UNLOCKING THE SECRETS OF PUBERTY ONSET: IS HYPOTHALAMIC LIPID-SENSING A KEY METABOLIC REGULATOR? by Elvira Rodríguez Vázquez, Álvaro Aranda Torrecillas, Cecilia Perdices López, Francisco Ruiz Pino, Ana Rodríguez Sánchez, Francisco Gaytán Luna, Juan Castellano Rodríguez, Manuel Tena Sempere

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Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway by Amparo Romero-Picó, Marta G. Novelle, Omar Al-Massadi, Daniel Beiroa, Marta Tojo, Violeta Heras, Francisco Ruiz-Pino, Ana Senra, Miguel López, Clemence Blouet, Manuel Tena-Sempere, Rubén Nogueiras, Carlos Diéguez

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Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson’s Disease and Amyotrophic Lateral Sclerosis by Sonia Burgaz, Concepción García, Claudia Gonzalo-Consuegra, Marta Gómez-Almería, Francisco Ruiz-Pino, Juan Diego Unciti, María Gómez-Cañas, Juan Alcalde, Paula Morales, Nadine Jagerovic, Carmen Rodríguez-Cueto, Eva de Lago, Eduardo Muñoz, Javier Fernández-Ruiz

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Cannabidiol markedly alleviates skin and liver fibrosis by Carmen del Río, Carmen del Río, Carmen del Río, Francisco Ruiz-Pino, María E. Prados, Bernd L. Fiebich, Manuel Tena-Sempere, Manuel Tena-Sempere, Manuel Tena-Sempere, Manuel Tena-Sempere, Eduardo Muñoz, Eduardo Muñoz, Eduardo Muñoz

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Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty by Maria Manfredi-Lozano, Juan Roa, Francisco Ruiz-Pino, Richard Piet, David Garcia-Galiano, Rafael Pineda, Aurora Zamora, Silvia Leon, Miguel A. Sanchez-Garrido, Antonio Romero-Ruiz, Carlos Dieguez, Maria Jesus Vazquez, Allan E. Herbison, Leonor Pinilla, Manuel Tena-Sempere

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Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress by Ismael González-García, Cristina Contreras, Ánxela Estévez-Salguero, Francisco Ruíz-Pino, Benoit Colsh, Iván Pensado, Laura Liñares-Pose, Eva Rial-Pensado, Pablo B. Martínez de Morentin, Johan Fernø, Carlos Diéguez, Rubén Nogueiras, Hervé Le Stunff, Christophe Magnan, Manuel Tena-Sempere, Miguel López

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Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice by Juan Roa, Miguel Ruiz-Cruz, Francisco Ruiz-Pino, Rocio Onieva, Maria J. Vazquez, Maria J. Sanchez-Tapia, Jose M. Ruiz-Rodriguez, Veronica Sobrino, Alexia Barroso, Violeta Heras, Inmaculada Velasco, Cecilia Perdices-Lopez, Claes Ohlsson, Maria Soledad Avendaño, Vincent Prevot, Matti Poutanen, Leonor Pinilla, Francisco Gaytan, Manuel Tena-Sempere

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Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3. by Violeta Heras, Susana Sangiao-Alvarellos, Maria Manfredi-Lozano, María J Sanchez-Tapia, Francisco Ruiz-Pino, Juan Roa, Maribel Lara-Chica, Rosario Morrugares-Carmona, Nathalie Jouy, Ana P Abreu, Vincent Prevot, Denise Belsham, Maria J Vazquez, Marco A Calzado, Leonor Pinilla, Francisco Gaytan, Ana C Latronico, Ursula B Kaiser, Juan M Castellano, Manuel Tena-Sempere

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Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy by Miguel A. Sánchez-Garrido, Víctor Serrano-López, Francisco Ruiz-Pino, María Jesús Vázquez, Andrea Rodríguez-Martín, Encarnación Torres, Inmaculada Velasco, Ana Belén Rodríguez, Eduardo Chicano-Gálvez, Marina Mora-Ortiz, Claes Ohlsson, Matti Poutanen, Leonor Pinilla, Francisco Gaytán, Jonathan D. Douros, Bin Yang, Timo D. Müller, Richard D. DiMarchi, Matthias H. Tschöp, Brian Finan, Manuel Tena-Sempere

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