Hasil Pencarian - Ajit G. Thomas

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  1. 1
    Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs

    Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs oleh Mariana Figuera-Losada, Ajit G. Thomas, Marigo Stathis, Brent R. Stockwell, Camilo Rojas, Barbara S. Slusher

    Diterbitkan 2017-03-01
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  2. 2
    Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain

    Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain oleh Zhi Zhang, Bassam Bassam, Ajit G. Thomas, Monica Williams, Jinhuan Liu, Elizabeth Nance, Camilo Rojas, Barbara S. Slusher, Sujatha Kannan

    Diterbitkan 2016-10-01
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  3. 3
    High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.

    High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells. oleh Ajit G Thomas, Rita Sattler, Karen Tendyke, Kara A Loiacono, Hans Hansen, Vishal Sahni, Yutaka Hashizume, Camilo Rojas, Barbara S Slusher

    Diterbitkan 2015-01-01
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  4. 4
    GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice

    GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice oleh Yu Su, Meixiang Huang, Ajit G. Thomas, John Maragakis, Kaitlyn D. J. Huizar, Yuxin Zheng, Ying Wu, Mohamed H. Farah, Barbara S. Slusher

    Diterbitkan 2024-06-01
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  5. 5
    D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II

    D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II oleh Sadakatali S. Gori, Ajit G. Thomas, Arindom Pal, Robyn Wiseman, Dana V. Ferraris, Run-duo Gao, Ying Wu, Jesse Alt, Takashi Tsukamoto, Barbara S. Slusher, Rana Rais

    Diterbitkan 2022-09-01
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  6. 6
    T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade

    T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade oleh Kyungho Lee, Elizabeth A. Thompson, Sepideh Gharaie, Chirag H. Patel, Johanna T. Kurzhagen, Phillip M. Pierorazio, Lois J. Arend, Ajit G. Thomas, Sanjeev Noel, Barbara S. Slusher, Hamid Rabb

    Diterbitkan 2023-06-01
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  7. 7
    Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

    Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis oleh Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher, Brent R Stockwell

    Diterbitkan 2014-05-01
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  8. 8
    Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice

    Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice oleh Meixiang Huang, Carolyn Tallon, Xiaolei Zhu, Kaitlyn D. J. Huizar, Silvia Picciolini, Ajit G. Thomas, Lukas Tenora, Wathsala Liyanage, Francesca Rodà, Alice Gualerzi, Rangaramanujam M. Kannan, Marzia Bedoni, Rana Rais, Barbara S. Slusher

    Diterbitkan 2023-09-01
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  9. 9
    Preventing Allograft Rejection by Targeting Immune Metabolism

    Preventing Allograft Rejection by Targeting Immune Metabolism oleh Chen-Fang Lee, Ying-Chun Lo, Chih-Hsien Cheng, Georg J. Furtmüller, Byoungchol Oh, Vinicius Andrade-Oliveira, Ajit G. Thomas, Caitlyn E. Bowman, Barbara S. Slusher, Michael J. Wolfgang, Gerald Brandacher, Jonathan D. Powell

    Diterbitkan 2015-10-01
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  10. 10
    Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV

    Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV oleh Xiaolei Zhu, Kristen R. Hollinger, Yiyao Huang, Alejandra Borjabad, Boe-Hyun Kim, Tanina Arab, Ajit G. Thomas, Mohammed Moniruzzaman, Lyndah Lovell, Andrey Turchinovich, Kenneth W. Witwer, David J. Volsky, Norman J. Haughey, Barbara S. Slusher

    Diterbitkan 2022-07-01
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  11. 11
    Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.

    Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. oleh Mariana Figuera-Losada, Marigo Stathis, Joelle M Dorskind, Ajit G Thomas, Veera Venkata Ratnam Bandaru, Seung-Wan Yoo, Nicholas J Westwood, Graeme W Rogers, Justin C McArthur, Norman J Haughey, Barbara S Slusher, Camilo Rojas

    Diterbitkan 2015-01-01
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  12. 12
    Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice

    Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice oleh Carolyn Tallon, Benjamin J. Bell, Anjali Sharma, Arindom Pal, Medhinee M. Malvankar, Ajit G. Thomas, Seung-Wan Yoo, Kristen R. Hollinger, Kaleem Coleman, Elizabeth L. Wilkinson, Sujatha Kannan, Norman J. Haughey, Rangaramanujam M. Kannan, Rana Rais, Barbara S. Slusher

    Diterbitkan 2022-09-01
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  13. 13
    Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model

    Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model oleh Carolyn Tallon, Benjamin J. Bell, Medhinee M. Malvankar, Pragney Deme, Carlos Nogueras-Ortiz, Erden Eren, Ajit G. Thomas, Kristen R. Hollinger, Arindom Pal, Maja Mustapic, Meixiang Huang, Kaleem Coleman, Tawnjerae R. Joe, Rana Rais, Norman J. Haughey, Dimitrios Kapogiannis, Barbara S. Slusher

    Diterbitkan 2023-12-01
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