Hasil Pencarian - Benoit Laleu

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  1. 1
    Current Pipeline of Antimalarial Therapies

    Current Pipeline of Antimalarial Therapies oleh Benoît Laleu

    Diterbitkan 2017-10-01
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  2. 2
    Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni

    Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni oleh Valérian Pasche, Benoît Laleu, Jennifer Keiser

    Diterbitkan 2018-05-01
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  3. 3
    ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development

    ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development oleh Siddhartha Mishra, Nipun Malhotra, Benoît Laleu, Soumyananda Chakraborti, Manickam Yogavel, Amit Sharma

    Diterbitkan 2024-07-01
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  4. 4
    Actives from MMV Open Access Boxes? A suggested way forward.

    Actives from MMV Open Access Boxes? A suggested way forward. oleh Kirandeep Samby, Paul A Willis, Jeremy N Burrows, Benoît Laleu, Peter J H Webborn

    Diterbitkan 2021-04-01
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  5. 5
    Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum

    Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum oleh Camilla Valente Pires, Debora Cassandra, Shulin Xu, Benoit Laleu, Jeremy N. Burrows, John H. Adams

    Diterbitkan 2024-03-01
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  6. 6
    Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates

    Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates oleh Jian Liang Low, Mu-Lu Wu, Dinah Binte Aziz, Benoît Laleu, Thomas Dick, Thomas Dick

    Diterbitkan 2017-08-01
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  7. 7
    Novel Compound MMV1804559 from the Global Health Priority Box Exhibits In Vitro and In Vivo Activity against <i>Madurella mycetomatis</i>

    Novel Compound MMV1804559 from the Global Health Priority Box Exhibits In Vitro and In Vivo Activity against <i>Madurella mycetomatis</i> oleh Jingyi Ma, Kimberly Eadie, Marij Schippers, Ahmed Fahal, Benoît Laleu, Annelies Verbon, Wendy W. J. van de Sande

    Diterbitkan 2024-06-01
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  8. 8
    Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development.

    Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development. oleh Yogavel Manickam, Nipun Malhotra, Siddhartha Mishra, Palak Babbar, Abhishek Dusane, Benoît Laleu, Valeria Bellini, Mohamed-Ali Hakimi, Alexandre Bougdour, Amit Sharma

    Diterbitkan 2022-03-01
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  9. 9
    Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm

    Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm oleh Sarah Preston, Yaqing Jiao, Abdul Jabbar, Sean L. McGee, Benoît Laleu, Paul Willis, Timothy N.C. Wells, Robin B. Gasser

    Diterbitkan 2016-12-01
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  10. 10
    Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

    Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis oleh Manickam Yogavel, Alexandre Bougdour, Siddhartha Mishra, Nipun Malhotra, Jyoti Chhibber-Goel, Valeria Bellini, Karl Harlos, Benoît Laleu, Mohamed-Ali Hakimi, Amit Sharma

    Diterbitkan 2023-02-01
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  11. 11
    Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.

    Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. oleh Manickam Yogavel, Alexandre Bougdour, Siddhartha Mishra, Nipun Malhotra, Jyoti Chhibber-Goel, Valeria Bellini, Karl Harlos, Benoît Laleu, Mohamed-Ali Hakimi, Amit Sharma

    Diterbitkan 2023-02-01
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  12. 12
    Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.

    Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. oleh Wilson Lim, Youri Melse, Mickey Konings, Hung Phat Duong, Kimberly Eadie, Benoît Laleu, Benjamin Perry, Matthew H Todd, Jean-Robert Ioset, Wendy W J van de Sande

    Diterbitkan 2018-04-01
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  13. 13
    Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

    Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus oleh Yaqing Jiao, Sarah Preston, Anson V. Koehler, Andreas J. Stroehlein, Bill C. H. Chang, Kaylene J. Simpson, Karla J. Cowley, Michael J. Palmer, Benoît Laleu, Timothy N. C. Wells, Abdul Jabbar, Robin B. Gasser

    Diterbitkan 2017-07-01
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  14. 14
    Preliminary Structure–Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of <i>Trypanosoma brucei brucei</i>

    Preliminary Structure–Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of <i>Trypanosoma brucei brucei</i> oleh Darline Dize, Rolland Bantar Tata, Rodrigue Keumoe, Rufin Marie Kouipou Toghueo, Mariscal Brice Tchatat, Cyrille Ngansop Njanpa, Vianey Claire Tchuenguia, Lauve Tchokouaha Yamthe, Patrick Valere Tsouh Fokou, Benoît Laleu, James Duffy, Ozlem Tastan Bishop, Fabrice Fekam Boyom

    Diterbitkan 2022-10-01
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  15. 15
    Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

    Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus oleh Yaqing Jiao, Sarah Preston, Hongjian Song, Abdul Jabbar, Yuxiu Liu, Jonathan Baell, Andreas Hofmann, Dana Hutchinson, Tao Wang, Anson V. Koehler, Gillian M. Fisher, Katherine T. Andrews, Benoît Laleu, Michael J. Palmer, Jeremy N. Burrows, Timothy N. C. Wells, Qingmin Wang, Robin B. Gasser

    Diterbitkan 2017-05-01
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  16. 16
    Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out

    Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a... oleh Koen J. Dechering, Martijn Timmerman, Kim Rensen, Karin M.J. Koolen, Saman Honarnejad, Martijn W. Vos, Tonnie Huijs, Rob W.M. Henderson, Elodie Chenu, Benoît Laleu, Bailey C. Montefiore, Matthew D. Segall, James E.J. Mills, Eric M. Guantai, James Duffy, Maëlle Duffey

