Hasil Pencarian - David M. Sabatini

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  1. 1
    CellProfiler™: free, versatile software for automated biological image analysis

    CellProfiler™: free, versatile software for automated biological image analysis oleh Michael R. Lamprecht, David M. Sabatini, Anne E. Carpenter

    Diterbitkan 2007-01-01
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  2. 2
    Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.

    Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. oleh William T Festuccia, Philippe Pouliot, Inan Bakan, David M Sabatini, Mathieu Laplante

    Diterbitkan 2014-01-01
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  3. 3
    Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1

    Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1 oleh Lawrence D. Schweitzer, William C. Comb, Liron Bar-Peled, David M. Sabatini

    Diterbitkan 2015-09-01
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  4. 4
    An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

    An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway oleh Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

    Diterbitkan 2024-03-01
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  5. 5
    Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2

    Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2 oleh Lan eYe, Behzad eVaramini, Dudley W. Lamming, David M. Sabatini, Joseph A. Baur

    Diterbitkan 2012-09-01
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  6. 6
    A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells

    A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells oleh G. Jordan Ray, Elizabeth A. Boydston, Emily Shortt, Gregory A. Wyant, Sebastian Lourido, Walter W. Chen, David M. Sabatini

    Diterbitkan 2020-05-01
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  7. 7
    Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

    Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity oleh Alexandre Caron, Sébastien M. Labbé, Damien Lanfray, Pierre-Gilles Blanchard, Romain Villot, Christian Roy, David M. Sabatini, Denis Richard, Mathieu Laplante

    Diterbitkan 2016-02-01
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  8. 8
    A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

    A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility oleh Christopher J. Yuskaitis, Brandon M. Jones, Rachel L. Wolfson, Chloe E. Super, Sameer C. Dhamne, Alexander Rotenberg, David M. Sabatini, Mustafa Sahin, Annapurna Poduri

    Diterbitkan 2018-03-01
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  9. 9
    The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

    The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1 oleh Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco, Robert A. Saxton, Sonia M. Scaria, Liron Bar-Peled, Eric Spooner, Marta Isasa, Steven P. Gygi, David M. Sabatini

    Diterbitkan 2014-10-01
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  10. 10
    Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

    Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates oleh Zhou Yu, Lauren E Surface, Chong Yon Park, Max A Horlbeck, Gregory A Wyant, Monther Abu-Remaileh, Timothy R Peterson, David M Sabatini, Jonathan S Weissman, Erin K O'Shea

    Diterbitkan 2018-05-01
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  11. 11
    Loss of hepatic DEPTOR alters the metabolic transition to fasting

    Loss of hepatic DEPTOR alters the metabolic transition to fasting oleh Alexandre Caron, Mathilde Mouchiroud, Nicolas Gautier, Sébastien M. Labbé, Romain Villot, Laurie Turcotte, Blandine Secco, Guillaume Lamoureux, Michael Shum, Yves Gélinas, André Marette, Denis Richard, David M. Sabatini, Mathieu Laplante

    Diterbitkan 2017-05-01
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  12. 12
    Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

    Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity oleh Yong Yu, Shihong M Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu, Bentian Jing, Qian Zhao, David M Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C Wang

    Diterbitkan 2024-01-01
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  13. 13
    Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells

    Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells oleh Walter W. Chen, Kıvanç Birsoy, Maria M. Mihaylova, Harriet Snitkin, Iwona Stasinski, Burcu Yucel, Erol C. Bayraktar, Jan E. Carette, Clary B. Clish, Thijn R. Brummelkamp, David D. Sabatini, David M. Sabatini

    Diterbitkan 2014-04-01
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  14. 14
    C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly

    C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly oleh Nadia Rasheed, Tatiani B. Lima, Gustavo F. Mercaldi, Andrey F.Z. Nascimento, Ana L.S. Silva, Germanna L. Righetto, Liron Bar‐Peled, Kuang Shen, David M. Sabatini, Fabio C. Gozzo, Ricardo Aparicio, Juliana H.C. Smetana

    Diterbitkan 2019-09-01
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  15. 15
    Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction

    Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction oleh Jacob M Winter, Heidi L Fresenius, Corey N Cunningham, Peng Wei, Heather R Keys, Jordan Berg, Alex Bott, Tarun Yadav, Jeremy Ryan, Deepika Sirohi, Sheryl R Tripp, Paige Barta, Neeraj Agarwal, Anthony Letai, David M Sabatini, Matthew L Wohlever, Jared Rutter

    Diterbitkan 2022-11-01
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  16. 16
    Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling

    Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling oleh Celia de la Calle Arregui, Ana Belén Plata-Gómez, Nerea Deleyto-Seldas, Fernando García, Ana Ortega-Molina, Julio Abril-Garrido, Elena Rodriguez, Ivan Nemazanyy, Laura Tribouillard, Alba de Martino, Eduardo Caleiras, Ramón Campos-Olivas, Francisca Mulero, Mathieu Laplante, Javier Muñoz, Mario Pende, Guadalupe Sabio, David M. Sabatini, Alejo Efeyan

    Diterbitkan 2021-06-01
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  17. 17
    ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State

    ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State oleh Yakov Chudnovsky, Dohoon Kim, Siyuan Zheng, Warren A. Whyte, Mukesh Bansal, Mark-Anthony Bray, Shuba Gopal, Matthew A. Theisen, Steve Bilodeau, Prathapan Thiru, Julien Muffat, Omer H. Yilmaz, Maya Mitalipova, Kevin Woolard, Jeongwu Lee, Riko Nishimura, Nobuo Sakata, Howard A. Fine, Anne E. Carpenter, Serena J. Silver, Roel G.W. Verhaak, Andrea Califano, Richard A. Young, Keith L. Ligon, Ingo K. Mellinghoff, David E. Root, David M. Sabatini, William C. Hahn, Milan G. Chheda

    Diterbitkan 2014-01-01
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