Hasil Pencarian - David J Rawlings

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  1. 1
    Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

    Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses oleh Harriet A. Purvis, Fiona Clarke, Anna B. Montgomery, Chloe Colas, Jack A. Bibby, Georgina H. Cornish, Xuezhi Dai, Xuezhi Dai, Xuezhi Dai, Diana Dudziak, David J. Rawlings, David J. Rawlings, David J. Rawlings, Rose Zamoyska, Pierre Guermonprez, Pierre Guermonprez, Andrew P. Cope

    Diterbitkan 2020-03-01
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  2. 2
    The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner

    The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner oleh Amanda J. Stock, Pierina Gonzalez Paredes, Luciana Previato de Almeida, Stanley D. Kosanke, Srinivaas Chetlur, Hannah Budde, Paul Wakenight, Theresa A. Zwingman, Aaron B.I. Rosen, Eric J. Allenspach, Eric J. Allenspach, Kathleen J. Millen, Kathleen J. Millen, Jane H. Buckner, David J. Rawlings, David J. Rawlings, David J. Rawlings, Jacquelyn A. Gorman

    Diterbitkan 2024-02-01
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  3. 3
    An optimized measles virus glycoprotein-pseudotyped lentiviral vector production system to promote efficient transduction of human primary B cells

    An optimized measles virus glycoprotein-pseudotyped lentiviral vector production system to promote efficient transduction of human primary B cells oleh Eirini Vamva, Stosh Ozog, Els Verhoeyen, Richard G. James, David J. Rawlings, Bruce E. Torbett

    Diterbitkan 2022-03-01
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  4. 4
    PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses

    PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses oleh Warren Anderson, Fariba Barahmand-pour-Whitman, Peter S Linsley, Karen Cerosaletti, Jane H Buckner, David J Rawlings

    Diterbitkan 2023-03-01
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  5. 5
    Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI.

    Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. oleh Martine Aubert, Byoung Y Ryu, Lindsey Banks, David J Rawlings, Andrew M Scharenberg, Keith R Jerome

    Diterbitkan 2011-02-01
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  6. 6
    The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets

    The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets oleh Jacquelyn A. Gorman, Christian Hundhausen, Mackenzie Kinsman, Tanvi Arkatkar, Eric J. Allenspach, Eric J. Allenspach, Courtnee Clough, Samuel E. West, Kerri Thomas, Kerri Thomas, Ahmet Eken, Socheath Khim, Malika Hale, Malika Hale, Mohamed Oukka, Mohamed Oukka, Mohamed Oukka, Shaun W. Jackson, Shaun W. Jackson, Karen Cerosaletti, Jane H. Buckner, David J. Rawlings, David J. Rawlings, David J. Rawlings

    Diterbitkan 2019-01-01
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  7. 7
    Efficient Enrichment of Gene-Modified Primary T Cells via CCR5-Targeted Integration of Mutant Dihydrofolate Reductase

    Efficient Enrichment of Gene-Modified Primary T Cells via CCR5-Targeted Integration of Mutant Dihydrofolate Reductase oleh Biswajit Paul, Guillermo S. Romano Ibarra, Nicholas Hubbard, Teresa Einhaus, Alexander Astrakhan, David J. Rawlings, Hans-Peter Kiem, Christopher W. Peterson

    Diterbitkan 2018-06-01
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  8. 8
    1703 Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing endoplasmic reticulum stress

    1703 Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing endoplasmic reticulum stress oleh David J Rawlings, Christopher D Thouvenel, Baidong Hou, Fahd Al Qureshah, Sara Sagadiev, Shuozhi Liu, Zhaolin Hua, Mridu Acharya, Richard G James

    Diterbitkan 2021-11-01
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  9. 9
    Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus

    Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus oleh Swati Singh, Leah J. Homad, Nicholas R. Akins, Claire M. Stoffers, Stefan Lackhar, Harman Malhi, Yu-Hsin Wan, David J. Rawlings, Andrew T. McGuire

    Diterbitkan 2020-06-01
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  10. 10
    In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods

    In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods oleh Sowmya Pattabhi, Samantha N. Lotti, Mason P. Berger, Swati Singh, Christopher T. Lux, Kyle Jacoby, Calvin Lee, Olivier Negre, Andrew M. Scharenberg, David J. Rawlings

