GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells. by Alboukadel Kassambara, Thierry Rème, Michel Jourdan, Thierry Fest, Dirk Hose, Karin Tarte, Bernard Klein

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Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma. by Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Thierry Rème, Jennifer Torrent, Jean François Rossi, Hartmut Goldschmidt, Bernard Klein

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Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells. by Alboukadel Kassambara, Matthieu Schoenhals, Jérôme Moreaux, Jean-Luc Veyrune, Thierry Rème, Hartmut Goldschmidt, Dirk Hose, Bernard Klein

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Characterization of human FCRL4-positive B cells. by Michel Jourdan, Nicolas Robert, Maïlys Cren, Coraline Thibaut, Christophe Duperray, Alboukadel Kassambara, Michel Cogné, Karin Tarte, Bernard Klein, Jérôme Moreaux

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70 Deciphering the relationship between lymphocytes and macrophages within the tumor micro-environment using a workflow combining RNA transcripts detection and multiplex IHC on Bri... by Jerome Galon, Jacques Fieschi, Aurelie Collignon, Alex Trinh, Marion Olive, Maïté Chamourin, Alboukadel Kassambara, Lucie Sudre, Anthony Lebret, Giovanni Bussoti

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma by Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Brian A. Walker, Alexei Protopopov, Thierry Reme, Franck Pellestor, Véronique Pantesco, Anna Jauch, Gareth Morgan, Hartmut Goldschmidt, Bernard Klein

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PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs by Laurie Herviou, Alboukadel Kassambara, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Carsten Müller-Tidow, Laure Vincent, Anja Seckinger, Hartmut Goldschmidt, Guillaume Cartron, Dirk Hose, Giacomo Cavalli, Jerome Moreaux

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Kinome expression profiling to target new therapeutic avenues in multiple myeloma by Hugues de Boussac, Angélique Bruyer, Michel Jourdan, Anke Maes, Nicolas Robert, Claire Gourzones, Laure Vincent, Anja Seckinger, Guillaume Cartron, Dirk Hose, Elke De Bruyne, Alboukadel Kassambara, Philippe Pasero, Jérôme Moreaux

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The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation by Fabrice Chatonnet, Amandine Pignarre, Aurélien A. Sérandour, Gersende Caron, Stéphane Avner, Nicolas Robert, Alboukadel Kassambara, Audrey Laurent, Maud Bizot, Xabier Agirre, Felipe Prosper, José I. Martin-Subero, Jérôme Moreaux, Thierry Fest, Gilles Salbert

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Dissecting tumor lymphocyte infiltration to predict benefit from immune-checkpoint inhibitors in metastatic colorectal cancer: lessons from the AtezoT RIBE study by Chiara Cremolini, Daniele Rossini, Sara Lonardi, Filippo Pietrantonio, Gianluca Masi, Roberto Moretto, Alessandra Boccaccino, Jerome Galon, Jacques Fieschi, Stefano Tamberi, Gabriella Fontanini, Lisa Salvatore, Clara Ugolini, Alboukadel Kassambara, Emiliano Tamburini, Veronica Conca, Aurélie Catteau, Carlotta Antoniotti, Mirella Giordano, Agnese Proietti, Anello Marcello Poma

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Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung can... by François Ghiringhelli, Frederic Bibeau, Laurent Greillier, Jean-David Fumet, Alis Ilie, Florence Monville, Caroline Laugé, Aurélie Catteau, Isabelle Boquet, Amine Majdi, Erwan Morgand, Youssef Oulkhouir, Nicolas Brandone, Julien Adam, Thomas Sbarrato, Alboukadel Kassambara, Jacques Fieschi, Stéphane Garcia, Anne Laure Lepage, Pascale Tomasini, Jérôme Galon

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460 Spatial distribution of infiltrating T lymphocytes with Immunoscore® CR T cells exhaustion test helps stratification of NSCLC patients treated with PD1/PDL1 inhibitors in the P... by Noémie Resseguier, Julien Mazières, Fabrice Barlesi, Maurice Pérol, Thomas Sbarrato, Fanny Arnoux, Stéphane Garcia, Jacques Fieschi-Meric, Vanina Leca, Alboukadel Kassambara, Lamia Ghezali, Pernelle Outters, Christelle Cotteaux-Lautard, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Luc Odier, Stéphane Hominal, Laurent Greillier

782-C Regulatory T-cell tumor infiltration is associated to better outcome in advanced NSCLC patients under ≥2nd line anti-PD1/L1 monotherapy in the PIONeeR project by Lilian Laborde, Julien Mazières, Fabrice Barlesi, Jacques Fieschi, Maurice Pérol, Vanina Leca, Alboukadel Kassambara, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Stéphane Hominal, Laurent Greillier, Marcellin Landri, Margot Vasseur, Chafik Hamdad, Margaux Mercadal, Laurent Vanhille, Sebastien Benzekry, Stephanie Martinez, Patrice Ray, Lionel Falchero, Antoine Serre, Nicolas Cloarec, Ahmed Frikha, Pierre Bory