Hasil Pencarian - Aleksander S. Popel

Perbaiki Hasil
  1. 1
    Protocol for simulating macrophage signal transduction and phenotype polarization using a large-scale mechanistic computational model

    Protocol for simulating macrophage signal transduction and phenotype polarization using a large-scale mechanistic computational model oleh Chen Zhao, Aleksander S. Popel

    Diterbitkan 2021-09-01
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  2. 2
    Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.

    Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells. oleh Hojjat Bazzazi, Aleksander S Popel

    Diterbitkan 2017-02-01
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  3. 3
    Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer.

    Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer. oleh Chen Zhao, Aleksander S Popel

    Diterbitkan 2015-11-01
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  4. 4
    Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.

    Expression of VEGF receptors on endothelial cells in mouse skeletal muscle. oleh Princess I Imoukhuede, Aleksander S Popel

    Diterbitkan 2012-01-01
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  5. 5
    Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches.

    Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches. oleh Feilim Mac Gabhann, Aleksander S Popel

    Diterbitkan 2006-12-01
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  6. 6
    Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.

    Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model. oleh Chen Zhao, Jeffrey S Isenberg, Aleksander S Popel

    Diterbitkan 2017-01-01
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  7. 7
    Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases

    Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases oleh Chen Zhao, Yu Zhang, Aleksander S. Popel

    Diterbitkan 2019-01-01
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  8. 8
    Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

    Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma oleh Haoyang Mi, Won Jin Ho, Won Jin Ho, Mark Yarchoan, Mark Yarchoan, Aleksander S. Popel, Aleksander S. Popel

    Diterbitkan 2022-05-01
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  9. 9
    Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model.

    Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. oleh Prakash Vempati, Feilim Mac Gabhann, Aleksander S Popel

    Diterbitkan 2010-07-01
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  10. 10
    Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

    Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis oleh Kideok Jin, Niranjan B. Pandey, Aleksander S. Popel

    Diterbitkan 2018-06-01
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  11. 11
    Effects of fiber type and size on the heterogeneity of oxygen distribution in exercising skeletal muscle.

    Effects of fiber type and size on the heterogeneity of oxygen distribution in exercising skeletal muscle. oleh Gang Liu, Feilim Mac Gabhann, Aleksander S Popel

    Diterbitkan 2012-01-01
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  12. 12
    Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

    Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager oleh Samira Anbari, Hanwen Wang, Yu Zhang, Jun Wang, Minu Pilvankar, Masoud Nickaeen, Steven Hansel, Aleksander S. Popel, Aleksander S. Popel

    Diterbitkan 2023-06-01
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  13. 13
    Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy.

    Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy. oleh Feilim Mac Gabhann, James W Ji, Aleksander S Popel

    Diterbitkan 2006-09-01
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  14. 14
    Compartment model predicts VEGF secretion and investigates the effects of VEGF Trap in tumor-bearing mice

    Compartment model predicts VEGF secretion and investigates the effects of VEGF Trap in tumor-bearing mice oleh Stacey D Finley, Manjima eDhar, Aleksander S. Popel

    Diterbitkan 2013-07-01
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  15. 15
    Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC

    Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC oleh Hanwen Wang, Theinmozhi Arulraj, Samira Anbari, Aleksander S. Popel

    Diterbitkan 2024-06-01
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  16. 16
    Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation.

    Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation. oleh Wan Hua Tan, Aleksander S Popel, Feilim Mac Gabhann

    Diterbitkan 2013-01-01
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  17. 17
    From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling

    From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling oleh Hanwen Wang, Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel

    Diterbitkan 2024-07-01
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  18. 18
    Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition

    Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition oleh Hanwen Wang, Theinmozhi Arulraj, Holly Kimko, Aleksander S. Popel

    Diterbitkan 2023-06-01
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  19. 19
    Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells

    Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells oleh Min Song, Youli Wang, Brian H. Annex, Aleksander S. Popel

    Diterbitkan 2023-09-01
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  20. 20
    Computational Drug Repositioning for Peripheral Arterial Disease: Prediction of anti-inflammatory and pro-angiogenic therapeutics

    Computational Drug Repositioning for Peripheral Arterial Disease: Prediction of anti-inflammatory and pro-angiogenic therapeutics oleh Liang-Hui eChu, Brian H Annex, Aleksander S. Popel

    Diterbitkan 2015-08-01
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