Hasil Pencarian - Christian B. Lessard

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  1. 1
    γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).

    γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP). oleh Christian B Lessard, Barbara A Cottrell, Hiroko Maruyama, Suraj Suresh, Todd E Golde, Edward H Koo

    Diterbitkan 2015-01-01
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  2. 2
    γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not

    γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not oleh Christian B. Lessard, Edgardo Rodriguez, Thomas B. Ladd, Lisa M. Minter, Barbara A. Osborne, Lucio Miele, Todd E. Golde, Yong Ran

    Diterbitkan 2020-05-01
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  3. 3
    γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

    γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct oleh Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde

    Diterbitkan 2017-05-01
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  4. 4
    Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

    Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph oleh Lorenza Magno, Christian B. Lessard, Marta Martins, Verena Lang, Pedro Cruz, Yasmine Asi, Matilda Katan, Jamie Bilsland, Tammaryn Lashley, Paramita Chakrabarty, Todd E. Golde, Paul J. Whiting

    Diterbitkan 2019-02-01
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  5. 5
    High‐affinity interactions and signal transduction between Aβ oligomers and TREM2

    High‐affinity interactions and signal transduction between Aβ oligomers and TREM2 oleh Christian B Lessard, Samuel L Malnik, Yingyue Zhou, Thomas B Ladd, Pedro E Cruz, Yong Ran, Thomas E Mahan, Paramita Chakrabaty, David M Holtzman, Jason D Ulrich, Marco Colonna, Todd E Golde

    Diterbitkan 2018-11-01
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  6. 6
    Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways

    Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways oleh Kristen R. Ibanez, Karen N. McFarland, Jennifer Phillips, Mariet Allen, Christian B. Lessard, Lillian Zobel, Elsa Gonzalez De La Cruz, Shivani Shah, Quan Vo, Xue Wang, Zachary Quicksall, Daniel Ryu, Cory Funk, Nilüfer Ertekin-Taner, Stefan Prokop, Todd E. Golde, Paramita Chakrabarty

    Diterbitkan 2022-07-01
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