Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing. Por Wilbert P Vermeij, Claude Backendorf

Obter o texto integral

Comparison of two bioelectrical impedance analyzers for estimating body composition in a cohort of pediatric oncology patients Por Denise Froon-Torenstra, Lisanne Renting, Dieuwertje E. Kok, Wilbert P. Vermeij, Wim J.E. Tissing

Obter o texto integral

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration Por Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma

Obter o texto integral

Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health Por María Björk Birkisdóttir, María Björk Birkisdóttir, María Björk Birkisdóttir, Lisanne J. Van’t Sant, Renata M. C. Brandt, Sander Barnhoorn, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Wilbert P. Vermeij, Dick Jaarsma

Obter o texto integral

Gene expression changes in cerebellum induced by dietary restriction Por Lisanne J. van’t Sant, María B. Birkisdóttir, María B. Birkisdóttir, María B. Birkisdóttir, Rutger A. Ozinga, Rutger A. Ozinga, Ákos Gyenis, Jan H.J. Hoeijmakers, Jan H.J. Hoeijmakers, Jan H.J. Hoeijmakers, Jan H.J. Hoeijmakers, Wilbert P. Vermeij, Wilbert P. Vermeij, Dick Jaarsma

Obter o texto integral

Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice Por Sander Barnhoorn, Marcel E Meima, Robin P Peeters, Veerle M Darras, Selmar Leeuwenburgh, Jan H J Hoeijmakers, Wilbert P Vermeij, W Edward Visser

Obter o texto integral

A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia Por Yupeng He, Marlien van Mever, Wei Yang, Luojiao Huang, Rawi Ramautar, Yvonne Rijksen, Wilbert P. Vermeij, Jan H. J. Hoeijmakers, Amy C. Harms, Peter W. Lindenburg, Thomas Hankemeier

Obter o texto integral

Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice Por Dick Jaarsma, Maria B. Birkisdóttir, Randy van Vossen, Demi W.G.D. Oomen, Oussama Akhiyat, Wilbert P. Vermeij, Sebastiaan K.E. Koekkoek, Chris I. De Zeeuw, Laurens W.J. Bosman

Obter o texto integral

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 −/Δ7 mice Por Benthe van der Lugt, Adriaan A. van Beek, Steven Aalvink, Ben Meijer, Bruno Sovran, Wilbert P. Vermeij, Renata M. C. Brandt, Willem M. de Vos, Huub F. J. Savelkoul, Wilma T. Steegenga, Clara Belzer

Obter o texto integral

Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity Por Christiaan A. J. Oudmaijer, Christiaan A. J. Oudmaijer, Winnie M. C. van den Boogaard, Winnie M. C. van den Boogaard, Daphne S. J. Komninos, Daphne S. J. Komninos, Emma J. Verwaaijen, Hanneke M. van Santen, Hanneke M. van Santen, Marc R. Lilien, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Marc H. W. Wijnen, Marry M. van den Heuvel-Eibrink, Wilbert P. Vermeij, Wilbert P. Vermeij

Obter o texto integral

Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside Por María B. Birkisdóttir, María B. Birkisdóttir, Ivar van Galen, Ivar van Galen, Renata M. C. Brandt, Sander Barnhoorn, Nicole van Vliet, Claire van Dijk, Claire van Dijk, Bhawani Nagarajah, Sandra Imholz, Conny T. van Oostrom, Erwin Reiling, Ákos Gyenis, Pier G. Mastroberardino, Pier G. Mastroberardino, Pier G. Mastroberardino, Dick Jaarsma, Harry van Steeg, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Martijn E. T. Dollé, Wilbert P. Vermeij, Wilbert P. Vermeij

Obter o texto integral

The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside Por María B. Birkisdóttir, María B. Birkisdóttir, Ivar van Galen, Ivar van Galen, Renata M. C. Brandt, Sander Barnhoorn, Nicole van Vliet, Claire van Dijk, Claire van Dijk, Bhawani Nagarajah, Sandra Imholz, Conny T. van Oostrom, Erwin Reiling, Ákos Gyenis, Pier G. Mastroberardino, Pier G. Mastroberardino, Pier G. Mastroberardino, Dick Jaarsma, Harry van Steeg, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Jan H. J. Hoeijmakers, Martijn E. T. Dollé, Wilbert P. Vermeij, Wilbert P. Vermeij

