Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient

oleh: Rachel M. Wheatley, Julio Diaz Caballero, Thomas E. van der Schalk, Fien H. R. De Winter, Liam P. Shaw, Natalia Kapel, Claudia Recanatini, Leen Timbermont, Jan Kluytmans, Mark Esser, Alicia Lacoma, Cristina Prat-Aymerich, Antonio Oliver, Samir Kumar-Singh, Surbhi Malhotra-Kumar, R. Craig MacLean

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

In this paper the authors show that the pathogenic bacterium Pseudomonas aeruginosa migrates between the gut and lungs of an ICU patient, and that differential evolutionary responses to antibiotic treatment occur in these organs.