Hasil Pencarian - David A Sinclair

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  1. 1
    Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice

    Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice oleh Golam Mezbah Uddin, Neil A Youngson, David A Sinclair, David A Sinclair, Margaret J Morris

    Diterbitkan 2016-08-01
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  2. 2
    Can artificial intelligence identify effective COVID‐19 therapies?

    Can artificial intelligence identify effective COVID‐19 therapies? oleh Michael B Schultz, Daniel Vera, David A Sinclair

    Diterbitkan 2020-08-01
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  3. 3
    MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.

    MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. oleh Oliver Medvedik, Dudley W Lamming, Keyman D Kim, David A Sinclair

    Diterbitkan 2007-10-01
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  4. 4
    Correction: nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

    Correction: nicotinamide impairs entry into and exit from meiosis I in mouse oocytes. oleh Angelique Riepsamen, Lindsay Wu, Laurin Lau, Dave Listijono, William Ledger, David A Sinclair, Hayden Homer

    Diterbitkan 2015-01-01
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  5. 5
    Novel feature selection methods for construction of accurate epigenetic clocks.

    Novel feature selection methods for construction of accurate epigenetic clocks. oleh Adam Li, Amber Mueller, Brad English, Anthony Arena, Daniel Vera, Alice E Kane, David A Sinclair

    Diterbitkan 2022-08-01
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  6. 6
    Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

    Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers oleh Golam M. Uddin, Neil A. Youngson, Sabiha S. Chowdhury, Christopher Hagan, David A. Sinclair, Margaret J. Morris

    Diterbitkan 2020-03-01
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  7. 7
    The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice

    The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice oleh Qing-Shuo Zhang, Matthew Deater, Kathryn Schubert, Laura Marquez-Loza, Carl Pelz, David A. Sinclair, Markus Grompe

    Diterbitkan 2015-07-01
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  8. 8
    The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function

    The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function oleh João S. Teodoro, João A. Amorim, Ivo F. Machado, Ana C. Castela, Clemens Steegborn, David A. Sinclair, Anabela P. Rolo, Carlos M. Palmeira

    Diterbitkan 2020-07-01
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  9. 9
    Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung

    Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung oleh Pierre Montay-Gruel, Yafeng Zhu, Benoit Petit, Ron Leavitt, Mike Warn, Erich Giedzinski, Jonathan Ollivier, David A. Sinclair, Marie-Catherine Vozenin, Charles L. Limoli

    Diterbitkan 2021-03-01
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  10. 10
    Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila

    Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila oleh Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon

    Diterbitkan 2022-11-01
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  11. 11
    Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells

    Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells oleh Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, Brigitte Izac, Rebeca Dieguez-Gonzalez, Gaetan Barbet, Michael Donovan, Carlo Brugnara, Julie M. Blander, David A. Sinclair, Saghi Ghaffari

    Diterbitkan 2014-07-01
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  12. 12
    Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty

    Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty oleh Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair

    Diterbitkan 2020-10-01
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  13. 13
    Age and life expectancy clocks based on machine learning analysis of mouse frailty

    Age and life expectancy clocks based on machine learning analysis of mouse frailty oleh Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair

    Diterbitkan 2020-09-01
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  14. 14
    NMN Supplementation Rescues Fertility and Bone Strength in Chemotherapy-Treated Mice

    NMN Supplementation Rescues Fertility and Bone Strength in Chemotherapy-Treated Mice oleh Maria B. MARINOVA, Wing-Hong Jonathan HO, Michael J. BERTOLDO, Vedran LOVRIC, Kaisa SELESNIEMI, William R. WALSH, David A. SINCLAIR, Kirsty WALTERS, Robert B. GILCHRIST, Lindsay E. WU

    Diterbitkan 2022-09-01
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  15. 15
    JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks

    JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks oleh Michael Van Meter, Matthew Simon, Gregory Tombline, Alfred May, Timothy D. Morello, Basil P. Hubbard, Katie Bredbenner, Rosa Park, David A. Sinclair, Vilhelm A. Bohr, Vera Gorbunova, Andrei Seluanov

    Diterbitkan 2016-09-01
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  16. 16
    Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.

    Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy. oleh Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen

    Diterbitkan 2014-01-01
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  17. 17
    The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

    The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. oleh Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair

    Diterbitkan 2008-04-01
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  18. 18
    Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice

    Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice oleh Shanlin Ke, Sarah J. Mitchell, Michael R. MacArthur, Alice E. Kane, David A. Sinclair, Emily M. Venable, Katia S. Chadaideh, Rachel N. Carmody, Francine Grodstein, James R. Mitchell, Yang-Yu Liu

    Diterbitkan 2021-09-01
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  19. 19
    Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

    Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... oleh Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari

    Diterbitkan 2019-06-01
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  20. 20
    Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography

    Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography oleh Juan A. Martínez‐Greene, Karina Hernández‐Ortega, Ricardo Quiroz‐Baez, Osbaldo Resendis‐Antonio, Israel Pichardo‐Casas, David A. Sinclair, Bogdan Budnik, Alfredo Hidalgo‐Miranda, Eileen Uribe‐Querol, María del Pilar Ramos‐Godínez, Eduardo Martínez‐Martínez

    Diterbitkan 2021-04-01
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