Hasil Pencarian - Alison D Axtman

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  1. 1
    Editorial: The next generation of tools and technologies for studying human neurons in a dish

    Editorial: The next generation of tools and technologies for studying human neurons in a dish oleh Thomas M. Durcan, Alison D. Axtman

    Diterbitkan 2023-04-01
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  2. 2
    Exploration of Aberrant E3 Ligases Implicated in Alzheimer’s Disease and Development of Chemical Tools to Modulate Their Function

    Exploration of Aberrant E3 Ligases Implicated in Alzheimer’s Disease and Development of Chemical Tools to Modulate Their Function oleh Frances M. Potjewyd, Alison D. Axtman

    Diterbitkan 2021-11-01
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  3. 3
    PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

    PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor oleh Tigist Y. Tamir, David H. Drewry, Carrow Wells, M. Ben Major, Alison D. Axtman

    Diterbitkan 2020-09-01
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  4. 4
    Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Microglial Model

    Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Microglial Model oleh Swati Mishra, Swati Mishra, Chizuru Kinoshita, Chizuru Kinoshita, Alison D. Axtman, Jessica E. Young, Jessica E. Young

    Diterbitkan 2022-06-01
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  5. 5
    Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity

    Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity oleh Kesatebrhan Haile Asressu, Jeffery L. Smith, Rebekah J. Dickmander, Nathaniel J. Moorman, James Wellnitz, Konstantin I. Popov, Alison D. Axtman, Timothy M. Willson

    Diterbitkan 2024-02-01
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  6. 6
    REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment

    REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment oleh Hao Yang, Daryl Staveness, Steven M. Ryckbosch, Alison D. Axtman, Brian A. Loy, Alexander B. Barnes, Vijay S. Pande, Jacob Schaefer, Paul A. Wender, Lynette Cegelski

    Diterbitkan 2018-01-01
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  7. 7
    Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

    Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis oleh Frances M. Bashore, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran, Alison D. Axtman

    Diterbitkan 2023-04-01
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  8. 8
    Optimization of 3‑Cyano-7-cyclopropylamino-pyrazolo[1,5‑a]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A

    Optimization of 3‑Cyano-7-cyclopropylamino-pyrazolo[1,5‑a]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A oleh Xuan Yang, Han Wee Ong, Rebekah J. Dickmander, Jeffery L. Smith, Jason W. Brown, William Tao, Edcon Chang, Nathaniel J. Moorman, Alison D. Axtman, Timothy M. Willson

    Diterbitkan 2023-10-01
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  9. 9
    Illumination of understudied ciliary kinases

    Illumination of understudied ciliary kinases oleh Raymond G. Flax, Peter Rosston, Peter Rosston, Cecilia Rocha, Brian Anderson, Jacob L. Capener, Thomas M. Durcan, David H. Drewry, David H. Drewry, Panagiotis Prinos, Alison D. Axtman

    Diterbitkan 2024-03-01
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  10. 10
    Open drug discovery in Alzheimer's disease

    Open drug discovery in Alzheimer's disease oleh Alison D. Axtman, Paul E. Brennan, Tristan Frappier‐Brinton, Ranjita Betarbet, Gregory W. Carter, Haian Fu, Opher Gileadi, Anna K. Greenwood, Karina Leal, Frank M. Longo, Lara M. Mangravite, Aled M. Edwards, Allan I. Levey, The Emory‐Sage‐SGC TREAT‐AD Center

    Diterbitkan 2023-04-01
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  11. 11
    Development of SYK NanoBRET cellular target engagement assays for gain–of–function variants

    Development of SYK NanoBRET cellular target engagement assays for gain–of–function variants oleh Jacob L. Capener, James D. Vasta, Vittorio L. Katis, Ani Michaud, Michael T. Beck, Sabrina C. D. Daglish, Sarit Cohen-Kedar, Sarit Cohen-Kedar, Efrat Shaham Barda, Efrat Shaham Barda, Stefanie Howell, Iris Dotan, Iris Dotan, Matthew B. Robers, Alison D. Axtman, Frances M. Bashore

    Diterbitkan 2024-07-01
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  12. 12
    Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

    Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2 oleh Han Wee Ong, Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander, Tammy M. Havener, Marcia K. Sanders, Jason W. Brown, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson

    Diterbitkan 2024-09-01
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  13. 13
    Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

    Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology oleh Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Lang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navlot S Pabla, Alex N Bullock, Tim A Benke, Sila K Ultanir, Alison D Axtman

    Diterbitkan 2023-07-01
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  14. 14
    Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

    Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM oleh Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman

    Diterbitkan 2024-01-01
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  15. 15
    Progress towards a public chemogenomic set for protein kinases and a call for contributions.

    Progress towards a public chemogenomic set for protein kinases and a call for contributions. oleh David H Drewry, Carrow I Wells, David M Andrews, Richard Angell, Hassan Al-Ali, Alison D Axtman, Stephen J Capuzzi, Jonathan M Elkins, Peter Ettmayer, Mathias Frederiksen, Opher Gileadi, Nathanael Gray, Alice Hooper, Stefan Knapp, Stefan Laufer, Ulrich Luecking, Michael Michaelides, Susanne Müller, Eugene Muratov, R Aldrin Denny, Kumar S Saikatendu, Daniel K Treiber, William J Zuercher, Timothy M Willson

    Diterbitkan 2017-01-01
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  16. 16
    Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.

    Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. oleh Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

    Diterbitkan 2024-01-01
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  17. 17
    Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

    Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology oleh Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman

    Diterbitkan 2022-01-01
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  18. 18
    AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

    AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery oleh Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce, Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman

    Diterbitkan 2022-01-01
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  19. 19
    The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

    The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification oleh Carrow I. Wells, Hassan Al-Ali, David M. Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Dikic, Daniel Ebner, Peter Ettmayer, Christian Fischer, Mathias Frederiksen, Robert E. Futrell, Nathanael S. Gray, Stephanie B. Hatch, Stefan Knapp, Ulrich Lücking, Michael Michaelides, Caitlin E. Mills, Susanne Müller, Dafydd Owen, Alfredo Picado, Kumar S. Saikatendu, Martin Schröder, Alexandra Stolz, Mariana Tellechea, Brandon J. Turunen, Santiago Vilar, Jinhua Wang, William J. Zuercher, Timothy M. Willson, David H. Drewry

    Diterbitkan 2021-01-01
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