Hasil Pencarian - Daniel Merk

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  1. 1
    A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics

    A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics oleh Laura Isigkeit, Apirat Chaikuad, Daniel Merk

    Diterbitkan 2022-04-01
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  2. 2
    Tribological Behavior of Hydrocarbons in Rolling Contact

    Tribological Behavior of Hydrocarbons in Rolling Contact oleh Daniel Merk, Thomas Koenig, Janine Fritz, Joerg W. H. Franke

    Diterbitkan 2024-06-01
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  3. 3
    Influence of Tribolayer on Rolling Bearing Fatigue Performed on an FE8 Test Rig—A Follow-up

    Influence of Tribolayer on Rolling Bearing Fatigue Performed on an FE8 Test Rig—A Follow-up oleh Joerg W. H. Franke, Janine Fritz, Thomas Koenig, Daniel Merk

    Diterbitkan 2023-03-01
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  4. 4
    Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

    Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics oleh Isabelle Meijer, Sabine Willems, Xiaomin Ni, Jan Heering, Apirat Chaikuad, Daniel Merk

    Diterbitkan 2020-10-01
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  5. 5
    Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists

    Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists oleh Moritz Helmstädter, Simone Schierle, Laura Isigkeit, Ewgenij Proschak, Julian Aurelio Marschner, Daniel Merk

    Diterbitkan 2022-09-01
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  6. 6
    Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms

    Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms oleh Apirat Chaikuad, Julius Pollinger, Michael Rühl, Xiaomin Ni, Whitney Kilu, Jan Heering, Daniel Merk

    Diterbitkan 2020-11-01
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  7. 7
    Publisher Correction: Scaffold hopping from natural products to synthetic mimetics by holistic molecular similarity

    Publisher Correction: Scaffold hopping from natural products to synthetic mimetics by holistic molecular similarity oleh Francesca Grisoni, Daniel Merk, Viviana Consonni, Jan A. Hiss, Sara Giani Tagliabue, Roberto Todeschini, Gisbert Schneider

    Diterbitkan 2018-09-01
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  8. 8
    Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro

    Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro oleh Pascal Heitel, Leonie Gellrich, Jan Heering, Tamara Goebel, Astrid Kahnt, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Daniel Merk

    Diterbitkan 2018-09-01
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  9. 9
    Synthetic Activators of Cell Migration Designed by Constructive Machine Learning

    Synthetic Activators of Cell Migration Designed by Constructive Machine Learning oleh Dr. Dominique Bruns, Dr. Daniel Merk, Dr. Karthiga Santhana Kumar, PD Dr. Martin Baumgartner, Prof. Dr. Gisbert Schneider

    Diterbitkan 2019-10-01
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  10. 10
    Nurr1 Modulation Mediates Neuroprotective Effects of Statins

    Nurr1 Modulation Mediates Neuroprotective Effects of Statins oleh Sabine Willems, Julian A. Marschner, Whitney Kilu, Giuseppe Faudone, Romy Busch, Silke Duensing‐Kropp, Jan Heering, Daniel Merk

    Diterbitkan 2022-06-01
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  11. 11
    Dual soluble epoxide hydrolase inhibitor – farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis

    Dual soluble epoxide hydrolase inhibitor – farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis oleh Md. Abdul Hye Khan, Benjamin Nolan, Anna Stavniichuk, Anna Stavniichuk, Daniel Merk, John D. Imig, John D. Imig

    Diterbitkan 2024-01-01
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  12. 12
    Development of Nurr1 agonists from amodiaquine by scaffold hopping and fragment growing

    Development of Nurr1 agonists from amodiaquine by scaffold hopping and fragment growing oleh Minh Sai, Emily C. Hank, Hin-Man Tai, Till Kasch, Max Lewandowski, Michelle Vincendeau, Julian A. Marschner, Daniel Merk

    Diterbitkan 2024-06-01
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  13. 13
    Allosteric modulation of the farnesoid X receptor by a small molecule

    Allosteric modulation of the farnesoid X receptor by a small molecule oleh Matthias Gabler, Jan Kramer, Jurema Schmidt, Julius Pollinger, Julia Weber, Astrid Kaiser, Frank Löhr, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Daniel Merk

    Diterbitkan 2018-05-01
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  14. 14
    Chemogenomics for NR1 nuclear hormone receptors

    Chemogenomics for NR1 nuclear hormone receptors oleh Laura Isigkeit, Espen Schallmayer, Romy Busch, Lorene Brunello, Amelie Menge, Lewis Elson, Susanne Müller, Stefan Knapp, Alexandra Stolz, Julian A. Marschner, Daniel Merk

    Diterbitkan 2024-06-01
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  15. 15
    Automated design of multi-target ligands by generative deep learning

    Automated design of multi-target ligands by generative deep learning oleh Laura Isigkeit, Tim Hörmann, Espen Schallmayer, Katharina Scholz, Felix F. Lillich, Johanna H. M. Ehrler, Benedikt Hufnagel, Jasmin Büchner, Julian A. Marschner, Jörg Pabel, Ewgenij Proschak, Daniel Merk

    Diterbitkan 2024-09-01
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  16. 16
    Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase‐1 Inhibitors by Automated De Novo Design

    Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase‐1 Inhibitors by Automated De Novo Design oleh Lukas Friedrich, Gino Cingolani, Ying‐Hui Ko, Mariaclara Iaselli, Morena Miciaccia, Maria Grazia Perrone, Konstantin Neukirch, Veronika Bobinger, Daniel Merk, Robert Klaus Hofstetter, Oliver Werz, Andreas Koeberle, Antonio Scilimati, Gisbert Schneider

    Diterbitkan 2021-08-01
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  17. 17
    Molecular tuning of farnesoid X receptor partial agonism

    Molecular tuning of farnesoid X receptor partial agonism oleh Daniel Merk, Sridhar Sreeramulu, Denis Kudlinzki, Krishna Saxena, Verena Linhard, Santosh L. Gande, Fabian Hiller, Christina Lamers, Ewa Nilsson, Anna Aagaard, Lisa Wissler, Niek Dekker, Krister Bamberg, Manfred Schubert-Zsilavecz, Harald Schwalbe

    Diterbitkan 2019-07-01
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  18. 18
    Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

    Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ oleh Tamara Göbel, Olaf Diehl, Jan Heering, Daniel Merk, Carlo Angioni, Sandra K. Wittmann, Estel.la Buscato, Ramona Kottke, Lilia Weizel, Tim Schader, Thorsten J. Maier, Gerd Geisslinger, Gerd Geisslinger, Manfred Schubert-Zsilavecz, Dieter Steinhilber, Ewgenij Proschak, Astrid S. Kahnt

    Diterbitkan 2019-03-01
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  19. 19
    Prospective de novo drug design with deep interactome learning

    Prospective de novo drug design with deep interactome learning oleh Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

    Diterbitkan 2024-04-01
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  20. 20
    Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3

    Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3 oleh Julia Steinmetz-Späh, Jianyang Liu, Rajkumar Singh, Maria Ekoff, Sanjaykumar Boddul, Xiao Tang, Filip Bergqvist, Helena Idborg, Pascal Heitel, Elin Rönnberg, Daniel Merk, Fredrik Wermeling, Jesper Z. Haeggström, Gunnar Nilsson, Dieter Steinhilber, Karin Larsson, Marina Korotkova, Per-Johan Jakobsson

    Diterbitkan 2022-12-01
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