Site-specific characterization of endogenous SUMOylation across species and organs

oleh: Ivo A. Hendriks, David Lyon, Dan Su, Niels H. Skotte, Jeremy A. Daniel, Lars J. Jensen, Michael L. Nielsen

Format: Article
Diterbitkan: Nature Portfolio 2018-06-01

Deskripsi

Proteomics is a powerful method to study protein SUMOylation, but system-wide insights into endogenous SUMO2/3 modification events are still sparse. Here, the authors develop a more sensitive SUMO proteomics approach, providing detailed maps of endogenous SUMO2/3 sites in human cells and mouse tissues.