Hasil Pencarian - David J. Beech

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  1. 1
    Correspondence: Challenging a proposed role for TRPC5 in aortic baroreceptor pressure-sensing

    Correspondence: Challenging a proposed role for TRPC5 in aortic baroreceptor pressure-sensing oleh Pratish Thakore, Susan D. Brain, David J. Beech

    Diterbitkan 2018-03-01
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  2. 2
    Pico145 inhibits TRPC4-mediated mICAT and postprandial small intestinal motility

    Pico145 inhibits TRPC4-mediated mICAT and postprandial small intestinal motility oleh Dariia O. Dryn, Mariia I. Melnyk, Robin S. Bon, David J. Beech, Alexander V. Zholos

    Diterbitkan 2023-12-01
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  3. 3
    Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site

    Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site oleh David J. Wright, Katie J. Simmons, Rachel M. Johnson, David J. Beech, Stephen P. Muench, Robin S. Bon

    Diterbitkan 2020-11-01
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  4. 4
    Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease

    Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease oleh Aisling Minard, Claudia C. Bauer, David J. Wright, Hussein N. Rubaiy, Katsuhiko Muraki, David J. Beech, Robin S. Bon

    Diterbitkan 2018-06-01
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  5. 5
    ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling

    ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling oleh Heba Shawer, Katherine Norman, Katherine Norman, Chew W. Cheng, Richard Foster, Richard Foster, David J. Beech, Marc A. Bailey

    Diterbitkan 2021-04-01
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  6. 6
    Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

    Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells oleh Vincenza Caolo, Marjolaine Debant, Naima Endesh, T Simon Futers, Laeticia Lichtenstein, Fiona Bartoli, Gregory Parsonage, Elizabeth AV Jones, David J Beech

    Diterbitkan 2020-06-01
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  7. 7
    Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

    Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels oleh Jian Shi, Adam J. Hyman, Dario De Vecchis, Jiehan Chong, Laeticia Lichtenstein, T. Simon Futers, Myriam Rouahi, Anne Negre Salvayre, Nathalie Auge, Antreas C. Kalli, David J. Beech

    Diterbitkan 2020-10-01
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  8. 8
    Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca2+ entry in HEK293 cells

    Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca2+ entry in HEK293 cells oleh Katherine Norman, Karen E. Hemmings, Heba Shawer, Hollie L. Appleby, Alan J. Burnett, Nurasyikin Hamzah, Rajendra Gosain, Emily M. Woodhouse, David J. Beech, Richard Foster, Marc A. Bailey

    Diterbitkan 2024-01-01
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  9. 9
    Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice

    Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice oleh Fiona Bartoli, Elizabeth L. Evans, Nicola M. Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E. Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T. Simon Futers, Neil A. Turner, David J. Beech

    Diterbitkan 2022-04-01
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  10. 10
    Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory

    Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory oleh Sophie Lepannetier, Roberta Gualdani, Sabrina Tempesta, Olivier Schakman, François Seghers, Anna Kreis, Xavier Yerna, Amina Slimi, Marie de Clippele, Nicolas Tajeddine, Thomas Voets, Robin S. Bon, David J. Beech, Fadel Tissir, Philippe Gailly

    Diterbitkan 2018-09-01
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  11. 11
    Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity

    Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity oleh Fiona Bartoli, Marjolaine Debant, Eulashini Chuntharpursat-Bon, Elizabeth L. Evans, Katie E. Musialowski, Gregory Parsonage, Lara C. Morley, T. Simon Futers, Piruthivi Sukumar, T. Scott Bowen, Mark T. Kearney, Laeticia Lichtenstein, Lee D. Roberts, David J. Beech

    Diterbitkan 2022-03-01
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  12. 12
    Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy

    Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy oleh Talia Caspi, Sam Straw, Chew Cheng, Jack O Garnham, Jason L. Scragg, Jessica Smith, Aaron O. Koshy, Eylem Levelt, Piruthivi Sukumar, John Gierula, David J. Beech, Mark T. Kearney, Richard M. Cubbon, Stephen B. Wheatcroft, Klaus K. Witte, Lee D. Roberts, T. Scott Bowen

    Diterbitkan 2020-09-01
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  13. 13
    PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing

    PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing oleh Eulashini Chuntharpursat-Bon, Oleksandr V. Povstyan, Melanie J. Ludlow, David J. Carrier, Marjolaine Debant, Jian Shi, Hannah J. Gaunt, Claudia C. Bauer, Alistair Curd, T. Simon Futers, Paul D. Baxter, Michelle Peckham, Stephen P. Muench, Antony Adamson, Neil Humphreys, Sarka Tumova, Robin S. Bon, Richard Cubbon, Laeticia Lichtenstein, David J. Beech

    Diterbitkan 2023-04-01
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  14. 14
    Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

    Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development oleh Laura J. Brylka, Assil-Ramin Alimy, Miriam E. A. Tschaffon-Müller, Shan Jiang, Tobias Malte Ballhause, Anke Baranowsky, Simon von Kroge, Julian Delsmann, Eva Pawlus, Kian Eghbalian, Klaus Püschel, Astrid Schoppa, Melanie Haffner-Luntzer, David J. Beech, Frank Timo Beil, Michael Amling, Johannes Keller, Anita Ignatius, Timur A. Yorgan, Tim Rolvien, Thorsten Schinke

    Diterbitkan 2024-02-01
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  15. 15
    Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

    Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance oleh Baptiste Rode, Jian Shi, Naima Endesh, Mark J. Drinkhill, Peter J. Webster, Sabine J. Lotteau, Marc A. Bailey, Nadira Y. Yuldasheva, Melanie J. Ludlow, Richard M. Cubbon, Jing Li, T. Simon Futers, Lara Morley, Hannah J. Gaunt, Katarzyna Marszalek, Hema Viswambharan, Kevin Cuthbertson, Paul D. Baxter, Richard Foster, Piruthivi Sukumar, Andrew Weightman, Sarah C. Calaghan, Stephen B. Wheatcroft, Mark T. Kearney, David J. Beech

    Diterbitkan 2017-08-01
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