Editorial for Special Issue “Advances in the Pathogenesis and Treatment of Immune-Mediated Inflammatory Diseases” od Jan Piet van Hamburg, Sander W. Tas

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The Role of Endothelial Cells and TNF-Receptor Superfamily Members in Lymphoid Organogenesis and Function During Health and Inflammation od Kim C. M. Jeucken, Kim C. M. Jeucken, Jasper J. Koning, Reina E. Mebius, Sander W. Tas, Sander W. Tas

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Editorial: Non-canonical NF-κB signaling in immune-mediated inflammatory diseases and malignancies od Sander W. Tas, Sander W. Tas, Vanessa L. Bryant, Vanessa L. Bryant, Vanessa L. Bryant, Matthew C. Cook, Matthew C. Cook

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B Lineage Cells in ANCA-Associated Vasculitis od Ana Merino-Vico, Jan Piet van Hamburg, Sander W. Tas

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Various Tastes of Sugar: The Potential of Glycosylation in Targeting and Modulating Human Immunity via C-Type Lectin Receptors od Stefanie Busold, Noémi A. Nagy, Sander W. Tas, Sander W. Tas, Ronald van Ree, Ronald van Ree, Esther C. de Jong, Teunis B. H. Geijtenbeek

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A Straightforward Method for 3D Visualization of B Cell Clusters and High Endothelial Venules in Lymph Nodes Highlights Differential Roles of TNFRI and -II od Kim C. M. Jeucken, Kim C. M. Jeucken, Jasper J. Koning, Jan Piet van Hamburg, Jan Piet van Hamburg, Reina E. Mebius, Sander W. Tas, Sander W. Tas

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Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance od Noémi Anna Nagy, Aram M. de Haas, Teunis B. H. Geijtenbeek, Ronald van Ree, Ronald van Ree, Sander W. Tas, Sander W. Tas, Yvette van Kooyk, Esther C. de Jong

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Symptomatic creatine phosphokinase elevation in a Crohn's disease patient caused by upadacitinib od Anna Schuitema, Suzanne I. Anjie, Agnies M. vanEeghen, Sander W. Tas, Mark Löwenberg

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Toll-like receptor 4 and Syk kinase shape dendritic cell-induced immune activation to major house dust mite allergens od Stefanie Busold, Stefanie Busold, Jaap H. Akkerdaas, Jaap H. Akkerdaas, Esther M. Zijlstra-Willems, Esther M. Zijlstra-Willems, Kees van der Graaf, Sander W. Tas, Sander W. Tas, Sander W. Tas, Esther C. de Jong, Esther C. de Jong, Ronald van Ree, Ronald van Ree, Ronald van Ree, Teunis B. H. Geijtenbeek, Teunis B. H. Geijtenbeek

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In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones od Anne Musters, Giulia Balzaretti, Giulia Balzaretti, Barbera D. C. van Schaik, Aldo Jongejan, Linda van der Weele, Linda van der Weele, Sander W. Tas, Sander W. Tas, Antoine H. C. van Kampen, Niek de Vries, Niek de Vries

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A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages od Eva M. L. Philippon, Eva M. L. Philippon, Lisanne J. E. van Rooijen, Lisanne J. E. van Rooijen, Fatemeh Khodadust, Jan Piet van Hamburg, Jan Piet van Hamburg, Conny J. van der Laken, Sander W. Tas, Sander W. Tas

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Liposomes loaded with vitamin D3 induce regulatory circuits in human dendritic cells od Noémi Anna Nagy, Fernando Lozano Vigario, Rinske Sparrius, Toni M. M. van Capel, Ronald van Ree, Ronald van Ree, Sander W. Tas, Sander W. Tas, I. Jolanda M. de Vries, Teunis B. H. Geijtenbeek, Bram Slütter, Esther C. de Jong, for the DC4Balance consortium

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Discovery of innovative therapies for rare immune-mediated inflammatory diseases via off-label prescription of biologics: the case of IL-6 receptor blockade in Castleman’s disease... od Anne eMusters, Amira M.N. Assaf, Danielle M. Gerlag, Paul P. Tak, Paul P. Tak, Paul P. Tak, Sander W. Tas

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Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis od Fatemeh Khodadust, Aiarpi Ezdoglian, Maarten M. Steinz, Judy R. van Beijnum, Gerben J. C. Zwezerijnen, Gerrit Jansen, Sander W. Tas, Conny J. van der Laken

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Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens od Joannah R. Fergusson, Michael D. Morgan, Melanie Bruchard, Leonie Huitema, Leonie Huitema, Balthasar A. Heesters, Vincent van Unen, Jan Piet van Hamburg, Jan Piet van Hamburg, Nicole N. van der Wel, Daisy Picavet, Frits Koning, Sander W. Tas, Sander W. Tas, Mark S. Anderson, John C. Marioni, John C. Marioni, John C. Marioni, Georg A. Holländer, Hergen Spits

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IL-12p40/IL-23p40 Blockade With Ustekinumab Decreases the Synovial Inflammatory Infiltrate Through Modulation of Multiple Signaling Pathways Including MAPK-ERK and Wnt od Renée H. Fiechter, Renée H. Fiechter, Renée H. Fiechter, Henriëtte M. de Jong, Henriëtte M. de Jong, Henriëtte M. de Jong, Leonieke J. J. van Mens, Leonieke J. J. van Mens, Leonieke J. J. van Mens, Inka A. Fluri, Inka A. Fluri, Inka A. Fluri, Sander W. Tas, Sander W. Tas, Sander W. Tas, Dominique L. P. Baeten, Dominique L. P. Baeten, Dominique L. P. Baeten, Nataliya G. Yeremenko, Nataliya G. Yeremenko, Nataliya G. Yeremenko, Marleen G. H. van de Sande, Marleen G. H. van de Sande, Marleen G. H. van de Sande

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Efficient Neutrophil Activation Requires Two Simultaneous Activating Stimuli od Sanne Mol, Florianne M. J. Hafkamp, Laura Varela, Neena Simkhada, Esther W. Taanman-Kueter, Sander W. Tas, Marca H. M. Wauben, Tom Groot Kormelink, Esther C. de Jong

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Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression od Kim C. M. Jeucken, Merlijn H. Kaaij, Jasper Rip, Charlotte C. N. van Rooijen, Yik Y. Kan, Odilia B. J. Corneth, Jan Piet van Hamburg, Sander W. Tas

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Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells od Kim C. M. Jeucken, Kim C. M. Jeucken, Charlotte C. N. van Rooijen, Charlotte C. N. van Rooijen, Yik Y. Kan, Yik Y. Kan, Lotte A. Kocken, Lotte A. Kocken, Aldo Jongejan, Abraham C. I. van Steen, Jaap D. van Buul, Jaap D. van Buul, Henric K. Olsson, Jan Piet van Hamburg, Jan Piet van Hamburg, Sander W. Tas, Sander W. Tas

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Ultrasound-guided lymph node biopsy sampling to study the immunopathogenesis of rheumatoid arthritis: a well-tolerated valuable research tool od Renée H. Fiechter, Janne W. Bolt, Marleen G. H. van de Sande, Caroline J. Aalbers, Robert B. M. Landewé, Mario Maas, Sander W. Tas, Lisa G. M. van Baarsen

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