Hasil Pencarian - Andrea E. Prota

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  1. 1
    Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.

    Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics. oleh Andrew B Waight, Katja Bargsten, Svetlana Doronina, Michel O Steinmetz, Django Sussman, Andrea E Prota

    Diterbitkan 2016-01-01
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  2. 2
    Computational Approaches to the Rational Design of Tubulin-Targeting Agents

    Computational Approaches to the Rational Design of Tubulin-Targeting Agents oleh Helena Pérez-Peña, Anne-Catherine Abel, Maxim Shevelev, Andrea E. Prota, Stefano Pieraccini, Dragos Horvath

    Diterbitkan 2023-02-01
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  3. 3
    Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure

    Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocryst... oleh Wolfgang Dohle, Andrea E. Prota, Grégory Menchon, Ernest Hamel, Michel O. Steinmetz, Barry V. L. Potter

    Diterbitkan 2019-01-01
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  4. 4
    Abstract OR-8: High-Resolution Structures of Microtubule-Drug Complexes Revealed by Cryo-EM

    Abstract OR-8: High-Resolution Structures of Microtubule-Drug Complexes Revealed by Cryo-EM oleh Kushal Sejwal, Thorsten B. Blum, Joseph Atherton, Ashwani Sharma, Natacha Olieric, Andrea E. Prota, Carolyn A. Moores, Michel O. Steinmetz

    Diterbitkan 2019-06-01
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  5. 5
    Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces

    Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces oleh Xiansha Xiao, Joost Willemse, Patrick Voskamp, Xinmeng Li, Andrea E. Prota, Meindert Lamers, Navraj Pannu, Jan Pieter Abrahams, Gilles P. van Wezel

    Diterbitkan 2021-02-01
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  6. 6
    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin oleh Grégory Menchon, Andrea E. Prota, Daniel Lucena-Agell, Pascal Bucher, Rolf Jansen, Herbert Irschik, Rolf Müller, Ian Paterson, J. Fernando Díaz, Karl-Heinz Altmann, Michel O. Steinmetz

    Diterbitkan 2018-05-01
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  7. 7
    Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells

    Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells oleh Chiara Trigili, Isabel Barasoain, Pedro A. Sánchez-Murcia, Katja Bargsten, Mariano Redondo-Horcajo, Aurora Nogales, Nicola M. Gardner, Arndt Meyer, Guy J. Naylor, Elena Gómez-Rubio, Federico Gago, Michel O. Steinmetz, Ian Paterson, Andrea E. Prota, J. Fernando Díaz

    Diterbitkan 2016-12-01
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  8. 8
    Structural insight into the stabilization of microtubules by taxanes

    Structural insight into the stabilization of microtubules by taxanes oleh Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz

    Diterbitkan 2023-03-01
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  9. 9
    Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

    Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands oleh Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan Francisco Giménez-Abián, April L. Risinger, Erik J. Sorensen, Christopher D. Vanderwal, Karl-Heinz Altmann, Susan L. Mooberry, Michel O. Steinmetz, María Ángela Oliva, Andrea E. Prota, J. Fernando Díaz

    Diterbitkan 2019-03-01
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  10. 10
    Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site

    Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site oleh Christopher J. Smedley, Paul A. Stanley, Mohannad E. Qazzaz, Andrea E. Prota, Natacha Olieric, Hilary Collins, Harry Eastman, Andrew S. Barrow, Kuan-Hon Lim, Toh-Seok Kam, Brian J. Smith, Hendrika M. Duivenvoorden, Belinda S. Parker, Tracey D. Bradshaw, Michel O. Steinmetz, John E. Moses

    Diterbitkan 2018-07-01
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  11. 11
    Structural model for differential cap maturation at growing microtubule ends

    Structural model for differential cap maturation at growing microtubule ends oleh Juan Estévez-Gallego, Fernando Josa-Prado, Siou Ku, Ruben M Buey, Francisco A Balaguer, Andrea E Prota, Daniel Lucena-Agell, Christina Kamma-Lorger, Toshiki Yagi, Hiroyuki Iwamoto, Laurence Duchesne, Isabel Barasoain, Michel O Steinmetz, Denis Chrétien, Shinji Kamimura, J Fernando Díaz, Maria A Oliva

    Diterbitkan 2020-03-01
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  12. 12
    Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

    Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention oleh Thomas Bohnacker, Andrea E. Prota, Florent Beaufils, John E. Burke, Anna Melone, Alison J. Inglis, Denise Rageot, Alexander M. Sele, Vladimir Cmiljanovic, Natasa Cmiljanovic, Katja Bargsten, Amol Aher, Anna Akhmanova, J. Fernando Díaz, Doriano Fabbro, Marketa Zvelebil, Roger L. Williams, Michel O. Steinmetz, Matthias P. Wymann

    Diterbitkan 2017-03-01
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  13. 13
    Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

    Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons oleh Tobias Weinert, Natacha Olieric, Robert Cheng, Steffen Brünle, Daniel James, Dmitry Ozerov, Dardan Gashi, Laura Vera, May Marsh, Kathrin Jaeger, Florian Dworkowski, Ezequiel Panepucci, Shibom Basu, Petr Skopintsev, Andrew S. Doré, Tian Geng, Robert M. Cooke, Mengning Liang, Andrea E. Prota, Valerie Panneels, Przemyslaw Nogly, Ulrich Ermler, Gebhard Schertler, Michael Hennig, Michel O. Steinmetz, Meitian Wang, Jörg Standfuss

    Diterbitkan 2017-09-01
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