    Diterbitkan 2019-09-01
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  11. 11
    In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease

    In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease oleh Martine Aubert, Nicole M Boyle, Daniel Stone, Laurence Stensland, Meei-Li Huang, Amalia S Magaret, Roman Galetto, David J Rawlings, Andrew M Scharenberg, Keith R Jerome

    Diterbitkan 2014-01-01
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  12. 12
    1709 A threshold of B cell costimulatory signals is required for spontaneous germinal center formation in autoimmunity

    1709 A threshold of B cell costimulatory signals is required for spontaneous germinal center formation in autoimmunity oleh David J Rawlings, Quan-Zhen Li, Christopher D Thouvenel, Tanvi Arkatkar, Shaun W Jackson, Kristy Chiang, Andrea D Largent, Samuel W Du, Natali Shumlak, Jonathan Woods

    Diterbitkan 2021-11-01
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  13. 13
    Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector

    Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector oleh Swati Singh, Iram Khan, Socheath Khim, Brenda Seymour, Karen Sommer, Matthew Wielgosz, Zachary Norgaard, Hans-Peter Kiem, Jennifer Adair, Denny Liggitt, Arthur Nienhuis, David J. Rawlings

    Diterbitkan 2017-03-01
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  14. 14
    Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome

    Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome oleh Swati Singh, Cole M. Pugliano, Yuchi Honaker, Aidan Laird, M. Quinn DeGottardi, Ezra Lopez, Stefan Lachkar, Claire Stoffers, Karen Sommer, Iram F. Khan, David J. Rawlings

    Diterbitkan 2024-03-01
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  15. 15
    pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences

    pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences oleh Alexandra E Grier, Stephen Burleigh, Jaya Sahni, Courtnee A Clough, Victoire Cardot, Dongwook C Choe, Michelle C Krutein, David J Rawlings, Michael C Jensen, Andrew M Scharenberg, Kyle Jacoby

    Diterbitkan 2016-01-01
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  16. 16
    203 Insights into lupus biology from inborn errors of immunity: immunopathogenesis of STAT1 gain-of- function autoimmunity

    203 Insights into lupus biology from inborn errors of immunity: immunopathogenesis of STAT1 gain-of- function autoimmunity oleh David J Rawlings, Troy Torgerson, Quan-Zhen Li, Shaun W Jackson, Largent Andrea, Kathi Lambert, Chiang Kristy, Shumlak Natali, Kelly Hudkins, Denny Liggitt, Mohammed Oukka, Jane Buckner, Eric Allenspach

    Diterbitkan 2022-12-01
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  17. 17
    Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells

    Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells oleh Malika Hale, Baeckseung Lee, Yuchi Honaker, Wai-Hang Leung, Alexandra E. Grier, Holly M. Jacobs, Karen Sommer, Jaya Sahni, Shaun W. Jackson, Andrew M. Scharenberg, Alexander Astrakhan, David J. Rawlings

    Diterbitkan 2017-03-01
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  18. 18
    Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance

    Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance oleh Guillermo S Romano Ibarra, Biswajit Paul, Blythe D Sather, Patrick M Younan, Karen Sommer, John P Kowalski, Malika Hale, Barry Stoddard, Jordan Jarjour, Alexander Astrakhan, Hans-Peter Kiem, David J Rawlings

    Diterbitkan 2016-01-01
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  19. 19
    TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction

    TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction oleh Christopher T. Lux, Sowmya Pattabhi, Mason Berger, Cynthia Nourigat, David A. Flowers, Olivier Negre, Olivier Humbert, Julia G. Yang, Calvin Lee, Kyle Jacoby, Irwin Bernstein, Hans-Peter Kiem, Andrew Scharenberg, David J. Rawlings

    Diterbitkan 2019-03-01
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  20. 20
    Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells.

    Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells. oleh Fiona Clarke, Christine K Jordan, Enrique Gutiérrez-Martinez, Jack A Bibby, Cristina Sanchez-Blanco, Georgina H Cornish, Xuezhi Dai, David J Rawlings, Rose Zamoyska, Pierre Guermonprez, Andrew P Cope, Harriet A Purvis

    Diterbitkan 2017-01-01
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