Hasil Pencarian - David A Fidock

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  1. 1
    Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites.

    Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites. oleh Andrew H Lee, David A Fidock

    Diterbitkan 2016-01-01
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  2. 2
    Hemozoin Promotes Lung Inflammation via Host Epithelial Activation

    Hemozoin Promotes Lung Inflammation via Host Epithelial Activation oleh Shivang S. Shah, David A. Fidock, Alice S. Prince

    Diterbitkan 2021-02-01
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  3. 3
    Malaria's missing number: calculating the human component of R0 by a within-host mechanistic model of Plasmodium falciparum infection and transmission.

    Malaria's missing number: calculating the human component of R0 by a within-host mechanistic model of Plasmodium falciparum infection and transmission. oleh Geoffrey L Johnston, David L Smith, David A Fidock

    Diterbitkan 2013-04-01
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  4. 4
    Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin

    Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin oleh Lucien Platon, Didier Leroy, David A. Fidock, Didier Ménard

    Diterbitkan 2024-04-01
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  5. 5
    Modeling within-host effects of drugs on Plasmodium falciparum transmission and prospects for malaria elimination.

    Modeling within-host effects of drugs on Plasmodium falciparum transmission and prospects for malaria elimination. oleh Geoffrey L Johnston, Peter W Gething, Simon I Hay, David L Smith, David A Fidock

    Diterbitkan 2014-01-01
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  6. 6
    Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

    Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound oleh Emilee E. Colón-Lorenzo, Daisy D. Colón-López, Joel Vega-Rodríguez, Alice Dupin, David A. Fidock, David A. Fidock, Abel Baerga-Ortiz, José G. Ortiz, Jürgen Bosch, Jürgen Bosch, Jürgen Bosch, Adelfa E. Serrano

    Diterbitkan 2020-03-01
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  7. 7
    <italic toggle="yes">Plasmodium falciparum</italic> K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness <italic toggle="yes">In Vitro</italic>

    <italic toggle="yes">Plasmodium falciparum</italic> K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness <italic toggle="yes">In Vitro</italic> oleh Judith Straimer, Nina F. Gnädig, Barbara H. Stokes, Michelle Ehrenberger, Audrey A. Crane, David A. Fidock

    Diterbitkan 2017-05-01
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  8. 8
    <named-content content-type="genus-species">Plasmodium berghei</named-content> K13 Mutations Mediate <italic toggle="yes">In Vivo</italic> Artemisinin Resistance That Is Reversed by Proteasome Inhibition

    <named-content content-type="genus-species">Plasmodium berghei</named-content> K13 Mutations Mediate <italic toggle="yes">In Vivo</italic> Artemisinin Resistance That Is Reversed b... oleh Nelson V. Simwela, Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters

    Diterbitkan 2020-12-01
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  9. 9
    Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.

    Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum. oleh Stephanie G Valderramos, Juan-Carlos Valderramos, Lise Musset, Lisa A Purcell, Odile Mercereau-Puijalon, Eric Legrand, David A Fidock

    Diterbitkan 2010-05-01
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  10. 10
    Global Spread of Mutant PfCRT and Its Pleiotropic Impact on <named-content content-type="genus-species">Plasmodium falciparum</named-content> Multidrug Resistance and Fitness

    Global Spread of Mutant PfCRT and Its Pleiotropic Impact on <named-content content-type="genus-species">Plasmodium falciparum</named-content> Multidrug Resistance and Fitness oleh Satish K. Dhingra, Stanislaw J. Gabryszewski, Jennifer L. Small-Saunders, Tomas Yeo, Philipp P. Henrich, Sachel Mok, David A. Fidock

    Diterbitkan 2019-04-01
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  11. 11
    Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target.

    Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target. oleh Paul Gratraud, Enlli Huws, Brie Falkard, Sophie Adjalley, David A Fidock, Laurence Berry, William R Jacobs, Mark S Baird, Henri Vial, Laurent Kremer

    Diterbitkan 2009-09-01
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  12. 12
    Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.

    Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages. oleh John Okombo, Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath, Lindsey M Orchard, Edward Owens, Imhoi Koo, Istvan Albert, Manuel Llinás, David A Fidock

    Diterbitkan 2022-10-01
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  13. 13
    Expansion of a Specific <named-content content-type="genus-species">Plasmodium falciparum</named-content> PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

    Expansion of a Specific <named-content content-type="genus-species">Plasmodium falciparum</named-content> PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport oleh Carla Calçada, Miguel Silva, Vitória Baptista, Vandana Thathy, Rita Silva-Pedrosa, Diana Granja, Pedro Eduardo Ferreira, José Pedro Gil, David A. Fidock, Maria Isabel Veiga

    Diterbitkan 2020-12-01
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  14. 14
    Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies

    Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies oleh M. Isabel Veiga, Satish K. Dhingra, Philipp P. Henrich, Judith Straimer, Nina Gnädig, Anne-Catrin Uhlemann, Rowena E. Martin, Adele M. Lehane, David A. Fidock

    Diterbitkan 2016-05-01
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  15. 15
    Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

    Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine oleh Leila S. Ross, Satish K. Dhingra, Sachel Mok, Tomas Yeo, Kathryn J. Wicht, Krittikorn Kümpornsin, Shannon Takala-Harrison, Benoit Witkowski, Rick M. Fairhurst, Frederic Ariey, Didier Menard, David A. Fidock

    Diterbitkan 2018-08-01
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  16. 16
    Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.

    Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents. oleh Barbara H Stokes, Euna Yoo, James M Murithi, Madeline R Luth, Pavel Afanasyev, Paula C A da Fonseca, Elizabeth A Winzeler, Caroline L Ng, Matthew Bogyo, David A Fidock

    Diterbitkan 2019-06-01
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  17. 17
    Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

    Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility oleh Clare R. Harding, Saima M. Sidik, Boryana Petrova, Nina F. Gnädig, John Okombo, Alice L. Herneisen, Kurt E. Ward, Benedikt M. Markus, Elizabeth A. Boydston, David A. Fidock, Sebastian Lourido

    Diterbitkan 2020-09-01
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  18. 18
    Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine

    Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine oleh Eva Stadler, Mohamed Maiga, Lukas Friedrich, Vandana Thathy, Claudia Demarta-Gatsi, Antoine Dara, Fanta Sogore, Josefine Striepen, Claude Oeuvray, Abdoulaye A. Djimdé, Marcus C. S. Lee, Laurent Dembélé, David A. Fidock, David S. Khoury, Thomas Spangenberg

    Diterbitkan 2023-09-01
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  19. 19
    Propensity of selecting mutant parasites for the antimalarial drug cabamiquine

    Propensity of selecting mutant parasites for the antimalarial drug cabamiquine oleh Eva Stadler, Mohamed Maiga, Lukas Friedrich, Vandana Thathy, Claudia Demarta-Gatsi, Antoine Dara, Fanta Sogore, Josefine Striepen, Claude Oeuvray, Abdoulaye A. Djimdé, Marcus C. S. Lee, Laurent Dembélé, David A. Fidock, David S. Khoury, Thomas Spangenberg

    Diterbitkan 2023-08-01
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  20. 20
    Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival

    Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival oleh Sachel Mok, Barbara H. Stokes, Nina F. Gnädig, Leila S. Ross, Tomas Yeo, Chanaki Amaratunga, Erik Allman, Lev Solyakov, Andrew R. Bottrill, Jaishree Tripathi, Rick M. Fairhurst, Manuel Llinás, Zbynek Bozdech, Andrew B. Tobin, David A. Fidock

    Diterbitkan 2021-01-01
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