Indicators of intensive care unit capacity strain: a systematic review by Oleksa G. Rewa, Henry T. Stelfox, Armann Ingolfsson, David A. Zygun, Robin Featherstone, Dawn Opgenorth, Sean M. Bagshaw

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Continuous renal replacement therapy and transplant-free survival in acute liver failure: protocol for a systematic review and meta-analysis by Andrea M. Robinson, C. J. Karvellas, Joanna C. Dionne, Robin Featherstone, Meghan Sebastianski, Ben Vandermeer, Oleksa G. Rewa

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Determining the optimal time for liberation from renal replacement therapy in critically ill patients: a systematic review and meta-analysis (DOnE RRT) by Riley Jeremy Katulka, Abdalrhman Al Saadon, Meghan Sebastianski, Robin Featherstone, Ben Vandermeer, Samuel A. Silver, R. T. Noel Gibney, Sean M. Bagshaw, Oleksa G. Rewa

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Coronavirus disease 2019 (COVID-19) excess mortality outcomes associated with pandemic effects study (COPES): A systematic review and meta-analysis by David Lu, Sumeet Dhanoa, Harleen Cheema, Kimberley Lewis, Kimberley Lewis, Patrick Geeraert, Benjamin Merrick, Aaron Vander Leek, Meghan Sebastianski, Brittany Kula, Dipayan Chaudhuri, John Basmaji, Arnav Agrawal, Arnav Agrawal, Dan Niven, Kirsten Fiest, Henry T. Stelfox, Danny J. Zuege, Oleksa G. Rewa, Oleksa G. Rewa, Sean M. Bagshaw, Sean M. Bagshaw, Vincent I. Lau

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LIBERATE: a study protocol for midodrine for the early liberation from vasopressor support in the intensive care unit (LIBERATE): protocol for a randomized controlled trial by Dawn Opgenorth, Nadia Baig, Kirsten Fiest, Constantine Karvellas, Jim Kutsogiannis, Vincent Lau, Erika Macintyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Xiaoming Wang, Sean M. Bagshaw, Oleksa G. Rewa

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A study protocol for improving the delivery of acute kidney replacement therapy (KRT) to critically ill patients in Alberta – DIALYZING WISELY by Dawn Opgenorth, Sean M. Bagshaw, Vincent Lau, Michelle M. Graham, Nancy Fraser, Scott Klarenbach, Louise Morrin, Colleen Norris, Neesh Pannu, Selvi Sinnadurai, Shelley Valaire, Xiaoming Wang, Oleksa G. Rewa

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Plasma essential fatty acid on hospital admission is a marker of COVID-19 disease severity by Vera C. Mazurak, Irma Magaly Rivas-Serna, Sarah R. Parsons, Md Monirujjaman, Krista E. Maybank, Stanley K. Woo, Oleksa G. Rewa, Andrew J. Cave, Caroline Richard, M. Thomas Clandinin

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Epidemiology and Outcomes of AKI Treated With Continuous Kidney Replacement Therapy: The Multicenter CRRTnet StudyPlain Language Summary by Oleksa G. Rewa, Victor Ortiz-Soriano, Joshua Lambert, Shaowli Kabir, Michael Heung, Andrew A. House, Divya Monga, Luis A. Juncos, Michelle Secic, Robin Piazza, Stuart L. Goldstein, Sean M. Bagshaw, Javier A. Neyra

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Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis by Oleksa G Rewa, Sean M Bagshaw, Bram Rochwerg, Janek Senaratne, Xiaoming Wang, Kirsten Fiest, Jim Kutsogiannis, Wendy Sligl, Dawn Opgenorth, Vincent Lau, Mostafa Kamaleldin, Sebastian Kilcommons, Constantine Jason Karvellas, Erika MacIntyre, Jocelyn Slemko

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Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for... by Jean Deschamps, James Gilbertson, Sebastian Straube, Kathryn Dong, Frank P. MacMaster, Christina Korownyk, Lori Montgomery, Ryan Mahaffey, James Downar, Hance Clarke, John Muscedere, Katherine Rittenbach, Robin Featherstone, Meghan Sebastianski, Ben Vandermeer, Deborah Lynam, Ryan Magnussen, Sean M. Bagshaw, Oleksa G. Rewa

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Non-COVID outcomes associated with the coronavirus disease-2019 (COVID-19) pandemic effects study (COPES): A systematic review and meta-analysis. by Vincent Issac Lau, Sumeet Dhanoa, Harleen Cheema, Kimberley Lewis, Patrick Geeraert, David Lu, Benjamin Merrick, Aaron Vander Leek, Meghan Sebastianski, Brittany Kula, Dipayan Chaudhuri, Arnav Agarwal, Daniel J Niven, Kirsten M Fiest, Henry T Stelfox, Danny J Zuege, Oleksa G Rewa, Sean M Bagshaw

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Association between supportive interventions and healthcare utilization and outcomes in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a s... by Jean Deschamps, James Gilbertson, Sebastian Straube, Kathryn Dong, Frank P. MacMaster, Christina Korownyk, Lori Montgomery, Ryan Mahaffey, James Downar, Hance Clarke, John Muscedere, Katherine Rittenbach, Robin Featherstone, Meghan Sebastianski, Ben Vandermeer, Deborah Lynam, Ryan Magnussen, Sean M. Bagshaw, Oleksa G. Rewa

