawn F. Johnson, Matthias Geyer, Violeta Serra, Geoffrey I. Shapiro

    Diterbitkan 2017-11-01
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  3. 3
    STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer

    STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer oleh Constantia Pantelidou, Heta Jadhav, Aditi Kothari, Renyan Liu, Gerburg M. Wulf, Jennifer L. Guerriero, Geoffrey I. Shapiro

    Diterbitkan 2022-09-01
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  4. 4
    Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method

    Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method oleh Zahra Talebi, Dominique A. Garrison, Eric D. Eisenmann, Kalindi Parmar, Geoffrey I. Shapiro, Michelle A. Rudek, Alex Sparreboom, Yan Jin

    Diterbitkan 2023-11-01
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  5. 5
    Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma.

    Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma... oleh John C Morris, Antoinette R Tan, Thomas E Olencki, Geoffrey I Shapiro, Bruce J Dezube, Michael Reiss, Frank J Hsu, Jay A Berzofsky, Donald P Lawrence

    Diterbitkan 2014-01-01
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  6. 6
    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection

    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection oleh Mu-Yan Cai, Connor E. Dunn, Wenxu Chen, Bose S. Kochupurakkal, Huy Nguyen, Lisa A. Moreau, Geoffrey I. Shapiro, Kalindi Parmar, David Kozono, Alan D. D’Andrea

    Diterbitkan 2020-02-01
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  7. 7
    Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors

    Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors oleh Michael S. Gordon, Geoffrey I. Shapiro, John Sarantopoulos, Dejan Juric, Dejan Juric, Brian Lu, Angeliki Zarotiadou, Jamie N. Connarn, Yvan Le Bruchec, Calin Dan Dumitru, R. Donald Harvey

    Diterbitkan 2022-01-01
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  8. 8
    982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC)

    982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC) oleh Geoffrey I Shapiro, Anita Mehta, Jennifer L Guerriero, Adam Nelson, Patrice A Lee, Madisson Oliwa, Filipa Lynce, Nabihah Tayob, Madeline G Townsend, Kelly F Zheng, Nicholas A Saccomano

    Diterbitkan 2023-11-01
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  9. 9
    1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC

    1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC oleh Geoffrey I Shapiro, Jessica Thaxton, Anita Mehta, Jennifer L Guerriero, Adam Nelson, Carlos Wagner Wanderley, Filipa Lynce, Madeline G Townsend, Kelly F Zheng, Daniel E Michaud, Kiran Kurmi, Shakchhi Joshi, Marcia Haigis

    Diterbitkan 2023-11-01
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  10. 10
    Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET).

    Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET). oleh Roland T Ullrich, Thomas Zander, Bernd Neumaier, Mirjam Koker, Takeshi Shimamura, Yannic Waerzeggers, Christa L Borgman, Samir Tawadros, Hongfeng Li, Martin L Sos, Heiko Backes, Geoffrey I Shapiro, Jürgen Wolf, Andreas H Jacobs, Roman K Thomas, Alexandra Winkeler

    Diterbitkan 2008-01-01
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  11. 11
    RETRACTED ARTICLE: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

    RETRACTED ARTICLE: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer oleh Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero, Gerburg M. Wulf, Brian M. Wolpin, Ben Z. Stanger, Andrew J. Aguirre, James M. Cleary, Alan D. D’Andrea, Geoffrey I. Shapiro

    Diterbitkan 2023-03-01
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  12. 12
    Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

    Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer oleh Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero, Gerburg M. Wulf, Brian M. Wolpin, Ben Z. Stanger, Andrew J. Aguirre, James M. Cleary, Alan D. D’Andrea, Geoffrey I. Shapiro

    Diterbitkan 2023-12-01
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  13. 13
    First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers

    First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers oleh Xingfeng Bao, Andrea Varga, David S Hong, Aparna Parikh, Geoffrey I Shapiro, Özlem Ataman, Larisa Reyderman, Terri A Binder, Min Ren, Mingjie Liu, Satish Dayal, Amy Y Siu, Pallavi Sachdev, Lucy Xu, Vijay Bhagawati-Prasad, Ilian Tchakov, Chean Eng Ooi

    Diterbitkan 2020-06-01
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  14. 14
    Novel BRD2::NUTM1 Fusion in NUT Carcinoma With Exceptional Response to Chemotherapy: A Case Report

