Hasil Pencarian - Bart Vanhaesebroeck

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  1. 1
    Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability

    Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability oleh Bart Vanhaesebroeck, Benoit Bilanges, Ralitsa R. Madsen, Katie L. Dale, Evelyn Lau, Elina Vladimirou

    Diterbitkan 2019-08-01
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  2. 2
    Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice

    Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice oleh Xènia Massana-Muñoz, Marie Goret, Vasugi Nattarayan, David Reiss, Christine Kretz, Gaetan Chicanne, Bernard Payrastre, Bart Vanhaesebroeck, Jocelyn Laporte

    Diterbitkan 2023-08-01
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  3. 3
    Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype.

    Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype. oleh Ralitsa R Madsen, Emily C Erickson, Oscar M Rueda, Xavier Robin, Carlos Caldas, Alex Toker, Robert K Semple, Bart Vanhaesebroeck

    Diterbitkan 2021-11-01
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  4. 4
    Regulation of p110delta PI 3-kinase gene expression.

    Regulation of p110delta PI 3-kinase gene expression. oleh Klaartje Kok, Gemma E Nock, Elizabeth A G Verrall, Michael P Mitchell, Daan W Hommes, Maikel P Peppelenbosch, Bart Vanhaesebroeck

    Diterbitkan 2009-01-01
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  5. 5
    Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype

    Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype oleh Ralitsa R. Madsen, Emily C. Erickson, Oscar M. Rueda, Xavier Robin, Carlos Caldas, Alex Toker, Robert K. Semple, Bart Vanhaesebroeck

    Diterbitkan 2021-11-01
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  6. 6
    PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction

    PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction oleh Brent A. McLean, Vaibhav B. Patel, Pavel Zhabyeyev, Xueyi Chen, Ratnadeep Basu, Faqi Wang, Saumya Shah, Bart Vanhaesebroeck, Gavin Y. Oudit

    Diterbitkan 2019-05-01
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  7. 7
    NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells

    NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells oleh Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei

    Diterbitkan 2023-01-01
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  8. 8
    Leverage of nuclease-deficient CasX for preventing pathological angiogenesis

    Leverage of nuclease-deficient CasX for preventing pathological angiogenesis oleh Haote Han, Yanhui Yang, Yunjuan Jiao, Hui Qi, Zhuo Han, Luping Wang, Lijun Dong, Jingkui Tian, Bart Vanhaesebroeck, Xiaopeng Li, Junwen Liu, Gaoen Ma, Hetian Lei

    Diterbitkan 2023-09-01
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  9. 9
    NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells

    NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells oleh Ralitsa R. Madsen, James Longden, Rachel G. Knox, Xavier Robin, Franziska Völlmy, Kenneth G. Macleod, Larissa S. Moniz, Neil O. Carragher, Rune Linding, Bart Vanhaesebroeck, Robert K. Semple

    Diterbitkan 2021-03-01
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  10. 10
    Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3

    Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3 oleh Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore

    Diterbitkan 2020-07-01
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  11. 11
    Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

    Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity oleh Samira Alliouachene, Benoit Bilanges, Gaëtan Chicanne, Karen E. Anderson, Wayne Pearce, Khaled Ali, Colin Valet, York Posor, Pei Ching Low, Claire Chaussade, Cheryl L. Scudamore, Rachel S. Salamon, Jonathan M. Backer, Len Stephens, Phill T. Hawkins, Bernard Payrastre, Bart Vanhaesebroeck

    Diterbitkan 2015-12-01
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  12. 12
    Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

    Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. oleh Britta J Eickholt, Aminul I Ahmed, Meirion Davies, Evangelia A Papakonstanti, Wayne Pearce, Michelle L Starkey, Antonio Bilancio, Anna C Need, Andrew J H Smith, Susan M Hall, Frank P Hamers, Karl P Giese, Elizabeth J Bradbury, Bart Vanhaesebroeck

    Diterbitkan 2007-09-01
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  13. 13
    Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.

    Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells. oleh Julie Guillermet-Guibert, Lee B Smith, Guillaume Halet, Maria A Whitehead, Wayne Pearce, Diane Rebourcet, Kelly León, Pascale Crépieux, Gemma Nock, Maria Strömstedt, Malin Enerback, Claude Chelala, Mariona Graupera, John Carroll, Sabina Cosulich, Philippa T K Saunders, Ilpo Huhtaniemi, Bart Vanhaesebroeck

    Diterbitkan 2015-07-01
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  14. 14
    A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

    A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease oleh Sarah E. Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Lazaros C. Foukas, Mathias Cobbaut, Sandra D. Castillo, Mohammad Amin Danesh, Mahreen Adil, Arkaitz Carracedo, Mariona Graupera, Neil Q. McDonald, Peter J. Parker, Pedro R. Cutillas, Silvia Surinova, Bart Vanhaesebroeck

    Diterbitkan 2024-08-01
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  15. 15
    PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

    PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease oleh Vaibhav B. Patel, Pavel Zhabyeyev, Xueyi Chen, Faqi Wang, Manish Paul, Dong Fan, Brent A. McLean, Ratnadeep Basu, Pu Zhang, Saumya Shah, John F. Dawson, W. Glen Pyle, Mousumi Hazra, Zamaneh Kassiri, Saugata Hazra, Bart Vanhaesebroeck, Christopher A. McCulloch, Gavin Y. Oudit

    Diterbitkan 2018-12-01
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  16. 16
    1032 Early remodelling of CD4 T cell differentiation in lung squamous carcinogenesis

    1032 Early remodelling of CD4 T cell differentiation in lung squamous carcinogenesis oleh Vítor Teixeira, Kate Davies, Peter Campbell, Bart Vanhaesebroeck, Sam Janes, Kate Gowers, Amalie Kai Bentzen, Teerapon Sahwangarrom, Claudia Peinador Marin, Sam Gamble, Zoe Whiteman, Seng Ung, Lukas Kalinke, Ahmed Alhendi, Adam Pennycuick, Sandra Gomez Lopez, Andrei Enica, Amber Rogers, Kane Foster, Moritz Przybilla, James L Reading

    Diterbitkan 2023-11-01
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  17. 17
    Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

    Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling oleh Inma M. Berenjeno, Roberto Piñeiro, Sandra D. Castillo, Wayne Pearce, Nicholas McGranahan, Sally M. Dewhurst, Valerie Meniel, Nicolai J. Birkbak, Evelyn Lau, Laurent Sansregret, Daniele Morelli, Nnennaya Kanu, Shankar Srinivas, Mariona Graupera, Victoria E. R. Parker, Karen G. Montgomery, Larissa S. Moniz, Cheryl L. Scudamore, Wayne A. Phillips, Robert K. Semple, Alan Clarke, Charles Swanton, Bart Vanhaesebroeck

    Diterbitkan 2017-11-01
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  18. 18
    Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

    Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism oleh Benoit Bilanges, Samira Alliouachene, Wayne Pearce, Daniele Morelli, Gyorgy Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M. Hill, Peter J. Voshol, Lucy Collinson, Christopher Peddie, Khaled Ali, Essam Ghazaly, Vinothini Rajeeve, Georgios Trichas, Shankar Srinivas, Claire Chaussade, Rachel S. Salamon, Jonathan M. Backer, Cheryl L. Scudamore, Maria A. Whitehead, Erin P. Keaney, Leon O. Murphy, Robert K. Semple, Bernard Payrastre, Sharon A. Tooze, Bart Vanhaesebroeck

    Diterbitkan 2017-11-01
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  19. 19
    Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy

    Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy oleh Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund

    Diterbitkan 2021-01-01
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