P478: THE GERMLINE VARIANT GFI1-36N PROMOTES GENETIC INSTABILITY IN LEUKEMIC CELLS AND OPENS NEW THERAPEUTIC APPROACHES FOR ABOUT 15% OF ALL AML PATIENTS oleh J. Vorwerk, D. Frank, K. Sun, F. Neumannn, M. Heuser, D. Kunadt, W. E. Berdel, J.-H. Mikesch, C. Schliemann, G. Lenz, A. K. Jayavelu, C. Khandanpour