Hasil Pencarian - Arthur Christopoulos

Perbaiki Hasil
  1. 1
    Structural features embedded in G protein-coupled receptor co-crystal structures are key to their success in virtual screening.

    Structural features embedded in G protein-coupled receptor co-crystal structures are key to their success in virtual screening. oleh Thomas Coudrat, Arthur Christopoulos, Patrick Michael Sexton, Denise Wootten

    Diterbitkan 2017-01-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  2. 2
    Improving virtual screening of G protein-coupled receptors via ligand-directed modeling.

    Improving virtual screening of G protein-coupled receptors via ligand-directed modeling. oleh Thomas Coudrat, John Simms, Arthur Christopoulos, Denise Wootten, Patrick M Sexton

    Diterbitkan 2017-11-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  3. 3
    A simple method to generate stable cell lines for the analysis of transient protein-protein interactions

    A simple method to generate stable cell lines for the analysis of transient protein-protein interactions oleh Emilia Elizabeth Savage, Denise Wootten, Arthur Christopoulos, Patrick Michael Sexton, Sebastian George Barton Furness

    Diterbitkan 2013-04-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  4. 4
    Impact of secretin receptor homo-dimerization on natural ligand binding

    Impact of secretin receptor homo-dimerization on natural ligand binding oleh Kaleeckal G. Harikumar, Sarah J. Piper, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

    Diterbitkan 2024-05-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  5. 5
    Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol

    Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol oleh Kaleeckal G. Harikumar, Thomas Coudrat, Thomas Coudrat, Aditya J. Desai, Maoqing Dong, Daniela G. Dengler, Sebastian G. B. Furness, Arthur Christopoulos, Arthur Christopoulos, Denise Wootten, Denise Wootten, Eduard A. Sergienko, Patrick M. Sexton, Patrick M. Sexton, Laurence J. Miller

    Diterbitkan 2021-12-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  6. 6
    Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

    Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’ oleh Cheng Xue Qin, Lauren T. May, Patrick M. Sexton, Aaron J. DeBono, Jonathan B. Baell, Arthur Christopoulos, Rebecca H. Ritchie

    Diterbitkan 2018-02-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  7. 7
    Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias.

    Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias. oleh Kim Vietz Andreassen, Sara Toftegaard Hjuler, Sebastian G Furness, Patrick M Sexton, Arthur Christopoulos, Olivier Nosjean, Morten Asser Karsdal, Kim Henriksen

    Diterbitkan 2014-01-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  8. 8
    Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias

    Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias oleh Emma T. van der Westhuizen, K. H. Christopher Choy, Celine Valant, Simon McKenzie-Nickson, Sophie J. Bradley, Andrew B. Tobin, Patrick M. Sexton, Arthur Christopoulos

    Diterbitkan 2021-01-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  9. 9
    Cognitive behavioral markers of neurodevelopmental trajectories in rodents

    Cognitive behavioral markers of neurodevelopmental trajectories in rodents oleh K. H. Christopher Choy, Jiaqi K. Luo, Cassandra M. J. Wannan, Liliana Laskaris, Antonia Merritt, Warda T. Syeda, Patrick M. Sexton, Arthur Christopoulos, Christos Pantelis, Jess Nithianantharajah

    Diterbitkan 2021-10-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  10. 10
    Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

    Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure oleh Patricia Rueda, Jon Merlin, Stefano Chimenti, Michel Feletou, Jerome Paysant, Paul J. White, Arthur Christopoulos, Patrick M. Sexton, Roger J. Summers, William N. Charman, Lauren T. May, Christopher J. Langmead

    Diterbitkan 2021-03-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  11. 11
    Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse ColonSummary

    Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse ColonSummary oleh Jesse J. DiCello, Simona E. Carbone, Ayame Saito, Pradeep Rajasekhar, Rhian A. Ceredig, Vi Pham, Celine Valant, Arthur Christopoulos, Nicholas A. Veldhuis, Meritxell Canals, Dominique Massotte, Daniel P. Poole

    Diterbitkan 2020-01-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  12. 12
    Understanding VPAC receptor family peptide binding and selectivity