    Diterbitkan 2022-09-01
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  17. 17
    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum oleh Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G. Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Marcus C. S. Lee

    Diterbitkan 2023-05-01
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  18. 18
    Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

    Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation oleh Selina Bopp, Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S. Nasamu, Allison R. Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M. Early, Amanda K. Lukens, Danny Milner, Jeremy Furtado, Francisco-Javier Gamo, Elizabeth A. Winzeler, Sarah K. Volkman, Maëlle Duffey, Benoît Laleu, David A. Fidock, Susan Wyllie, Jacquin C. Niles, Dyann F. Wirth

    Diterbitkan 2023-03-01
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  19. 19
    Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease

    Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease oleh Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White

    Diterbitkan 2023-08-01
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  20. 20
    Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. oleh Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Pietro Alano, Aintzane Alday, Yesmalie Alemán Resto, Aishah Alsibaee, Ainhoa Alzualde, Katherine T Andrews, Simon V Avery, Vicky M Avery, Lawrence Ayong, Mark Baker, Stephen Baker, Choukri Ben Mamoun, Sangeeta Bhatia, Quentin Bickle, Lotfi Bounaadja, Tana Bowling, Jürgen Bosch, Lauren E Boucher, Fabrice F Boyom, Jose Brea, Marian Brennan, Audrey Burton, Conor R Caffrey, Grazia Camarda, Manuela Carrasquilla, Dee Carter, Maria Belen Cassera, Ken Chih-Chien Cheng, Worathad Chindaudomsate, Anthony Chubb, Beatrice L Colon, Daisy D Colón-López, Yolanda Corbett, Gregory J Crowther, Noemi Cowan, Sarah D'Alessandro, Na Le Dang, Michael Delves, Joseph L DeRisi, Alan Y Du, Sandra Duffy, Shimaa Abd El-Salam El-Sayed, Michael T Ferdig, José A Fernández Robledo, David A Fidock, Isabelle Florent, Patrick V T Fokou, Ani Galstian, Francisco Javier Gamo, Suzanne Gokool, Ben Gold, Todd Golub, Gregory M Goldgof, Rajarshi Guha, W Armand Guiguemde, Nil Gural, R Kiplin Guy, Michael A E Hansen, Kirsten K Hanson, Andrew Hemphill, Rob Hooft van Huijsduijnen, Takaaki Horii, Paul Horrocks, Tyler B Hughes, Christopher Huston, Ikuo Igarashi, Katrin Ingram-Sieber, Maurice A Itoe, Ajit Jadhav, Amornrat Naranuntarat Jensen, Laran T Jensen, Laran T Jensen, Rays H Y Jiang, Annette Kaiser, Jennifer Keiser, Thomas Ketas, Sebastien Kicka, Sunyoung Kim, Kiaran Kirk, Vidya P Kumar, Dennis E Kyle, Maria Jose Lafuente, Scott Landfear, Nathan Lee, Sukjun Lee, Adele M Lehane, Fengwu Li, David Little, Liqiong Liu, Manuel Llinás, Maria I Loza, Aristea Lubar, Leonardo Lucantoni, Isabelle Lucet, Louis Maes, Dalu Mancama, Nuha R Mansour, Sandra March, Sheena McGowan, Iset Medina Vera, Stephan Meister, Luke Mercer, Jordi Mestres, Alvine N Mfopa, Raj N Misra, Seunghyun Moon, John P Moore, Francielly Morais Rodrigues da Costa, Joachim Müller, Arantza Muriana, Stephen Nakazawa Hewitt, Bakela Nare, Carl Nathan, Nathalie Narraidoo, Sujeevi Nawaratna, Kayode K Ojo, Diana Ortiz, Gordana Panic, George Papadatos, Silvia Parapini, Kailash Patra, Ngoc Pham, Sarah Prats, David M Plouffe, Sally-Ann Poulsen, Anupam Pradhan, Celia Quevedo, Ronald J Quinn, Christopher A Rice, Mohamed Abdo Rizk, Andrea Ruecker, Robert St Onge, Rafaela Salgado Ferreira, Jasmeet Samra, Natalie G Robinett, Ulrich Schlecht, Marjorie Schmitt, Filipe Silva Villela, Francesco Silvestrini, Robert Sinden, Dennis A Smith, Thierry Soldati, Andreas Spitzmüller, Serge Maximilian Stamm, David J Sullivan, William Sullivan, Sundari Suresh, Brian M Suzuki, Yo Suzuki, S Joshua Swamidass, Donatella Taramelli, Lauve R Y Tchokouaha, Anjo Theron, David Thomas, Kathryn F Tonissen, Simon Townson, Abhai K Tripathi, Valentin Trofimov, Kenneth O Udenze, Imran Ullah, Cindy Vallieres, Edgar Vigil, Joseph M Vinetz, Phat Voong Vinh, Hoan Vu, Nao-Aki Watanabe, Kate Weatherby, Pamela M White, Andrew F Wilks, Elizabeth A Winzeler, Edward Wojcik, Melanie Wree, Wesley Wu, Naoaki Yokoyama, Paul H A Zollo, Nada Abla, Benjamin Blasco, Jeremy Burrows, Benoît Laleu, Didier Leroy, Thomas Spangenberg, Timothy Wells, Paul A Willis

    Diterbitkan 2016-07-01
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