    Novel BRD2::NUTM1 Fusion in NUT Carcinoma With Exceptional Response to Chemotherapy: A Case Report oleh Sarah J. Wu, MD, PhD, Justin J. Kim, Yeying Huang, BS, R. Taylor Durall, BS, Simone Becker, RN, Stephanie Canty, CNP, MSN, Stefania Molinaro, BS, Evan Pisick, MD, Geoffrey I. Shapiro, MD, PhD, Christopher A. French, MD, Jia Luo, MD

    Diterbitkan 2024-01-01
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  15. 15
    Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer

    Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer oleh Melinda L. Telli, Sara M. Tolaney, Geoffrey I. Shapiro, Mark Middleton, Simon R. Lord, Hendrik Tobias Arkenau, Andrew Tutt, Vandana Abramson, Emma Dean, Tufia C. Haddad, Robert Wesolowski, Jordi Ferrer-Playan, Thomas Goddemeier, Thomas Grombacher, Jennifer Dong, Patricia Fleuranceau-Morel, Ivan Diaz-Padilla, Ruth Plummer

    Diterbitkan 2022-04-01
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  16. 16
    885 Characterization of the tumor microenvironment in advanced breast cancer patients treated with talazoparib followed by combination of talazoparib and avelumab

    885 Characterization of the tumor microenvironment in advanced breast cancer patients treated with talazoparib followed by combination of talazoparib and avelumab oleh Edward T Richardson, Geoffrey I Shapiro, Jennifer L Guerriero, Claudine Isaacs, Filipa Lynce, Madeline G Townsend, Kelly F Zheng, Paula R Pohlmann, Kenichi Shimada, Arielle Heeke, Xue Geng, Candace Mainor, Mei Wei, Julie M Collins, Lauren M Sloat, Jane Staunton, Stuart J Schnitt, Joan S Brugge, Hongkun Wang

    Diterbitkan 2023-11-01
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  17. 17
    Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13

    Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 oleh Mei Zeng, Nicholas P Kwiatkowski, Tinghu Zhang, Behnam Nabet, Mousheng Xu, Yanke Liang, Chunshan Quan, Jinhua Wang, Mingfeng Hao, Sangeetha Palakurthi, Shan Zhou, Qing Zeng, Paul T Kirschmeier, Khyati Meghani, Alan L Leggett, Jun Qi, Geoffrey I Shapiro, Joyce F Liu, Ursula A Matulonis, Charles Y Lin, Panagiotis A Konstantinopoulos, Nathanael S Gray

    Diterbitkan 2018-11-01
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  18. 18
    A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

    A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer oleh Panagiotis A. Konstantinopoulos, Alexandre André B. A. da Costa, Doga Gulhan, Elizabeth K. Lee, Su-Chun Cheng, Andrea E. Wahner Hendrickson, Bose Kochupurakkal, David L. Kolin, Elise C. Kohn, Joyce F. Liu, Elizabeth H. Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A. Matulonis, Anniina Färkkilä, Alan D. D’Andrea, Geoffrey I. Shapiro

    Diterbitkan 2021-09-01
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  19. 19
    Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

    Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer oleh Anniina Färkkilä, Doga C. Gulhan, Julia Casado, Connor A. Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu-An Chen, Denis Schapiro, Yinghui Zhou, Julie R. Graham, Bruce J. Dezube, Pamela Munster, Sandro Santagata, Elizabeth Garcia, Scott Rodig, Ana Lako, Dipanjan Chowdhury, Geoffrey I. Shapiro, Ursula A. Matulonis, Peter J. Park, Sampsa Hautaniemi, Peter K. Sorger, Elizabeth M. Swisher, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos

    Diterbitkan 2020-05-01
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  20. 20
    Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

    Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer oleh Anniina Färkkilä, Doga C. Gulhan, Julia Casado, Connor A. Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu-An Chen, Denis Schapiro, Yinghui Zhou, Julie R. Graham, Bruce J. Dezube, Pamela Munster, Sandro Santagata, Elizabeth Garcia, Scott Rodig, Ana Lako, Dipanjan Chowdhury, Geoffrey I. Shapiro, Ursula A. Matulonis, Peter J. Park, Sampsa Hautaniemi, Peter K. Sorger, Elizabeth M. Swisher, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos

    Diterbitkan 2020-03-01
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