Hasil Pencarian - Frank N. van Leeuwen

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  1. 1
    Therapeutic targeting of mutated p53 in acute lymphoblastic leukemia

    Therapeutic targeting of mutated p53 in acute lymphoblastic leukemia oleh Frank N. van Leeuwen

    Diterbitkan 2020-01-01
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  2. 2
    The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia

    The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia oleh René Marke, Frank N. van Leeuwen, Blanca Scheijen

    Diterbitkan 2018-04-01
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  3. 3
    Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

    Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. oleh Kristopher Clark, Jeroen Middelbeek, Nick A Morrice, Carl G Figdor, Edwin Lasonder, Frank N van Leeuwen

    Diterbitkan 2008-03-01
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  4. 4
    Creatine kinase-mediated ATP supply fuels actin-based events in phagocytosis.

    Creatine kinase-mediated ATP supply fuels actin-based events in phagocytosis. oleh Jan W P Kuiper, Helma Pluk, Frank Oerlemans, Frank N van Leeuwen, Frank de Lange, Jack Fransen, Bé Wieringa

    Diterbitkan 2008-03-01
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  5. 5
    Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton.

    Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton. oleh Esther Tijchon, Dorette van Ingen Schenau, Fred van Opzeeland, Felice Tirone, Peter M Hoogerbrugge, Frank N Van Leeuwen, Blanca Scheijen

    Diterbitkan 2015-01-01
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  6. 6
    Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development

    Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development oleh Esther Tijchon, Liesbeth van Emst, Laurensia Yuniati, Dorette van Ingen Schenau, Jørn Havinga, Jean-Pierre Rouault, Peter M. Hoogerbrugge, Frank N. van Leeuwen, Blanca Scheijen

    Diterbitkan 2016-07-01
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  7. 7
    The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution.

    The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution. oleh Esmé Waanders, Blanca Scheijen, Laurens T van der Meer, Simon V van Reijmersdal, Liesbeth van Emst, Yvet Kroeze, Edwin Sonneveld, Peter M Hoogerbrugge, Ad Geurts van Kessel, Frank N van Leeuwen, Roland P Kuiper

    Diterbitkan 2012-01-01
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  8. 8
    Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy

    Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy oleh Willem P.J. Cox, Nils Evander, Dorette S. van Ingen Schenau, Gawin R. Stoll, Nadia Anderson, Lieke de Groot, Kari J.T. Grünewald, Rico Hagelaar, Miriam Butler, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

    Diterbitkan 2023-12-01
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  9. 9
    Upfront Treatment Influences the Composition of Genetic Alterations in Relapsed Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

    Upfront Treatment Influences the Composition of Genetic Alterations in Relapsed Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia oleh Jiangyan Yu, Esmé Waanders, Simon V. van Reijmersdal, Željko Antić, Charlotte M. van Bosbeek, Edwin Sonneveld, Hester de Groot, Marta Fiocco, Ad Geurts van Kessel, Frank N. van Leeuwen, Rob Pieters, Peter M. Hoogerbrugge, Roland P. Kuiper

    Diterbitkan 2020-02-01
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  10. 10
    Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways

    Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways oleh Miriam Butler, Miriam Butler, Britt M.T. Vervoort, Dorette S. van Ingen Schenau, Lieneke Jongeneel, Jordy C.G. van der Zwet, René Marke, Jules P.P. Meijerink, Blanca Scheijen, Blanca Scheijen, Laurens T. van der Meer, Frank N. van Leeuwen

    Diterbitkan 2022-09-01
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  11. 11
    Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations

    Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations oleh Željko Antić, Jiangyan Yu, Simon V. van Reijmersdal, Anke van Dijk, Linde Dekker, Wouter H. Segerink, Edwin Sonneveld, Marta Fiocco, Rob Pieters, Peter M. Hoogerbrugge, Frank N. van Leeuwen, Ad Geurts van Kessel, Esme Waanders, Roland P. Kuiper

    Diterbitkan 2020-11-01
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  12. 12
    Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.

    Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant hetero... oleh Melanie M Hagleitner, Marieke J H Coenen, Ana Patino-Garcia, Eveline S J M de Bont, Anna Gonzalez-Neira, Hanneke I Vos, Frank N van Leeuwen, Hans Gelderblom, Peter M Hoogerbrugge, Henk-Jan Guchelaar, Maroeska W M Te Loo

    Diterbitkan 2014-01-01
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  13. 13
    The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

    The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia oleh Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N. van Leeuwen

    Diterbitkan 2023-05-01
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  14. 14
    The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia

    The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia oleh Annelienke M. van Hulst, Jordy C.G. van der Zwet, Jessica G.C.A.M. Buijs-Gladdines, Willem K. Smits, Marta Fiocco, Rob Pieters, Frank N. van Leeuwen, Marry M. van den Heuvel-Eibrink, Erica L.T. van den Akker, Jules P.P. Meijerink

    Diterbitkan 2024-01-01
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  15. 15
    Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

    Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade oleh Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller

    Diterbitkan 2022-01-01
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  16. 16
    <i>IKZF1</i> gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia

    <i>IKZF1</i> gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia oleh Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

    Diterbitkan 2024-06-01
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  17. 17
    Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

    Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients oleh Blanca Scheijen, Judith M. Boer, René Marke, Esther Tijchon, Dorette van Ingen Schenau, Esmé Waanders, Liesbeth van Emst, Laurens T. van der Meer, Rob Pieters, Gabriele Escherich, Martin A. Horstmann, Edwin Sonneveld, Nicola Venn, Rosemary Sutton, Luciano Dalla-Pozza, Roland P. Kuiper, Peter M. Hoogerbrugge, Monique L. den Boer, Frank N. van Leeuwen

    Diterbitkan 2017-03-01
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  18. 18
    Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

    Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. oleh Gordan Lauc, Jennifer E Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N van Leeuwen, L Renee Ruhaak, Jeanine J Houwing-Duistermaat, P Eline Slagboom, Marian Beekman, Anton J M de Craen, André M Deelder, Qiang Zeng, Wei Wang, Nicholas D Hastie, Ulf Gyllensten, James F Wilson, Manfred Wuhrer, Alan F Wright, Pauline M Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

    Diterbitkan 2013-01-01
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