Hasil Pencarian - Christophe Pannecouque

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  1. 1
    Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

    Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years oleh Chunlin Zhuang, Christophe Pannecouque, Erik De Clercq, Fener Chen

    Diterbitkan 2020-06-01
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  2. 2
    Amino acid derivatives. Part 6. New analogues of the angiotensin-converting enzyme 'Captopril'. Synthesis and anti-HIV activity

    Amino acid derivatives. Part 6. New analogues of the angiotensin-converting enzyme 'Captopril'. Synthesis and anti-HIV activity oleh Najim A. Al-Masoudi, Nawar S. Hamad, Shahid Hameed, Christophe Pannecouque

    Diterbitkan 2010-10-01
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  3. 3
    Discovery of Biphenyl-Substituted Diarylpyrimidines as New Non-Nucleoside HIV-1 Reverse Transcripttase Inhibitors

    Discovery of Biphenyl-Substituted Diarylpyrimidines as New Non-Nucleoside HIV-1 Reverse Transcripttase Inhibitors oleh Kaijun Jin, Ge Meng, Fen-Er Chen, Erik De Clercq, Christophe Pannecouque

    Diterbitkan 2017-10-01
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  4. 4
    Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

    Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity oleh Sampad Jana, Shabina Iram, Joice Thomas, Muhammad Qasim Hayat, Christophe Pannecouque, Wim Dehaen

    Diterbitkan 2017-02-01
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  5. 5
    Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability

    Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability oleh Ya-Li Sang, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

    Diterbitkan 2023-07-01
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  6. 6
    Structure-based design of novel heterocycle-substituted ATDP analogs as non-nucleoside reverse transcriptase inhibitors with improved selectivity and solubility

    Structure-based design of novel heterocycle-substituted ATDP analogs as non-nucleoside reverse transcriptase inhibitors with improved selectivity and solubility oleh Li-Min Zhao, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

    Diterbitkan 2023-12-01
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  7. 7
    Scaffold Hopping in Discovery of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: From CH(CN)-DABOs to CH(CN)-DAPYs

    Scaffold Hopping in Discovery of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: From CH(CN)-DABOs to CH(CN)-DAPYs oleh Ting-Ting Li, Christophe Pannecouque, Erik De Clercq, Chun-Lin Zhuang, Fen-Er Chen

    Diterbitkan 2020-03-01
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  8. 8
    Designing Novel Hydrazinecarbothioamides as Potential HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

    Designing Novel Hydrazinecarbothioamides as Potential HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors oleh Hong Yin, Zhengyong Wan, Ge Meng, Fen-Er Chen, Erik De Clercq, and Christophe Pannecouque

    Diterbitkan 2017-10-01
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  9. 9
    Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

    Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors oleh Kaijun Jin, Minjie Liu, Chunlin Zhuang, Erik De Clercq, Christophe Pannecouque, Ge Meng, Fener Chen

    Diterbitkan 2020-02-01
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  10. 10
    Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy

    Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy oleh Yuan Lei, Sheng Han, Yang Yang, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, Fen-Er Chen

    Diterbitkan 2020-02-01
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  11. 11
    Synthesis and primary antiviral activity evaluation of 3-hydrazono-5-nitro-2-indolinone derivatives

    Synthesis and primary antiviral activity evaluation of 3-hydrazono-5-nitro-2-indolinone derivatives oleh Nalan Terzioglu, Nilgün Karali, Aysel Gürsoy, Christophe Pannecouque, Pieter Leysen, Jan Paeshuyse, Johan Neyts, Erik De Clercq

    Diterbitkan 2005-11-01
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  12. 12
    Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variants

    Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variant... oleh Zhao Wang, Heng Zhang, Zhen Gao, Zihao Sang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

    Diterbitkan 2024-03-01
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  13. 13
    Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood–Brain Barrier System

    Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood–Brain Barrier System oleh Antonios Fikatas, Jonas Dehairs, Sam Noppen, Jordi Doijen, Frank Vanderhoydonc, Eef Meyen, Johannes V. Swinnen, Christophe Pannecouque, Dominique Schols

    Diterbitkan 2021-11-01
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  14. 14
    Identification of Novel Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors by Exploring the Primer Grip Region

    Identification of Novel Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors by Exploring the Primer Grip Region oleh Tao Zhang, Zhongxia Zhou, Fabao Zhao, Zihao Sang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

    Diterbitkan 2022-11-01
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  15. 15
    Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors

    Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors oleh Yang Yang, Dongwei Kang, Laura A Nguyen, Zachary B Smithline, Christophe Pannecouque, Peng Zhan, Xinyong Liu, Thomas A Steitz

    Diterbitkan 2018-07-01
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  16. 16
    The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition.

    The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition. oleh Kathrin Reiser, Leen Mathys, Sophie Curbo, Christophe Pannecouque, Sam Noppen, Sandra Liekens, Lars Engman, Mathias Lundberg, Jan Balzarini, Anna Karlsson

    Diterbitkan 2016-01-01
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  17. 17
    Structure-Based Design of Novel Thiazolone[3,2-<i>a</i>]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy

    Structure-Based Design of Novel Thiazolone[3,2-<i>a</i>]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy oleh Xuan-De Zhu, Angela Corona, Stefania Maloccu, Enzo Tramontano, Shuai Wang, Christophe Pannecouque, Erik De Clercq, Ge Meng, Fen-Er Chen

    Diterbitkan 2024-05-01
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  18. 18
    Development of fluorine-substituted NH2-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability

    Development of fluorine-substituted NH2-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability oleh Xin Jin, Shuai Wang, Limin Zhao, Wenjuan Huang, Yinxiang Zhang, Christophe Pannecouque, Erik De Clercq, Ge Meng, Huri Piao, Fener Chen

    Diterbitkan 2023-03-01
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  19. 19
    Synthesis of Novel Derivatives of 4-Amino-3-(2-Furyl)-5-Mercapto-1,2,4-Triazole as Potential HIV-1 NNRTIs

    Synthesis of Novel Derivatives of 4-Amino-3-(2-Furyl)-5-Mercapto-1,2,4-Triazole as Potential HIV-1 NNRTIs oleh Erik De Clercq, Myriam Witvrouw, Christophe Pannecouque, Wenfang Xu, Zhong Li, Defeng Wang, Yuan Cao, Xianchao Cheng, Xinyong Liu, Jingde Wu

    Diterbitkan 2007-08-01
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  20. 20
    1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

    1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity oleh Jenny Desantis, Serena Massari, Angela Corona, Andrea Astolfi, Stefano Sabatini, Giuseppe Manfroni, Deborah Palazzotti, Violetta Cecchetti, Christophe Pannecouque, Enzo Tramontano, Oriana Tabarrini

    Diterbitkan 2020-03-01
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