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Acute Respiratory Distress Syndrome and Shunt Detection With Bubble Studies: A Systematic Review and Meta-Analysis by Jeffrey Odenbach, MD, FRCPC, Sumeet Dhanoa, BSc, Meghan Sebastianski, BSc, MPH, PhD, Lazar Milovanovic, MD, FRCPC, Andrea Robinson, MD, FRCPC, Graham Mah, MD, FRCPC, Oleksa G. Rewa, MD, MSc, FRCPC, Sean M. Bagshaw, MD, MSc, FRCPC, Brian Buchanan, MD, MMed, FRCPC, Vincent I. Lau, MD, MSc, FRCPC

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Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors in COVID-19: Meta-analysis/Meta-regression Adjusted for Confounding Factors by Terry Lee, PhD, Alessandro Cau, BSc, Matthew Pellan Cheng, MD, Adeera Levin, MD, Todd C. Lee, MD, Donald C. Vinh, MD, Francois Lamontagne, MD, Joel Singer, PhD, Keith R. Walley, MD, Srinivas Murthy, MD, David Patrick, MD, Oleksa G. Rewa, MD, Brent W. Winston, MD, John Marshall, MD, John Boyd, MD, Karen Tran, MD, Andre C. Kalil, MD, Russell Mcculoh, MD, Robert Fowler, MD, James M. Luther, MD, James A. Russell, MD

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Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review by Stephana J. Moss, Karla D. Krewulak, Henry T. Stelfox, Sofia B. Ahmed, Melanie C. Anglin, Sean M. Bagshaw, Karen E. A. Burns, Deborah J. Cook, Christopher J. Doig, Alison Fox-Robichaud, Robert Fowler, Laura Hernández, Michelle E. Kho, Maia Kredentser, Kira Makuk, Srinivas Murthy, Daniel J. Niven, Kendiss Olafson, Ken Kuljit S. Parhar, Scott B. Patten, Oleksa G. Rewa, Bram Rochwerg, Bonnie Sept, Andrea Soo, Krista Spence, Sean Spence, Sharon Straus, Andrew West, Jeanna Parsons Leigh, Kirsten M. Fiest

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Systemic Nonsteroidal Anti-Inflammatories for Analgesia in Postoperative Critical Care Patients: A Systematic Review and Meta-Analysis of Randomized Control Trials by Chen Hsiang Ma, MD, Kimberly B. Tworek, BScN, Janice Y. Kung, MLIS, Sebastian Kilcommons, BSc, Kathleen Wheeler, MD, Arabesque Parker, MD, MSc, Janek Senaratne, MD, MSc, Erika Macintyre, MD, Wendy Sligl, MD, MSc, Constantine J. Karvellas, MD, MSc, Fernando G. Zampieri, MD, PhD, Demetrios Jim Kutsogiannis, MD, MSc, John Basmaji, MD, Kimberley Lewis, MD, MSc, Dipayan Chaudhuri, MD, MSc, Sameer Sharif, MD, Oleksa G. Rewa, MD, MSc, Bram Rochwerg, MD, MSc, Sean M. Bagshaw, MD, MSc, Vincent I. Lau, MD, MSc

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Lessening Organ Dysfunction With Vitamin C (LOVIT) Trial: Statistical Analysis Plan by Neill KJ Adhikari, Ruxandra Pinto, Andrew G Day, Marie-Hélène Masse, Julie Ménard, Sheila Sprague, Djillali Annane, Yaseen M Arabi, Marie-Claude Battista, Dian Cohen, Deborah J Cook, Gordon H Guyatt, Daren K Heyland, Salmaan Kanji, Shay P McGuinness, Rachael L Parke, Bharath Kumar Tirupakuzhi Vijayaraghavan, Emmanuel Charbonney, Michaël Chassé, Lorenzo Del Sorbo, Demetrios James Kutsogiannis, François Lauzier, Rémi Leblanc, David M Maslove, Sangeeta Mehta, Armand Mekontso Dessap, Tina S Mele, Bram Rochwerg, Oleksa G Rewa, Jason Shahin, Pawel Twardowski, Paul Jeffrey Young, François Lamontagne

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A Modified Delphi Process to Prioritize Experiences and Guidance Related to ICU Restricted Visitation Policies During the Coronavirus Disease 2019 Pandemic by Kirsten M. Fiest, PhD, Karla D. Krewulak, PhD, Kira Makuk, BHSc, Natalia Jaworska, MD, MSc, Laura Hernández, BA, Sean M. Bagshaw, MD, MSc, Karen E. Burns, MD, MSc, Deborah J. Cook, MD, MSc, Christopher J. Doig, MD, MSc, Alison Fox-Robichaud, MD, MSc, Robert A. Fowler, MD, MSc, Michelle E. Kho, PT, PhD, Ken Kuljit S. Parhar, MD, MSc, Oleksa G. Rewa, MD, MSc, Bram Rochwerg, MD, MSc, Bonnie G. Sept, Andrea Soo, PhD, Sean Spence, MD, Andrew West, EdD, Henry T. Stelfox, MD, PhD, Jeanna Parsons Leigh, PhD, for the Canadian Critical Care Trials Group, Kusum Menon, Vazquez Grande, Mark Duffet, Jennifer Foster, Dominique Piquette, Nicole Zytaruk, Sylvie Debigaré, Srinivas Murthy, Danaë Tassy, Sangeeta Mehta

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