Search Results - Eric S. Lander

Eric Lander

Lander in 2023 Eric Steven Lander (born February 3, 1957) is an American mathematician and geneticist who is a professor of biology at the Massachusetts Institute of Technology (MIT), and a professor of systems biology at Harvard Medical School. Eric Lander is founding director emeritus of the Broad Institute of MIT and Harvard.

Lander served as the 11th director of the Office of Science and Technology Policy and Science Advisor to the President in Joe Biden's presidential Cabinet. In response to allegations that he had engaged in bullying and abusive conduct, Lander apologized and resigned from the Biden Administration effective February 18, 2022. Provided by Wikipedia
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  1. 1
    Gain-of-Function Claims for Type-2-Diabetes-Associated Coding Variants in SLC16A11 Are Not Supported by the Experimental Data

    Gain-of-Function Claims for Type-2-Diabetes-Associated Coding Variants in SLC16A11 Are Not Supported by the Experimental Data by Eitan Hoch, Jose C. Florez, Eric S. Lander, Suzanne B.R. Jacobs

    Published 2019-10-01
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  2. 2
    Identification and classification of conserved RNA secondary structures in the human genome.

    Identification and classification of conserved RNA secondary structures in the human genome. by Jakob Skou Pedersen, Gill Bejerano, Adam Siepel, Kate Rosenbloom, Kerstin Lindblad-Toh, Eric S Lander, Jim Kent, Webb Miller, David Haussler

    Published 2006-04-01
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  3. 3
    Advancing early onset colorectal cancer research: research advocacy, health disparities, and scientific imperatives

    Advancing early onset colorectal cancer research: research advocacy, health disparities, and scientific imperatives by Andrea J. Dwyer, Aniruddha Rathod, Carli King, F. E. R. Vuik, Phuong Gallagher, Anjee Davis, Eric M. Lander, Jose Perea

    Published 2024-07-01
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  4. 4
    The case for selection at CCR5-Delta32.

    The case for selection at CCR5-Delta32. by Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander

    Published 2005-11-01
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  5. 5
    CK1epsilon is required for breast cancers dependent on beta-catenin activity.

    CK1epsilon is required for breast cancers dependent on beta-catenin activity. by So Young Kim, Ian F Dunn, Ron Firestein, Piyush Gupta, Leslie Wardwell, Kara Repich, Anna C Schinzel, Ben Wittner, Serena J Silver, David E Root, Jesse S Boehm, Sridhar Ramaswamy, Eric S Lander, William C Hahn

    Published 2010-02-01
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  6. 6
    Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.

    Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease. by Manish D Paranjpe, Mark Chaffin, Sohail Zahid, Scott Ritchie, Jerome I Rotter, Stephen S Rich, Robert Gerszten, Xiuqing Guo, Susan Heckbert, Russ Tracy, John Danesh, Eric S Lander, Michael Inouye, Sekar Kathiresan, Adam S Butterworth, Amit V Khera

    Published 2022-09-01
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  7. 7
    Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

    Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. by Manching Ku, Richard P Koche, Esther Rheinbay, Eric M Mendenhall, Mitsuhiro Endoh, Tarjei S Mikkelsen, Aviva Presser, Chad Nusbaum, Xiaohui Xie, Andrew S Chi, Mazhar Adli, Simon Kasif, Leon M Ptaszek, Chad A Cowan, Eric S Lander, Haruhiko Koseki, Bradley E Bernstein

    Published 2008-10-01
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  8. 8
    Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.

    Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction. by Aenne S Thormaehlen, Christian Schuberth, Hong-Hee Won, Peter Blattmann, Brigitte Joggerst-Thomalla, Susanne Theiss, Rosanna Asselta, Stefano Duga, Pier Angelica Merlini, Diego Ardissino, Eric S Lander, Stacey Gabriel, Daniel J Rader, Gina M Peloso, Rainer Pepperkok, Sekar Kathiresan, Heiko Runz

    Published 2015-02-01
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  9. 9
    Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

    Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features by John P. Ray, Carl G. de Boer, Charles P. Fulco, Caleb A. Lareau, Masahiro Kanai, Jacob C. Ulirsch, Ryan Tewhey, Leif S. Ludwig, Steven K. Reilly, Drew T. Bergman, Jesse M. Engreitz, Robbyn Issner, Hilary K. Finucane, Eric S. Lander, Aviv Regev, Nir Hacohen

    Published 2020-03-01
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  10. 10
    Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

    Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions by Akl C. Fahed, Minxian Wang, Julian R. Homburger, Aniruddh P. Patel, Alexander G. Bick, Cynthia L. Neben, Carmen Lai, Deanna Brockman, Anthony Philippakis, Patrick T. Ellinor, Christopher A. Cassa, Matthew Lebo, Kenney Ng, Eric S. Lander, Alicia Y. Zhou, Sekar Kathiresan, Amit V. Khera

    Published 2020-08-01
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  11. 11
    Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

    Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites by Schraga Schwartz, Maxwell R. Mumbach, Marko Jovanovic, Tim Wang, Karolina Maciag, G. Guy Bushkin, Philipp Mertins, Dmitry Ter-Ovanesyan, Naomi Habib, Davide Cacchiarelli, Neville E. Sanjana, Elizaveta Freinkman, Michael E. Pacold, Rahul Satija, Tarjei S. Mikkelsen, Nir Hacohen, Feng Zhang, Steven A. Carr, Eric S. Lander, Aviv Regev

    Published 2014-07-01
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  12. 12
    A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

    A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients by Andrew Brantley Hall, Moran Yassour, Jenny Sauk, Ashley Garner, Xiaofang Jiang, Timothy Arthur, Georgia K. Lagoudas, Tommi Vatanen, Nadine Fornelos, Robin Wilson, Madeline Bertha, Melissa Cohen, John Garber, Hamed Khalili, Dirk Gevers, Ashwin N. Ananthakrishnan, Subra Kugathasan, Eric S. Lander, Paul Blainey, Hera Vlamakis, Ramnik J. Xavier, Curtis Huttenhower

    Published 2017-11-01
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  13. 13
    ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.

    ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. by Ellen Markljung, Lin Jiang, Jacob D Jaffe, Tarjei S Mikkelsen, Ola Wallerman, Martin Larhammar, Xiaolan Zhang, Li Wang, Veronica Saenz-Vash, Andreas Gnirke, Anders M Lindroth, Romain Barrés, Jie Yan, Sara Strömberg, Sachinandan De, Fredrik Pontén, Eric S Lander, Steven A Carr, Juleen R Zierath, Klas Kullander, Claes Wadelius, Kerstin Lindblad-Toh, Göran Andersson, Göran Hjälm, Leif Andersson

    Published 2009-12-01
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  14. 14
    Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

    Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. by Noriko Tonomura, Ingegerd Elvers, Rachael Thomas, Kate Megquier, Jason Turner-Maier, Cedric Howald, Aaron L Sarver, Ross Swofford, Aric M Frantz, Daisuke Ito, Evan Mauceli, Maja Arendt, Hyun Ji Noh, Michele Koltookian, Tara Biagi, Sarah Fryc, Christina Williams, Anne C Avery, Jong-Hyuk Kim, Lisa Barber, Kristine Burgess, Eric S Lander, Elinor K Karlsson, Chieko Azuma, Jaime F Modiano, Matthew Breen, Kerstin Lindblad-Toh

    Published 2015-02-01
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  15. 15
    An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.

    An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts. by Marc P Hoeppner, Andrew Lundquist, Mono Pirun, Jennifer R S Meadows, Neda Zamani, Jeremy Johnson, Görel Sundström, April Cook, Michael G FitzGerald, Ross Swofford, Evan Mauceli, Behrooz Torabi Moghadam, Anna Greka, Jessica Alföldi, Amr Abouelleil, Lynne Aftuck, Daniel Bessette, Aaron Berlin, Adam Brown, Gary Gearin, Annie Lui, J Pendexter Macdonald, Margaret Priest, Terrance Shea, Jason Turner-Maier, Andrew Zimmer, Eric S Lander, Federica di Palma, Kerstin Lindblad-Toh, Manfred G Grabherr

    Published 2014-01-01
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  16. 16
    Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

    Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma by Marios Giannakis, Xinmeng Jasmine Mu, Sachet A. Shukla, Zhi Rong Qian, Ofir Cohen, Reiko Nishihara, Samira Bahl, Yin Cao, Ali Amin-Mansour, Mai Yamauchi, Yasutaka Sukawa, Chip Stewart, Mara Rosenberg, Kosuke Mima, Kentaro Inamura, Katsuhiko Nosho, Jonathan A. Nowak, Michael S. Lawrence, Edward L. Giovannucci, Andrew T. Chan, Kimmie Ng, Jeffrey A. Meyerhardt, Eliezer M. Van Allen, Gad Getz, Stacey B. Gabriel, Eric S. Lander, Catherine J. Wu, Charles S. Fuchs, Shuji Ogino, Levi A. Garraway

    Published 2016-04-01
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  17. 17
    Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

    Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma by Marios Giannakis, Xinmeng Jasmine Mu, Sachet A. Shukla, Zhi Rong Qian, Ofir Cohen, Reiko Nishihara, Samira Bahl, Yin Cao, Ali Amin-Mansour, Mai Yamauchi, Yasutaka Sukawa, Chip Stewart, Mara Rosenberg, Kosuke Mima, Kentaro Inamura, Katsuhiko Nosho, Jonathan A. Nowak, Michael S. Lawrence, Edward L. Giovannucci, Andrew T. Chan, Kimmie Ng, Jeffrey A. Meyerhardt, Eliezer M. Van Allen, Gad Getz, Stacey B. Gabriel, Eric S. Lander, Catherine J. Wu, Charles S. Fuchs, Shuji Ogino, Levi A. Garraway

    Published 2016-10-01
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  18. 18
    Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

    Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. by Daria Van Tyne, Daniel J Park, Stephen F Schaffner, Daniel E Neafsey, Elaine Angelino, Joseph F Cortese, Kayla G Barnes, David M Rosen, Amanda K Lukens, Rachel F Daniels, Danny A Milner, Charles A Johnson, Ilya Shlyakhter, Sharon R Grossman, Justin S Becker, Daniel Yamins, Elinor K Karlsson, Daouda Ndiaye, Ousmane Sarr, Souleymane Mboup, Christian Happi, Nicholas A Furlotte, Eleazar Eskin, Hyun Min Kang, Daniel L Hartl, Bruce W Birren, Roger C Wiegand, Eric S Lander, Dyann F Wirth, Sarah K Volkman, Pardis C Sabeti

    Published 2011-04-01
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  19. 19
    Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

    Deep-coverage whole genome sequences and blood lipids among 16,324 individuals by Pradeep Natarajan, Gina M. Peloso, Seyedeh Maryam Zekavat, May Montasser, Andrea Ganna, Mark Chaffin, Amit V. Khera, Wei Zhou, Jonathan M. Bloom, Jesse M. Engreitz, Jason Ernst, Jeffrey R. O’Connell, Sanni E. Ruotsalainen, Maris Alver, Ani Manichaikul, W. Craig Johnson, James A. Perry, Timothy Poterba, Cotton Seed, Ida L. Surakka, Tonu Esko, Samuli Ripatti, Veikko Salomaa, Adolfo Correa, Ramachandran S. Vasan, Manolis Kellis, Benjamin M. Neale, Eric S. Lander, Goncalo Abecasis, Braxton Mitchell, Stephen S. Rich, James G. Wilson, L. Adrienne Cupples, Jerome I. Rotter, Cristen J. Willer, Sekar Kathiresan, NHLBI TOPMed Lipids Working Group

    Published 2018-08-01
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  20. 20
    The Human Cell Atlas

    The Human Cell Atlas by Aviv Regev, Sarah A Teichmann, Eric S Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Göttgens, Nir Hacohen, Muzlifah Haniffa, Martin Hemberg, Seung Kim, Paul Klenerman, Arnold Kriegstein, Ed Lein, Sten Linnarsson, Emma Lundberg, Joakim Lundeberg, Partha Majumder, John C Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn, Mihai Netea, Garry Nolan, Dana Pe'er, Anthony Phillipakis, Chris P Ponting, Stephen Quake, Wolf Reik, Orit Rozenblatt-Rosen, Joshua Sanes, Rahul Satija, Ton N Schumacher, Alex Shalek, Ehud Shapiro, Padmanee Sharma, Jay W Shin, Oliver Stegle, Michael Stratton, Michael J T Stubbington, Fabian J Theis, Matthias Uhlen, Alexander van Oudenaarden, Allon Wagner, Fiona Watt, Jonathan Weissman, Barbara Wold, Ramnik Xavier, Nir Yosef, Human Cell Atlas Meeting Participants

    Published 2017-12-01
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