Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms oleh Matthew Mealka, Nicole A. Sierra, Diego Avellaneda Matteo, Elene Albekioni, Rachel Khoury, Timothy Mai, Brittany M. Conley, Nalani J. Coleman, Kaitlyn A. Sabo, Elizabeth A. Komives, Andrey A. Bobkov, Andrew L. Cooksy, Steve Silletti, Jamie M. Schiffer, Tom Huxford, Christal D. Sohl