Hasil Pencarian - Benjamin Haley

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  1. 1
    A versatile, high-efficiency platform for CRISPR-based gene activation

    A versatile, high-efficiency platform for CRISPR-based gene activation oleh Amy J. Heidersbach, Kristel M. Dorighi, Javier A. Gomez, Ashley M. Jacobi, Benjamin Haley

    Diterbitkan 2023-02-01
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  2. 2
    Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

    Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs oleh Nisebita Sahu, Jean-Philippe Stephan, Darlene Dela Cruz, Mark Merchant, Benjamin Haley, Richard Bourgon, Marie Classon, Jeff Settleman

    Diterbitkan 2016-08-01
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  3. 3
    A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC.

    A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC. oleh Nicholas Dompe, Christiaan Klijn, Sara A Watson, Katherine Leng, Jenna Port, Trinna Cuellar, Colin Watanabe, Benjamin Haley, Richard Neve, Marie Evangelista, David Stokoe

    Diterbitkan 2018-01-01
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  4. 4
    Non-canonical reader modules of BAZ1A promote recovery from DNA damage

    Non-canonical reader modules of BAZ1A promote recovery from DNA damage oleh Mariano Oppikofer, Meredith Sagolla, Benjamin Haley, Hui-Min Zhang, Sarah K. Kummerfeld, Jawahar Sudhamsu, E. Megan Flynn, Tianyi Bai, Jennifer Zhang, Claudio Ciferri, Andrea G. Cochran

    Diterbitkan 2017-10-01
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  5. 5
    S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis

    S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis oleh Wenlin Yuan, Leonard D. Goldstein, Steffen Durinck, Ying-Jiun Chen, Thong T. Nguyen, Noelyn M. Kljavin, Ethan S. Sokol, Eric W. Stawiski, Benjamin Haley, James Ziai, Zora Modrusan, Somasekar Seshagiri

    Diterbitkan 2019-12-01
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  6. 6
    1130 Design and characterization of novel TLR7-selective ligands with an automated screening platform

    1130 Design and characterization of novel TLR7-selective ligands with an automated screening platform oleh Siri Tähtinen, Ira Mellman, Christopher Kemball, Diamanda Rigas, Emily Freund, Rebecca Leylek, Ann-Jay Tong, Anna-Maria Herzner, Shirley Ng Palace, Sara Wichner, Craig Blanchette, Benjamin Haley, Lélia Delamarre

    Diterbitkan 2023-11-01
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  7. 7
    Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components

    Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components oleh Honglin Chen, Steffen Durinck, Hetal Patel, Oded Foreman, Kathryn Mesh, Jeffrey Eastham, Roger Caothien, Robert J. Newman, Merone Roose-Girma, Spyros Darmanis, Soren Warming, Annalisa Lattanzi, Yuxin Liang, Benjamin Haley

    Diterbitkan 2022-12-01
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  8. 8
    EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

    EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation oleh Ariel Pribluda, Anneleen Daemen, Anthony Nelson Lima, Xi Wang, Marc Hafner, Chungkee Poon, Zora Modrusan, Anand Kumar Katakam, Oded Foreman, Jefferey Eastham, Jefferey Hung, Benjamin Haley, Julia T Garcia, Erica L Jackson, Melissa R Junttila

    Diterbitkan 2022-08-01
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  9. 9
    Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

    Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice oleh Janet Lau, Jeanne Cheung, Armando Navarro, Steve Lianoglou, Benjamin Haley, Klara Totpal, Laura Sanders, Hartmut Koeppen, Patrick Caplazi, Jacqueline McBride, Henry Chiu, Rebecca Hong, Jane Grogan, Vincent Javinal, Robert Yauch, Bryan Irving, Marcia Belvin, Ira Mellman, Jeong M. Kim, Maike Schmidt

    Diterbitkan 2017-02-01
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  10. 10
    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins oleh Alexandra M Whiteley, Miguel A Prado, Ivan Peng, Alexander R Abbas, Benjamin Haley, Joao A Paulo, Mike Reichelt, Anand Katakam, Meredith Sagolla, Zora Modrusan, Dong Yun Lee, Merone Roose-Girma, Donald S Kirkpatrick, Brent S McKenzie, Steven P Gygi, Daniel Finley, Eric J Brown

    Diterbitkan 2017-09-01
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  11. 11
    Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity

    Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity oleh Riccardo Guidi, Christopher Wedeles, Daqi Xu, Krzysztof Kolmus, Sarah E. Headland, Grace Teng, Joseph Guillory, Yi Jimmy Zeng, Tommy K. Cheung, Subhra Chaudhuri, Zora Modrusan, Yuxin Liang, Stuart Horswell, Benjamin Haley, Sascha Rutz, Christopher Rose, Yvonne Franke, Donald S. Kirkpatrick, Jason A. Hackney, Mark S. Wilson

