Hasil Pencarian - Boris N Kholodenko

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  1. 1
    Drug Resistance Resulting from Kinase Dimerization Is Rationalized by Thermodynamic Factors Describing Allosteric Inhibitor Effects

    Drug Resistance Resulting from Kinase Dimerization Is Rationalized by Thermodynamic Factors Describing Allosteric Inhibitor Effects oleh Boris N. Kholodenko

    Diterbitkan 2015-09-01
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  2. 2
    Polyubiquitin chain assembly and organisation determine the dynamics of protein activation and degradation

    Polyubiquitin chain assembly and organisation determine the dynamics of protein activation and degradation oleh Lan K. Nguyen, Maciej eDobrzynski, Dirk eFey, Boris N Kholodenko, Boris N Kholodenko, Boris N Kholodenko

    Diterbitkan 2014-01-01
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  3. 3
    Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.

    Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration. oleh Tapesh Santra, Walter Kolch, Boris N Kholodenko

    Diterbitkan 2014-02-01
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  4. 4
    Performance of objective functions and optimisation procedures for parameter estimation in system biology models

    Performance of objective functions and optimisation procedures for parameter estimation in system biology models oleh Andrea Degasperi, Dirk Fey, Boris N. Kholodenko

    Diterbitkan 2017-08-01
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  5. 5
    Positional information generated by spatially distributed signaling cascades.

    Positional information generated by spatially distributed signaling cascades. oleh Javier Muñoz-García, Zoltan Neufeld, Boris N Kholodenko

    Diterbitkan 2009-03-01
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  6. 6
    Versatility of cooperative transcriptional activation: a thermodynamical modeling analysis for greater-than-additive and less-than-additive effects.

    Versatility of cooperative transcriptional activation: a thermodynamical modeling analysis for greater-than-additive and less-than-additive effects. oleh Till D Frank, Aimée M Carmody, Boris N Kholodenko

    Diterbitkan 2012-01-01
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  7. 7
    Crosstalk and signalling switches in mitogen-activated protein kinase cascades

    Crosstalk and signalling switches in mitogen-activated protein kinase cascades oleh Dirk eFey, David R Croucher, Walter eKolch, Boris N Kholodenko

    Diterbitkan 2012-09-01
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  8. 8
    Evaluating strategies to normalise biological replicates of Western blot data.

    Evaluating strategies to normalise biological replicates of Western blot data. oleh Andrea Degasperi, Marc R Birtwistle, Natalia Volinsky, Jens Rauch, Walter Kolch, Boris N Kholodenko

    Diterbitkan 2014-01-01
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  9. 9
    Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system.

    Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system. oleh Lan K Nguyen, Javier Muñoz-García, Helene Maccario, Aaron Ciechanover, Walter Kolch, Boris N Kholodenko

    Diterbitkan 2011-12-01
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  10. 10
    The APC Network Regulates the Removal of Mutated Cells from Colonic Crypts

    The APC Network Regulates the Removal of Mutated Cells from Colonic Crypts oleh Je-Hoon Song, David J. Huels, Rachel A. Ridgway, Owen J. Sansom, Boris N. Kholodenko, Walter Kolch, Kwang-Hyun Cho

    Diterbitkan 2014-04-01
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  11. 11
    Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells

    Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells oleh Thomas Sevrin, Hiroaki Imoto, Sarah Robertson, Nora Rauch, Uscinnia Dyn’ko, Katerina Koubova, Kieran Wynne, Walter Kolch, Oleksii S. Rukhlenko, Boris N. Kholodenko

    Diterbitkan 2024-09-01
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  12. 12
    SARAH Domain-Mediated MST2-RASSF Dimeric Interactions.

    SARAH Domain-Mediated MST2-RASSF Dimeric Interactions. oleh Goar Sánchez-Sanz, Bartłomiej Tywoniuk, David Matallanas, David Romano, Lan K Nguyen, Boris N Kholodenko, Edina Rosta, Walter Kolch, Nicolae-Viorel Buchete

    Diterbitkan 2016-10-01
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  13. 13
    Frequency modulation of ERK activation dynamics rewires cell fate

    Frequency modulation of ERK activation dynamics rewires cell fate oleh Hyunryul Ryu, Minhwan Chung, Maciej Dobrzyński, Dirk Fey, Yannick Blum, Sung Sik Lee, Matthias Peter, Boris N Kholodenko, Noo Li Jeon, Olivier Pertz

    Diterbitkan 2016-04-01
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  14. 14
    A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression

    A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression oleh Hiroaki Imoto, Nora Rauch, Ashish J. Neve, Fahimeh Khorsand, Martina Kreileder, Leonidas G. Alexopoulos, Jens Rauch, Mariko Okada, Boris N. Kholodenko, Oleksii S. Rukhlenko

    Diterbitkan 2023-08-01
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  15. 15
    Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration

    Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration oleh Alfonso Bolado-Carrancio, Oleksii S Rukhlenko, Elena Nikonova, Mikhail A Tsyganov, Anne Wheeler, Amaya Garcia-Munoz, Walter Kolch, Alex von Kriegsheim, Boris N Kholodenko

    Diterbitkan 2020-07-01
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  16. 16
    Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation.

    Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation. oleh Malgorzata Milewska, David Romano, Ana Herrero, Maria Luisa Guerriero, Marc Birtwistle, Franz Quehenberger, Stefan Hatzl, Boris N Kholodenko, Oreste Segatto, Walter Kolch, Armin Zebisch

    Diterbitkan 2015-01-01
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  17. 17
    Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor.

    Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor. oleh Keesha E Erickson, Oleksii S Rukhlenko, Md Shahinuzzaman, Kalina P Slavkova, Yen Ting Lin, Ryan Suderman, Edward C Stites, Marian Anghel, Richard G Posner, Dipak Barua, Boris N Kholodenko, William S Hlavacek

    Diterbitkan 2019-01-01
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  18. 18
    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis oleh Sujoy Chatterjee, Shivraj M. Yabaji, Oleksii S. Rukhlenko, Bidisha Bhattacharya, Emily Waligurski, Nandini Vallavoju, Somak Ray, Boris N. Kholodenko, Lauren E. Brown, Aaron B. Beeler, Alexander R. Ivanov, Lester Kobzik, John A. Porco, Jr., Igor Kramnik

    Diterbitkan 2021-08-01
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  19. 19
    Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

    Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D oleh Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

    Diterbitkan 2020-01-01
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