Hasil Pencarian - David B Ascher

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  1. 1
    Known allosteric proteins have central roles in genetic disease.

    Known allosteric proteins have central roles in genetic disease. oleh György Abrusán, David B Ascher, Michael Inouye

    Diterbitkan 2022-02-01
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  2. 2
    Identifying the Molecular Drivers of Pathogenic Aldehyde Dehydrogenase Missense Mutations in Cancer and Non-Cancer Diseases

    Identifying the Molecular Drivers of Pathogenic Aldehyde Dehydrogenase Missense Mutations in Cancer and Non-Cancer Diseases oleh Dana Jessen-Howard, Qisheng Pan, David B. Ascher

    Diterbitkan 2023-06-01
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  3. 3
    CSM-Toxin: A Web-Server for Predicting Protein Toxicity

    CSM-Toxin: A Web-Server for Predicting Protein Toxicity oleh Vladimir Morozov, Carlos H. M. Rodrigues, David B. Ascher

    Diterbitkan 2023-01-01
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  4. 4
    Mutations in Glycosyltransferases and Glycosidases: Implications for Associated Diseases

    Mutations in Glycosyltransferases and Glycosidases: Implications for Associated Diseases oleh Xiaotong Gu, Aaron S. Kovacs, Yoochan Myung, David B. Ascher

    Diterbitkan 2024-04-01
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  5. 5
    Insights from Spatial Measures of Intolerance to Identifying Pathogenic Variants in Developmental and Epileptic Encephalopathies

    Insights from Spatial Measures of Intolerance to Identifying Pathogenic Variants in Developmental and Epileptic Encephalopathies oleh Michael Silk, Alex de Sá, Moshe Olshansky, David B. Ascher

    Diterbitkan 2023-03-01
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  6. 6
    A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility

    A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility oleh Jennifer C. Boer, Qisheng Pan, Qisheng Pan, Jessica K. Holien, Thanh-Binh Nguyen, Thanh-Binh Nguyen, David B. Ascher, David B. Ascher, Magdalena Plebanski

    Diterbitkan 2022-12-01
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  7. 7
    Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2

    Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2 oleh Raghad Aljarf, Mengyuan Shen, Douglas E. V. Pires, David B. Ascher

    Diterbitkan 2022-06-01
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  8. 8
    Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery

    Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery oleh Shannon Jewell, Thanh Binh Nguyen, David B. Ascher, Avril A.B. Robertson

    Diterbitkan 2024-12-01
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  9. 9
    Estimating tuberculosis drug resistance amplification rates in high-burden settings

    Estimating tuberculosis drug resistance amplification rates in high-burden settings oleh Malancha Karmakar, Romain Ragonnet, David B. Ascher, James M. Trauer, Justin T. Denholm

    Diterbitkan 2022-01-01
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  10. 10
    Combining structure and genomics to understand antimicrobial resistance

    Combining structure and genomics to understand antimicrobial resistance oleh Tanushree Tunstall, Stephanie Portelli, Jody Phelan, Taane G. Clark, David B. Ascher, Nicholas Furnham

    Diterbitkan 2020-01-01
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  11. 11
    HGDiscovery: An online tool providing functional and phenotypic information on novel variants of homogentisate 1,2- dioxigenase

    HGDiscovery: An online tool providing functional and phenotypic information on novel variants of homogentisate 1,2- dioxigenase oleh Malancha Karmakar, Vittoria Cicaloni, Carlos H.M. Rodrigues, Ottavia Spiga, Annalisa Santucci, David B. Ascher

    Diterbitkan 2022-01-01
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  12. 12
    piscesCSM: prediction of anticancer synergistic drug combinations

    piscesCSM: prediction of anticancer synergistic drug combinations oleh Raghad AlJarf, Carlos H. M. Rodrigues, Yoochan Myung, Douglas E. V. Pires, David B. Ascher

    Diterbitkan 2024-07-01
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  13. 13
    PRIMITI: A computational approach for accurate prediction of miRNA-target mRNA interaction

    PRIMITI: A computational approach for accurate prediction of miRNA-target mRNA interaction oleh Korawich Uthayopas, Alex G.C. de Sá, Azadeh Alavi, Douglas E.V. Pires, David B. Ascher

    Diterbitkan 2024-12-01
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  14. 14
    Distinguishing between PTEN clinical phenotypes through mutation analysis

    Distinguishing between PTEN clinical phenotypes through mutation analysis oleh Stephanie Portelli, Lucy Barr, Alex G.C. de Sá, Douglas E.V. Pires, David B. Ascher

    Diterbitkan 2021-01-01
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  15. 15
    TSMDA: Target and symptom-based computational model for miRNA-disease-association prediction

    TSMDA: Target and symptom-based computational model for miRNA-disease-association prediction oleh Korawich Uthayopas, Alex G.C. de Sá, Azadeh Alavi, Douglas E.V. Pires, David B. Ascher

    Diterbitkan 2021-12-01
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  16. 16
    Empirical ways to identify novel Bedaquiline resistance mutations in AtpE.

    Empirical ways to identify novel Bedaquiline resistance mutations in AtpE. oleh Malancha Karmakar, Carlos H M Rodrigues, Kathryn E Holt, Sarah J Dunstan, Justin Denholm, David B Ascher

    Diterbitkan 2019-01-01
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  17. 17
    Use of the energy waveform electrocardiogram to detect subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus

    Use of the energy waveform electrocardiogram to detect subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus oleh Cheng Hwee Soh, Alex G. C. de Sá, Elizabeth Potter, Amera Halabi, David B. Ascher, Thomas H. Marwick

    Diterbitkan 2024-03-01
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  18. 18
    Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

    Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania brazili... oleh Juliano A. Souza Silva, Luiza G. Tunes, Roney S. Coimbra, David B. Ascher, Douglas E.V. Pires, Rubens L. Monte-Neto

    Diterbitkan 2021-01-01
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  19. 19
    Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase

    Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase oleh Yunzhuo Zhou, Stephanie Portelli, Megan Pat, Carlos H.M. Rodrigues, Thanh-Binh Nguyen, Douglas E.V. Pires, David B. Ascher

    Diterbitkan 2021-01-01
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  20. 20
    Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae

    Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae oleh Sundeep Chaitanya Vedithi, Carlos H.M. Rodrigues, Stephanie Portelli, Marcin J. Skwark, Madhusmita Das, David B. Ascher, Tom L. Blundell, Sony Malhotra

    Diterbitkan 2020-01-01
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