Hasil Pencarian - Christopher J Lord

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  1. 1
    Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions

    Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions oleh Christopher J Lord, Niall Quinn, Colm J Ryan

    Diterbitkan 2020-05-01
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  2. 2
    NLK is a novel therapeutic target for PTEN deficient tumour cells.

    NLK is a novel therapeutic target for PTEN deficient tumour cells. oleh Ana M Mendes-Pereira, Christopher J Lord, Alan Ashworth

    Diterbitkan 2012-01-01
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  3. 3
    Resistance to DNA repair inhibitors in cancer

    Resistance to DNA repair inhibitors in cancer oleh Joseph S. Baxter, Diana Zatreanu, Stephen J. Pettitt, Christopher J. Lord

    Diterbitkan 2022-11-01
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  4. 4
    Beyond DNA repair: the novel immunological potential of PARP inhibitors

    Beyond DNA repair: the novel immunological potential of PARP inhibitors oleh Roman M. Chabanon, Jean-Charles Soria, Christopher J. Lord, Sophie Postel-Vinay

    Diterbitkan 2019-03-01
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  5. 5
    Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer

    Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer oleh Agnieszka K. Witkiewicz, Sejin Chung, Rachel Brough, Paris Vail, Jorge Franco, Christopher J. Lord, Erik S. Knudsen

    Diterbitkan 2018-01-01
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  6. 6
    Opinion: PARP inhibitors in cancer—what do we still need to know?

    Opinion: PARP inhibitors in cancer—what do we still need to know? oleh Andrew J. Wicks, Dragomir B. Krastev, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Diterbitkan 2022-07-01
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  7. 7
    Longitudinal analysis of a secondary BRCA2 mutation using digital droplet PCR

    Longitudinal analysis of a secondary BRCA2 mutation using digital droplet PCR oleh Saira Khalique, Stephen J Pettitt, Ger Kelly, Nina Tunariu, Rachael Natrajan, Susana Banerjee, Christopher J Lord

    Diterbitkan 2020-01-01
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  8. 8
    Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets

    Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets oleh Dragomir B. Krastev, Stephen J. Pettitt, James Campbell, Feifei Song, Barbara E. Tanos, Stoyno S. Stoynov, Alan Ashworth, Christopher J. Lord

    Diterbitkan 2018-05-01
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  9. 9
    Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.

    Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. oleh Andrey A Parkhitko, Arashdeep Singh, Sharon Hsieh, Yanhui Hu, Richard Binari, Christopher J Lord, Sridhar Hannenhalli, Colm J Ryan, Norbert Perrimon

    Diterbitkan 2021-02-01
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  10. 10
    Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2018-01-01
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  11. 11
    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2017-01-01
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  12. 12
    CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2016-01-01
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  13. 13
    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2016-01-01
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  14. 14
    Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancer.

    Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancer. oleh Louise J Barber, Juan M Rosa Rosa, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Costas Mitsopoulos, David Sims, Jarle Hakas, Marketa Zvelebil, Christopher J Lord, Alan Ashworth

    Diterbitkan 2011-01-01
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  15. 15
    A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity.

    A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity. oleh Stephen J Pettitt, Farah L Rehman, Ilirjana Bajrami, Rachel Brough, Fredrik Wallberg, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Lina Chen, James Campbell, Christopher J Lord, Alan Ashworth

    Diterbitkan 2013-01-01
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  16. 16
    Correction: A Modified Method for Whole Exome Resequencing from Minimal Amounts of Starting DNA.

    Correction: A Modified Method for Whole Exome Resequencing from Minimal Amounts of Starting DNA. oleh Iwanka Kozarewa, Juan Manuel Rosa-Rosa, Christopher P. Wardell, Brian A. Walker, Kerry Fenwick, Ioannis Assiotis, Costas Mitsopoulos, Marketa Zvelebil, Gareth J. Morgan, Alan Ashworth, Christopher J. Lord

    Diterbitkan 2012-01-01
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  17. 17
    A modified method for whole exome resequencing from minimal amounts of starting DNA.

    A modified method for whole exome resequencing from minimal amounts of starting DNA. oleh Iwanka Kozarewa, Juan Manuel Rosa-Rosa, Christopher P Wardell, Brian A Walker, Kerry Fenwick, Ioannis Assiotis, Costas Mitsopoulos, Marketa Zvelebil, Gareth J Morgan, Alan Ashworth, Christopher J Lord

    Diterbitkan 2012-01-01
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  18. 18
    Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency

    Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency oleh Ilirjana Bajrami, Callum Walker, Dragomir B. Krastev, Daniel Weekes, Feifei Song, Andrew J. Wicks, John Alexander, Syed Haider, Rachel Brough, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Diterbitkan 2021-11-01
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  19. 19
    Integrated functional, gene expression and genomic analysis for the identification of cancer targets.

    Integrated functional, gene expression and genomic analysis for the identification of cancer targets. oleh Elizabeth Iorns, Christopher J Lord, Anita Grigoriadis, Sarah McDonald, Kerry Fenwick, Alan Mackay, Charles A Mein, Rachael Natrajan, Kay Savage, Narinder Tamber, Jorge S Reis-Filho, Nicholas C Turner, Alan Ashworth

    Diterbitkan 2009-01-01
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  20. 20
    Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

    Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7 oleh Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Diterbitkan 2024-02-01
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