Differential effects of HIV latency-reversing agents on T cell phenotype and function: implications for HIV cure by G. Clutton, N. Archin, Y. Xu, D.M. Margolis, N. Goonetilleke

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Single cell analysis of HIV latency reveals diverse proviral and host cell behaviour by E.P. Browne, T. Bradley, G. Ferrari, B.F. Haynes, D.M. Margolis

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SMAC mimetics are potent latency reversal agents with single agent and combination activity ex vivo by R.M. Dunham, G.C. Sampey, D.M. Irlbeck, E.P. Browne, D.M. Margolis

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SMAC mimetics reverse HIV latency by selective activation of the non-canonical NF-κB pathway by G.C. Sampey, D.M. Irlbeck, D.M. Margolis, R.M. Dunham, E.P. Brownel

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PP 3.11 – 00171 The chromatin insulator CTCF inhibits HIV gene expression by S. Burgos, S. Jefferys, J. Peterson, J. Parker, A. Manickam, J. Simon, D.M Margolis, E.P. Browne

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Sting agonist as a kick and kill agent to target the HIV reservoir by M. Mavigner, A.D. Brooks, A. Koblansky, C. Galardi, H. Madsen, D.M. Margolis, G. Silvestri, A. Chahroudi

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PP 2.9 – 00125 Impact of latency reversal agents on estrogen receptor alpha gene and protein expression by C. Ceriani, K.L. Lemu, A. Abeyta-Lopez, B. Allard, K.S. James, D.M. Margolis, N.M. Archin

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Induction of HIV from latency by a novel molecule by N.M. Archin, D. Boden, J. Kirchherr, B. Allard, K. Sholtis, J.D. Kuruc, G. Kraus, D.M. Margolis

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PP 1.4 – 00037 Histone decrotonylation uniquely regulates HIV-1 transcription and can be modulated to control HIV-1 latency by T.L. Simermeyer, D. Li, L.M. Wong, C. Aquino, Y. Tang, E.P. Browne, N.M. Archin, D.M. Margolis, G. Jiang

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Triazol-1-ol analogues as novel therapeutic leads towards reactivating and eradicating latent HIV-1 by manipulating SUMOylation of STAT5 by A. Bosque, A. Macedo, A. Spivak, C.L. Novis, L.J. Martins, M. Szaniawski, N.M. Archin, P.A. Luciw, D.M. Margolis, V. Planelles

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PP 4.14 – 00173 Antiretroviral therapy repairs CD4 T cell dysregulation in people living with HIV by A. Sponaugle, A.M. Weideman, J. Ranek, N. Archin, D.M. Margolis, B.G. Vincent, N. Stanley, G. Atassi, M.G. Hudgens, J. Eron, N. Goonetilleke, D. Kuritzkes, A. Adimora, A. Andrade

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CD8 depletion plus signaling of the non-canonical NF-kB pathway reverses latency in SIV-infected, ART-suppressed rhesus macaques by M. Mavigner, A.D. Brooks, G.K. Tharp, C. Mattingly, N. Schoof, T.H. Vanderford, S.E. Bosinger, G.C. Sampey, C. Galardi, R.M. Dunham, D.M. Margolis, G. Silvestri, A. Chahroudi

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The impact of vorinostat and AGS-004, a dendritic cell-based immunotherapy, on persistent HIV-1 Infection by C. Gay, J.D. Kuruc, S.D. Falcinelli, J. Warren, J.L. Kirchherr, K. Sholtis, B. Allard, E. Stuelke, A. Gamble, A. Plachco, I. Tcherapanova, J.J. Eron, N. Goonetilleke, M. DeBenedette, C.A. Nicolette, N.M. Archin, D.M. Margolis

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Preclinical development of a bispecific HIV x CD3 DART molecule that redirects T cells to kill HIV envelope (env)-expressing cells by J.L. Nordstrom, C. Nixon, J. Pickeral, C.h.-Y. Kao Lam, L. Liu, H. Li, S. Sharma, S. Gorlatov, F. Chen, K. Sampathkumar, G.D. Tomaras, S.M. Alam, P. Tsai, T. Morgan, P.T. Ho, B.F. Haynes, G. Ferrari, J.A. Sung, D.M. Margolis, J. Victor Garcia, S. Koenig

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OP 1.4 – 00053 Definitive evidence of a persistent HIV reservoir in human brain myeloid cells despite ART by Y. Tang, G. Jiang, M. Porrachia, C. Ignacio, L.M. Wong, D. Zhong, J. Du, B. Cotsakis, S. Maske, E. de la Parra Polina, T.L. Simermeyer, D. Li, B. Woodworth, J. Kirchherr, B. Allard, M. Clohosey, G.D. Whitehill, J.J. Eron, N.M. Archin, S.B. Joseph, K. Bar, A. Chaillon, S. Gianella, D.M. Margolis, G. Jiang

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