    Diterbitkan 2023-12-01
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  12. 12
    Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors

    Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors oleh Kristin M. Zimmerman Savill, Brian B. Lee, Jason Oeh, Jie Lin, Eva Lin, Wei-Jen Chung, Amy Young, Wennie Chen, Monika Miś, Kathryn Mesh, Jeffrey Eastham, Florian Gnad, Zhaoshi Jiang, Eric W. Stawiski, Benjamin Haley, Anneleen Daemen, Xiaojing Wang, Hartmut Koeppen, Zora Modrusan, Scott E. Martin, Deepak Sampath, Kui Lin

    Diterbitkan 2022-04-01
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  13. 13
    CRAF dimerization with ARAF regulates KRAS-driven tumor growth

    CRAF dimerization with ARAF regulates KRAS-driven tumor growth oleh Avinashnarayan Venkatanarayan, Jason Liang, Ivana Yen, Frances Shanahan, Benjamin Haley, Lilian Phu, Erik Verschueren, Trent B. Hinkle, David Kan, Ehud Segal, Jason E. Long, Tony Lima, Nicholas P.D. Liau, Jawahar Sudhamsu, Jason Li, Christiaan Klijn, Robert Piskol, Melissa R. Junttila, Andrey S. Shaw, Mark Merchant, Matthew T. Chang, Donald S. Kirkpatrick, Shiva Malek

    Diterbitkan 2022-02-01
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  14. 14
    Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance

    Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance oleh Yexuan Deng, Sarah T. Diepstraten, Margaret A. Potts, Göknur Giner, Stephanie Trezise, Ashley P. Ng, Gerry Healey, Serena R. Kane, Amali Cooray, Kira Behrens, Amy Heidersbach, Andrew J. Kueh, Martin Pal, Stephen Wilcox, Lin Tai, Warren S. Alexander, Jane E. Visvader, Stephen L. Nutt, Andreas Strasser, Benjamin Haley, Quan Zhao, Gemma L. Kelly, Marco J. Herold

    Diterbitkan 2022-08-01
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  15. 15
    Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance

    Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance oleh Yexuan Deng, Sarah T. Diepstraten, Margaret A. Potts, Göknur Giner, Stephanie Trezise, Ashley P. Ng, Gerry Healey, Serena R. Kane, Amali Cooray, Kira Behrens, Amy Heidersbach, Andrew J. Kueh, Martin Pal, Stephen Wilcox, Lin Tai, Warren S. Alexander, Jane E. Visvader, Stephen L. Nutt, Andreas Strasser, Benjamin Haley, Quan Zhao, Gemma L. Kelly, Marco J. Herold

    Diterbitkan 2022-08-01
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  16. 16
    Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

    Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex oleh Ganesh Kolumam, Mark Z. Chen, Raymond Tong, Jose Zavala-Solorio, Lance Kates, Nicholas van Bruggen, Jed Ross, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Carano, Diana Ronai Dunshee, Ai-Luen Wu, Benjamin Haley, Keith Anderson, Søren Warming, Xin Y. Rairdan, Nicholas Lewin-Koh, Yingnan Zhang, Johnny Gutierrez, Amos Baruch, Thomas R. Gelzleichter, Dale Stevens, Sharmila Rajan, Travis W. Bainbridge, Jean-Michel Vernes, Y. Gloria Meng, James Ziai, Robert H. Soriano, Matthew J. Brauer, Yongmei Chen, Scott Stawicki, Hok Seon Kim, Laëtitia Comps-Agrar, Elizabeth Luis, Christoph Spiess, Yan Wu, James A. Ernst, Owen P. McGuinness, Andrew S. Peterson, Junichiro Sonoda

    Diterbitkan 2015-07-01
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  17. 17
    Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

    Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer oleh James D Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P Govek, Andiliy G Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric Bischoff, Kyoung-Jin Lee, Celine Bonnefous, Karensa L Douglas, Jackaline D Julien, Johnny Y Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M Giltnane, Ingrid E Wertz, Mark R Lackner, Michelle A Nannini, Deepak Sampath, Luis Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L Arteaga, Richard A Heyman, Peter J Rix, Lori Friedman, Nicholas D Smith, Ciara Metcalfe, Jeffrey H Hager

    Diterbitkan 2019-01-01
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  18. 18
    The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

    The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer oleh James D Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P Govek, Andiliy G Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric Bischoff, Kyoung-Jin Lee, Celine Bonnefous, Karensa L Douglas, Jackaline D Julien, Johnny Y Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M Giltnane, Ingrid E Wertz, Mark R Lackner, Michelle A Nannini, Deepak Sampath, Luis Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L Arteaga, Richard A Heyman, Peter J Rix, Lori Friedman, Nicholas D Smith, Ciara Metcalfe, Jeffrey H Hager

    Diterbitkan 2016-07-01
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