A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway oleh Jeongeun Park, Haiying Zhang, Hyun Jung Kwak, Changdev Gorakshnath Gadhe, Yeomyeong Kim, Hyejeong Kim, Minyoung Noh, Dongyun Shin, Sang-Jun Ha, Young-Guen Kwon