Hasil Pencarian - David Ortega-Alarcon

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  1. 1
    Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners

    Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners oleh José L. Neira, David Ortega-Alarcón, Bruno Rizzuti, Martina Palomino-Schätzlein, Adrián Velázquez-Campoy, Alberto Falcó

    Diterbitkan 2021-10-01
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  2. 2
    Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2

    Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2 oleh David Ortega-Alarcon, Rafael Claveria-Gimeno, Sonia Vega, Olga C. Jorge-Torres, Manel Esteller, Olga Abian, Adrian Velazquez-Campoy

    Diterbitkan 2021-08-01
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  3. 3
    Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2

    Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2 oleh David Ortega-Alarcon, Rafael Claveria-Gimeno, Sonia Vega, Olga C. Jorge-Torres, Manel Esteller, Olga Abian, Adrian Velazquez-Campoy

    Diterbitkan 2020-11-01
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  4. 4
    Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds

    Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds oleh Bruno Rizzuti, Laura Ceballos-Laita, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Fedora Grande, Filomena Conforti, Olga Abian, Adrian Velazquez-Campoy

    Diterbitkan 2021-09-01
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  5. 5
    Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs

    Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs oleh Bruno Rizzuti, Fedora Grande, Filomena Conforti, Ana Jimenez-Alesanco, Laura Ceballos-Laita, David Ortega-Alarcon, Sonia Vega, Hugh T. Reyburn, Olga Abian, Adrian Velazquez-Campoy

    Diterbitkan 2021-04-01
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  6. 6
    Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 M<sup>pro</sup> Main Protease Inhibitors

    Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 M<sup>pro</sup> Main Protease Inhibitors oleh Maria Nuria Peralta-Moreno, Vanessa Anton-Muñoz, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Timothy M. Thomson, José Manuel Granadino-Roldán, Claudia Machicado, Jaime Rubio-Martinez

    Diterbitkan 2023-04-01
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  7. 7
    Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 M<sup>pro</sup> Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation

    Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 M<sup>pro</sup> Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation oleh Maria Nuria Peralta-Moreno, Yago Mena, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Timothy M. Thomson, Marta Pinto, José M. Granadino-Roldán, Maria Santos Tomas, Juan J. Perez, Jaime Rubio-Martinez

    Diterbitkan 2024-06-01
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  8. 8
    <span style="font-variant: small-caps">l</span>-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells

    <span style="font-variant: small-caps">l</span>-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells oleh Luca Sancineto, Carmine Ostacolo, David Ortega-Alarcon, Ana Jimenez-Alesanco, Laura Ceballos-Laita, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Silvia Moretti, Agnieszka Dabrowska, Pawel Botwina, Aleksandra Synowiec, Anna Kula-Pacurar, Krzysztof Pyrc, Nunzio Iraci, Claudio Santi

    Diterbitkan 2021-10-01
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  9. 9
    Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M<sup>pro</sup> and Its Antiviral Activity in Cells against SARS-CoV-2

    Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M<sup>pro</sup> and Its Antiviral Activity in Cells against SARS-CoV-2 oleh Francesca Mangiavacchi, Pawel Botwina, Elena Menichetti, Luana Bagnoli, Ornelio Rosati, Francesca Marini, Sérgio F. Fonseca, Laura Abenante, Diego Alves, Agnieszka Dabrowska, Anna Kula-Pacurar, David Ortega-Alarcon, Ana Jimenez-Alesanco, Laura Ceballos-Laita, Sonia Vega, Bruno Rizzuti, Olga Abian, Eder J. Lenardão, Adrian Velazquez-Campoy, Krzysztof Pyrc, Luca Sancineto, Claudio Santi

    Diterbitkan 2021-06-01
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