Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia
oleh: Hao Chung The, Ladaporn Bodhidatta, Duy Thanh Pham, Carl J. Mason, Tuyen Ha Thanh, Phat Voong Vinh, Paul Turner, Sopheak Hem, David A. B. Dance, Paul N. Newton, Rattanaphone Phetsouvanh, Viengmon Davong, Guy E. Thwaites, Nicholas R. Thomson, Stephen Baker, Maia A. Rabaa
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Hao Chung The et al. analyze 1,804 Shigella genome sequences from organisms isolated in four Southeast Asian countries over three decades to study the evolution of both S. flexneri and S. sonnei. This study suggests that adaptation to antimicrobial pressure may have played a pivotal role in the recent evolutionary trajectory of Shigella in Southeast Asia.