Obter o texto integral

Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice Por Yupeng He, Wei Yang, Luojiao Huang, Marlien Admiraal‐van Mever, Rawi Ramautar, Amy Harms, Yvonne Rijksen, Renata M.C. Brandt, Sander Barnhoorn, Kimberly Smit, Dick Jaarsma, Peter Lindenburg, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Thomas Hankemeier

Obter o texto integral

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency. Por Sander Barnhoorn, Lieneke M Uittenboogaard, Dick Jaarsma, Wilbert P Vermeij, Maria Tresini, Michael Weymaere, Hervé Menoni, Renata M C Brandt, Monique C de Waard, Sander M Botter, Altaf H Sarker, Nicolaas G J Jaspers, Gijsbertus T J van der Horst, Priscilla K Cooper, Jan H J Hoeijmakers, Ingrid van der Pluijm

Obter o texto integral

Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling Por Khalid Alyodawi, Wilbert P. Vermeij, Saleh Omairi, Oliver Kretz, Mark Hopkinson, Francesca Solagna, Barbara Joch, Renata M.C. Brandt, Sander Barnhoorn, Nicole vanVliet, Yanto Ridwan, Jeroen Essers, Robert Mitchell, Taryn Morash, Arja Pasternack, Olli Ritvos, Antonios Matsakas, Henry Collins‐Hooper, Tobias B. Huber, Jan H.J. Hoeijmakers, Ketan Patel

Obter o texto integral

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering Por Chiara Milanese, Cíntia R. Bombardieri, Sara Sepe, Sander Barnhoorn, César Payán-Goméz, Donatella Caruso, Matteo Audano, Silvia Pedretti, Wilbert P. Vermeij, Renata M. C. Brandt, Akos Gyenis, Mirjam M. Wamelink, Annelieke S. de Wit, Roel C. Janssens, René Leen, André B. P. van Kuilenburg, Nico Mitro, Jan H. J. Hoeijmakers, Pier G. Mastroberardino

Obter o texto integral

Cellular senescence drives age-dependent hepatic steatosis Por Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L. Wilson, Albert Lahat, Christoper P. Day, Alastair Burt, Allyson Palmer, Quentin M. Anstee, Sushma Nagaraja Grellscheid, Jan H J. Hoeijmakers, Sander Barnhoorn, Derek A. Mann, Thomas G. Bird, Wilbert P. Vermeij, James L. Kirkland, João F. Passos, Thomas von Zglinicki, Diana Jurk

Obter o texto integral

Supplementation with Lactobacillus plantarum WCFS1 prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1-/Δ7 Mice Por Adriaan A Van Beek, Adriaan A Van Beek, Adriaan A Van Beek, Bruno Sovran, Bruno Sovran, Floor Hugenholtz, Floor Hugenholtz, Ben Meijer, Joanne Hoogerland, Violeta Mihailova, Corine van der Ploeg, Clara Belzer, Clara Belzer, Mark V Boekschoten, Mark V Boekschoten, Jan JH Hoeijmakers, Wilbert P Vermeij, Paul De Vos, Jerry M Wells, Jerry M Wells, Pieter JM Leenen, Claudio Nicoletti, Claudio Nicoletti, Rudi W Hendriks, Huub FJ Savelkoul, Huub FJ Savelkoul

Obter o texto integral

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging. Por W Edward Visser, Cíntia R Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A Garinis, Robin P Peeters, Marco Medici, Willy van Ham, Wilbert P Vermeij, Monique C de Waard, Ronald R de Krijger, Anita Boelen, Joan Kwakkel, John J Kopchick, Edward O List, Joost P M Melis, Veerle M Darras, Martijn E T Dollé, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Theo J Visser

Obter o texto integral