Hasil Pencarian - Dennis J Selkoe

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  1. 1
    Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol

    Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol oleh Ming Jin, Dennis J. Selkoe

    Diterbitkan 2015-10-01
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  2. 2
    The amyloid hypothesis of Alzheimer's disease at 25 years

    The amyloid hypothesis of Alzheimer's disease at 25 years oleh Dennis J Selkoe, John Hardy

    Diterbitkan 2016-03-01
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  3. 3
    LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

    LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model oleh Babak Nazer, Soyon Hong, Dennis J. Selkoe

    Diterbitkan 2008-04-01
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  4. 4
    Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid β-protein metabolism in mouse models of Alzheimer disease

    Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid β-protein metabolism in mouse models of Alzheimer disease oleh Matthew L. Hemming, Dennis J. Selkoe, Wesley Farris

    Diterbitkan 2007-04-01
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  5. 5
    Small non-fibrillar assemblies of amyloid β-protein bearing the Arctic mutation induce rapid neuritic degeneration

    Small non-fibrillar assemblies of amyloid β-protein bearing the Arctic mutation induce rapid neuritic degeneration oleh Brian M. Whalen, Dennis J. Selkoe, Dean M. Hartley

    Diterbitkan 2005-11-01
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  6. 6
    Protofibrils of amyloid β-protein inhibit specific K+ currents in neocortical cultures

    Protofibrils of amyloid β-protein inhibit specific K+ currents in neocortical cultures oleh Chian P Ye, Dennis J Selkoe, Dean M Hartley

    Diterbitkan 2003-08-01
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  7. 7
    Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β

    Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β oleh Huixin Xu, Molly M Rajsombath, Pia Weikop, Dennis J Selkoe

    Diterbitkan 2023-01-01
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  8. 8
    N-alpha-acetylation of α-synuclein increases its helical folding propensity, GM1 binding specificity and resistance to aggregation.

    N-alpha-acetylation of α-synuclein increases its helical folding propensity, GM1 binding specificity and resistance to aggregation. oleh Tim Bartels, Nora C Kim, Eric S Luth, Dennis J Selkoe

    Diterbitkan 2014-01-01
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  9. 9
    Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β

    Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β oleh Huixin Xu, Molly M Rajsombath, Pia Weikop, Dennis J Selkoe

    Diterbitkan 2018-09-01
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  10. 10
    Receptor-Mediated Transport of Human Amyloid β-Protein 1–40 and 1–42 at the Blood–Brain Barrier

    Receptor-Mediated Transport of Human Amyloid β-Protein 1–40 and 1–42 at the Blood–Brain Barrier oleh Joseph F. Poduslo, Geoffry L. Curran, Bharati Sanyal, Dennis J. Selkoe

    Diterbitkan 1999-06-01
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  11. 11
    Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain

    Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain oleh Diane T. Stephenson, Cynthia A. Lemere, Dennis J. Selkoe, James A. Clemens

    Diterbitkan 1996-02-01
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  12. 12
    Identification of beta-secretase (BACE1) substrates using quantitative proteomics.

    Identification of beta-secretase (BACE1) substrates using quantitative proteomics. oleh Matthew L Hemming, Joshua E Elias, Steven P Gygi, Dennis J Selkoe

    Diterbitkan 2009-12-01
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  13. 13
    Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.

    Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements. oleh Matthew L Hemming, Joshua E Elias, Steven P Gygi, Dennis J Selkoe

    Diterbitkan 2008-10-01
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  14. 14
    Soluble Aβ Oligomers Impair Dipolar Heterodendritic Plasticity by Activation of mGluR in the Hippocampal CA1 Region

    Soluble Aβ Oligomers Impair Dipolar Heterodendritic Plasticity by Activation of mGluR in the Hippocampal CA1 Region oleh Jianhua Zhao, Anna Li, Molly Rajsombath, Yifan Dang, Dennis J. Selkoe, Shaomin Li

    Diterbitkan 2018-08-01
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  15. 15
    Aβ oligomers from human brain impair mossy fiber LTP in CA3 of hippocampus, but activating cAMP-PKA and cGMP-PKG prevents this

    Aβ oligomers from human brain impair mossy fiber LTP in CA3 of hippocampus, but activating cAMP-PKA and cGMP-PKG prevents this oleh Shan-Xue Jin, Lei Liu, Shaomin Li, Angela L. Meunier, Dennis J. Selkoe

    Diterbitkan 2022-10-01
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  16. 16
    Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease

    Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease oleh Shaomin Li, Ming Jin, Lei Liu, Yifan Dang, Beth L. Ostaszewski, Dennis J. Selkoe

    Diterbitkan 2018-11-01
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  17. 17
    The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

    The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase oleh David M Bolduc, Daniel R Montagna, Matthew C Seghers, Michael S Wolfe, Dennis J Selkoe

    Diterbitkan 2016-08-01
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  18. 18
    Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

    Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease. oleh Matthew L Hemming, Michaela Patterson, Casper Reske-Nielsen, Ling Lin, Ole Isacson, Dennis J Selkoe

    Diterbitkan 2007-08-01
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  19. 19
    Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing

    Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing oleh Anja Leona Biere, Beth Ostaszewski, Hongwei Zhao, Susan Gillespie, Steven G. Younkin, Dennis J. Selkoe

    Diterbitkan 1995-06-01
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  20. 20
    Aggregation and catabolism of disease-associated intra-Aβ mutations: reduced proteolysis of AβA21G by neprilysin

    Aggregation and catabolism of disease-associated intra-Aβ mutations: reduced proteolysis of AβA21G by neprilysin oleh Vicki Betts, Malcolm A. Leissring, Georgia Dolios, Rong Wang, Dennis J. Selkoe, Dominic M. Walsh

    Diterbitkan 2008-09-01
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