Hasil Pencarian - David J. Kwiatkowski

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  1. 1
    mTOR Inhibitors in Cancer: What Can We Learn from Exceptional Responses?

    mTOR Inhibitors in Cancer: What Can We Learn from Exceptional Responses? oleh David J. Kwiatkowski, Nikhil Wagle, MD

    Diterbitkan 2015-01-01
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  2. 2
    Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment

    Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment oleh Yan Tang, David J. Kwiatkowski, Elizabeth P. Henske

    Diterbitkan 2022-08-01
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  3. 3
    Robust method for distinguishing heterozygous from homozygous transgenic alleles by multiplex ligation-dependent probe assay

    Robust method for distinguishing heterozygous from homozygous transgenic alleles by multiplex ligation-dependent probe assay oleh Piotr Kozlowski, Mei Lin, Lynsey Meikle, David J. Kwiatkowski

    Diterbitkan 2007-05-01
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  4. 4
    Design and Generation of MLPA Probe Sets for Combined Copy Number and Small-Mutation Analysis of Human Genes: EGFR as an Example

    Design and Generation of MLPA Probe Sets for Combined Copy Number and Small-Mutation Analysis of Human Genes: EGFR as an Example oleh Malgorzata Marcinkowska, Kwok-Kin Wong, David J. Kwiatkowski, Piotr Kozlowski

    Diterbitkan 2010-01-01
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  5. 5
    Therapeutic trial of metformin and bortezomib in a mouse model of tuberous sclerosis complex (TSC).

    Therapeutic trial of metformin and bortezomib in a mouse model of tuberous sclerosis complex (TSC). oleh Neil Auricchio, Izabela Malinowska, Reuben Shaw, Brendan D Manning, David J Kwiatkowski

    Diterbitkan 2012-01-01
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  6. 6
    Analysis of a Mouse Skin Model of Tuberous Sclerosis Complex.

    Analysis of a Mouse Skin Model of Tuberous Sclerosis Complex. oleh Yanan Guo, John R Dreier, Juxiang Cao, Heng Du, Scott R Granter, David J Kwiatkowski

    Diterbitkan 2016-01-01
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  7. 7
    Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.

    Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer. oleh Evelyn M Mrozek, Vineeta Bajaj, Yanan Guo, Izabela A Malinowska, Jianming Zhang, David J Kwiatkowski

    Diterbitkan 2021-01-01
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  8. 8
    Angiomyolipoma have common mutations in TSC2 but no other common genetic events.

    Angiomyolipoma have common mutations in TSC2 but no other common genetic events. oleh Wei Qin, Vineeta Bajaj, Izabela Malinowska, Xin Lu, Laura MacConaill, Chin-Lee Wu, David J Kwiatkowski

    Diterbitkan 2011-01-01
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  9. 9
    Diagnosis of Mosaic Tuberous Sclerosis Complex Using Next-Generation Sequencing of Subtle or Unusual Cutaneous Findings

    Diagnosis of Mosaic Tuberous Sclerosis Complex Using Next-Generation Sequencing of Subtle or Unusual Cutaneous Findings oleh Alison M. Treichel, Barbara Boeszoermenyi, Chyi-Chia Richard Lee, Joel Moss, David J. Kwiatkowski, Thomas N. Darling

    Diterbitkan 2023-03-01
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  10. 10
    mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

    mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion oleh Heng-Jia Liu, Heng Du, Damir Khabibullin, Mahsa Zarei, Kevin Wei, Gordon J. Freeman, David J. Kwiatkowski, Elizabeth P. Henske

    Diterbitkan 2023-03-01
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  11. 11
    mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals.

    mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals. oleh Po-Shun Lee, Anna S K Wilhelmson, Anton P Hubner, Samuel B Reynolds, Dana A Gallacchi, Terry T Chiou, David J Kwiatkowski

    Diterbitkan 2010-12-01
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  12. 12
    Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value.

    Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value. oleh Yvonne Chekaluk, Chin-Lee Wu, Jonathan Rosenberg, Markus Riester, Qishan Dai, Sharron Lin, Yanan Guo, W Scott McDougal, David J Kwiatkowski

    Diterbitkan 2013-01-01
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  13. 13
    Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex

    Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex oleh Katarzyna Klonowska, Joannes M. Grevelink, Krinio Giannikou, Barbara A. Ogorek, Zachary T. Herbert, Aaron R. Thorner, Thomas N. Darling, Joel Moss, David J. Kwiatkowski

    Diterbitkan 2022-05-01
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  14. 14
    Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1

    Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1 oleh Heng Du, Yu Chi Yang, Heng-Jia Liu, Min Yuan, John M. Asara, Kwok-Kin Wong, Elizabeth P. Henske, Mallika Singh, David J. Kwiatkowski

    Diterbitkan 2023-11-01
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  15. 15
    Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model

    Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model oleh Shilpa Prabhakar, Xuan Zhang, June Goto, Sangyeul Han, Charles Lai, Roderick Bronson, Miguel Sena-Esteves, Vijaya Ramesh, Anat Stemmer-Rachamimov, David J. Kwiatkowski, Xandra O. Breakefield

    Diterbitkan 2015-10-01
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  16. 16
    Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.

    Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis. oleh Chenggang Li, Erik Zhang, Yang Sun, Po-Shun Lee, Yongzhong Zhan, Yanan Guo, Juan C Osorio, Ivan O Rosas, Kai-Feng Xu, David J Kwiatkowski, Jane J Yu

    Diterbitkan 2014-01-01
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  17. 17
    Correction: Stochastic Model of Lesions in Mouse Brain.

    Correction: Stochastic Model of Lesions in Mouse Brain. oleh Shilpa Prabhakar, June Goto, Xuan Zhang, Miguel Sena-Esteves, Roderick Bronson, Jillian Brockmann, Davide Gianni, Gregory R. Wojtkiewicz, John W. Chen, Anat Stemmer-Rachamimov, David J. Kwiatkowski, Xandra O. Breakefield

    Diterbitkan 2013-01-01
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  18. 18
    Stochastic model of Tsc1 lesions in mouse brain.

    Stochastic model of Tsc1 lesions in mouse brain. oleh Shilpa Prabhakar, June Goto, Xuan Zhang, Miguel Sena-Esteves, Roderick Bronson, Jillian Brockmann, Davide Gianni, Gregory R Wojtkiewicz, John W Chen, Anat Stemmer-Rachamimov, David J Kwiatkowski, Xandra O Breakefield

    Diterbitkan 2013-01-01
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  19. 19
    Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing.

    Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing. oleh Magdalena E Tyburczy, Kira A Dies, Jennifer Glass, Susana Camposano, Yvonne Chekaluk, Aaron R Thorner, Ling Lin, Darcy Krueger, David N Franz, Elizabeth A Thiele, Mustafa Sahin, David J Kwiatkowski

    Diterbitkan 2015-11-01
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  20. 20
    Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma.

    Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma. oleh Lana Hamieh, Toni K Choueiri, Barbara Ogórek, Damir Khabibullin, Daniel Rosebrock, Dimitri Livitz, Andre Fay, Jean-Christophe Pignon, David F McDermott, Neeraj Agarwal, Wenhua Gao, Sabina Signoretti, David J Kwiatkowski

    Diterbitkan 2018-09-01
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