    Understanding VPAC receptor family peptide binding and selectivity oleh Sarah J. Piper, Giuseppe Deganutti, Jessica Lu, Peishen Zhao, Yi-Lynn Liang, Yao Lu, Madeleine M. Fletcher, Mohammed Akhter Hossain, Arthur Christopoulos, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten

    Diterbitkan 2022-11-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  13. 13
    The role of kinetic context in apparent biased agonism at GPCRs

    The role of kinetic context in apparent biased agonism at GPCRs oleh Carmen Klein Herenbrink, David A. Sykes, Prashant Donthamsetti, Meritxell Canals, Thomas Coudrat, Jeremy Shonberg, Peter J. Scammells, Ben Capuano, Patrick M. Sexton, Steven J. Charlton, Jonathan A. Javitch, Arthur Christopoulos, J. Robert Lane

    Diterbitkan 2016-02-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  14. 14
    Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs

    Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs oleh Scott A. Hollingsworth, Brendan Kelly, Celine Valant, Jordan Arthur Michaelis, Olivia Mastromihalis, Geoff Thompson, A. J. Venkatakrishnan, Samuel Hertig, Peter J. Scammells, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Ron O. Dror

    Diterbitkan 2019-07-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  15. 15
    Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.

    Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity. oleh Jesse I Mobbs, Matthew J Belousoff, Kaleeckal G Harikumar, Sarah J Piper, Xiaomeng Xu, Sebastian G B Furness, Hari Venugopal, Arthur Christopoulos, Radostin Danev, Denise Wootten, David M Thal, Laurence J Miller, Patrick M Sexton

    Diterbitkan 2021-06-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  16. 16
    Defining and unpacking the core concepts of pharmacology education

    Defining and unpacking the core concepts of pharmacology education oleh Marina Santiago, Elizabeth A. Davis, Tina Hinton, Thomas A. Angelo, Alison Shield, Anna‐Marie Babey, Barbara Kemp‐Harper, Gregg Maynard, Hesham S. Al‐Sallami, Ian F. Musgrave, Lynette B. Fernandes, Suong N. T. Ngo, Arthur Christopoulos, Paul J. White

    Diterbitkan 2021-12-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  17. 17
    Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.

    Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling. oleh Kaleeckal G Harikumar, Peishen Zhao, Brian P Cary, Xiaomeng Xu, Aditya J Desai, Maoqing Dong, Jesse I Mobbs, Chirine Toufaily, Sebastian G B Furness, Arthur Christopoulos, Matthew J Belousoff, Denise Wootten, Patrick M Sexton, Laurence J Miller

    Diterbitkan 2024-07-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  18. 18
    Structure and dynamics of the active Gs-coupled human secretin receptor

    Structure and dynamics of the active Gs-coupled human secretin receptor oleh Maoqing Dong, Giuseppe Deganutti, Sarah J. Piper, Yi-Lynn Liang, Maryam Khoshouei, Matthew J. Belousoff, Kaleeckal G. Harikumar, Christopher A. Reynolds, Alisa Glukhova, Sebastian G. B. Furness, Arthur Christopoulos, Radostin Danev, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

    Diterbitkan 2020-08-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  19. 19
    Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants.

    Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants. oleh Patricia Rueda, Elizabeth Harley, Yao Lu, Gregory D Stewart, Stewart Fabb, Natalie Diepenhorst, Béatrice Cremers, Marie-Hélène Rouillon, Isabelle Wehrle, Anne Geant, Gwladys Lamarche, Katie Leach, William N Charman, Arthur Christopoulos, Roger J Summers, Patrick M Sexton, Christopher J Langmead

    Diterbitkan 2016-01-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:
  20. 20
    Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR

    Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR oleh Wessel A. C. Burger, Vi Pham, Ziva Vuckovic, Alexander S. Powers, Jesse I. Mobbs, Yianni Laloudakis, Alisa Glukhova, Denise Wootten, Andrew B. Tobin, Patrick M. Sexton, Steven M. Paul, Christian C. Felder, Radostin Danev, Ron O. Dror, Arthur Christopoulos, Celine Valant, David M. Thal

    Diterbitkan 2023-09-01
    Dapatkan teks lengkap
    Artikel
    Simpan ke Daftar
    Disimpan di:

Alat Pencarian: