Hasil Pencarian - Chunwan Lu

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  1. 1
    JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer

    JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer oleh Chunwan Lu, Asif Talukder, Natasha M. Savage, Nagendra Singh, Kebin Liu

    Diterbitkan 2017-03-01
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  2. 2
    p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

    p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy oleh Chunwan Lu, Kebin Liu, John D Klement, Alyssa D Smith, Dafeng Yang, Darren D Browning

    Diterbitkan 2020-07-01
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  3. 3
    Type I Interferon Activates PD-1 Expression through Activation of the STAT1-IRF2 Pathway in Myeloid Cells

    Type I Interferon Activates PD-1 Expression through Activation of the STAT1-IRF2 Pathway in Myeloid Cells oleh Liyan Liang, Yingcui Yang, Kaidi Deng, Yanmin Wu, Yan Li, Liya Bai, Yinsong Wang, Chunwan Lu

    Diterbitkan 2024-07-01
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  4. 4
    The Wdr5-H3K4me3 Epigenetic Axis Regulates Pancreatic Tumor Immunogenicity and Immune Suppression

    The Wdr5-H3K4me3 Epigenetic Axis Regulates Pancreatic Tumor Immunogenicity and Immune Suppression oleh Kaidi Deng, Liyan Liang, Yingcui Yang, Yanmin Wu, Yan Li, Rongrong Zhang, Yulin Tian, Chunwan Lu

    Diterbitkan 2024-08-01
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  5. 5
    Editorial: The role of one-carbon metabolism in cancer progression, therapy, and resistance

    Editorial: The role of one-carbon metabolism in cancer progression, therapy, and resistance oleh Abhimanyu Thakur, Xin Hu, Xin Hu, Erhu Zhao, Erhu Zhao, Chunwan Lu, Yanqing Liu, Yashika Rustagi, Kui Zhang

    Diterbitkan 2023-09-01
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  6. 6
    H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

    H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells oleh Priscilla S. Redd, Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Gang Zhou, Takumi Kumai, Esteban Celis, Kebin Liu

    Diterbitkan 2018-09-01
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  7. 7
    Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

    Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes oleh Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Wei Xiao, Priscilla S. Redd, Asha Nayak-Kapoor, Gang Zhou, Kebin Liu

    Diterbitkan 2019-06-01
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  8. 8
    Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells

    Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells oleh Chunwan Lu, Dafeng Yang, Maria E. Sabbatini, Aaron H. Colby, Mark W. Grinstaff, Nicholas H. Oberlies, Cedric Pearce, Kebin Liu

    Diterbitkan 2018-02-01
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  9. 9
    DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function

    DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function oleh Yan Cao, Rongyang Li, Ming Shen, Chengyu Li, Yan Zou, Qiang Jiang, Shuo Liu, Chunwan Lu, Honglin Li, Honglin Liu, Yafei Cai

    Diterbitkan 2021-04-01
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  10. 10
    WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

    WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape oleh Jennifer L Waller, Chunwan Lu, Kebin Liu, John D Klement, Dafeng Yang, Zhuoqi Liu, Alyssa D Merting, Dakota Poschel, Thomas Albers, Huidong Shi

    Diterbitkan 2021-07-01
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  11. 11
    UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development.

    UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development. oleh Yafei Cai, Wenhu Pi, Satish Sivaprakasam, Xiaobin Zhu, Mingsheng Zhang, Jijun Chen, Levi Makala, Chunwan Lu, Jianchu Wu, Yong Teng, Betty Pace, Dorothy Tuan, Nagendra Singh, Honglin Li

    Diterbitkan 2015-11-01
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  12. 12
    G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

    G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes oleh Chunwan Lu, Kebin Liu, John D Klement, Dafeng Yang, Huidong Shi, Yolonda L Colson, Nicholas H Oberlies, Cedric J Pearce, Aaron H Colby, Mark W Grinstaff, Han-Fei Ding

    Diterbitkan 2022-01-01
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  13. 13
    Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis

    Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis oleh Mohammed L. Ibrahim, John D. Klement, Chunwan Lu, Priscilla S. Redd, Wei Xiao, Dafeng Yang, Darren D. Browning, Natasha M. Savage, Phillip J. Buckhaults, Herbert C. Morse, III, Kebin Liu

    Diterbitkan 2018-12-01
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  14. 14
    PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis

    PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis oleh Dakota B. Poschel, John D. Klement, Alyssa D. Merting, Chunwan Lu, Yang Zhao, Dafeng Yang, Wei Xiao, Huabin Zhu, Ponnala Rajeshwari, Michael Toscano, Kimya Jones, Amanda Barrett, Roni J. Bollag, Padraic G. Fallon, Huidong Shi, Kebin Liu

    Diterbitkan 2024-10-01
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