The Innate Immune Playbook for Restricting West Nile Virus Infection حسب Kendra M. Quicke, Mehul S. Suthar

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Innate immune sensing of flaviviruses. حسب Mehul S Suthar, Sebastian Aguirre, Ana Fernandez-Sesma

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Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7. حسب Stephane Daffis, Mehul S Suthar, Kristy J Szretter, Michael Gale, Michael S Diamond

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Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling. حسب Elizabeth J Faul, Celestine N Wanjalla, Mehul S Suthar, Michael Gale, Christoph Wirblich, Matthias J Schnell

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Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo حسب Troy von Beck, Luis Mena Hernandez, Hongyi Zhou, Katharine Floyd, Mehul S. Suthar, Jeffrey Skolnick, Joshy Jacob

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Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection. حسب James D Brien, Stephane Daffis, Helen M Lazear, Hyelim Cho, Mehul S Suthar, Michael Gale, Michael S Diamond

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Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses. حسب Kelsey Roe, Daniela Giordano, Lucy B Young, Kevin E Draves, Ursula Holder, Mehul S Suthar, Michael Gale, Edward A Clark

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Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission. حسب Ketaki Ganti, Lucas M Ferreri, Chung-Young Lee, Camden R Bair, Gabrielle K Delima, Kate E Holmes, Mehul S Suthar, Anice C Lowen

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Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability حسب Daniel M. Chopyk, Johnasha D. Stuart, Matthew G. Zimmerman, Jing Wen, Sanjeev Gumber, Mehul S. Suthar, Manoj Thapa, Mark J. Czaja, Arash Grakoui

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Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient حسب Siddhartha K. Bhaumik, Lalita Priyamvada, Robert C. Kauffman, Lilin Lai, Muktha S. Natrajan, Alice Cho, Nadine Rouphael, Mehul S. Suthar, Mark J. Mulligan, Jens Wrammert

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A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes. حسب Mehul S Suthar, Margaret M Brassil, Gabriele Blahnik, Aimee McMillan, Hilario J Ramos, Sean C Proll, Sarah E Belisle, Michael G Katze, Michael Gale

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Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection. حسب Stacey A Lapp, Venkata Viswanadh Edara, Austin Lu, Lilin Lai, Laila Hussaini, Ann Chahroudi, Larry J Anderson, Mehul S Suthar, Evan J Anderson, Christina A Rostad

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Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes حسب Jessica B. Graham, Sunil Thomas, Jessica Swarts, Aimee A. McMillan, Martin T. Ferris, Mehul S. Suthar, Piper M. Treuting, Renee Ireton, Michael Gale, Jennifer M. Lund

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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation حسب Nicholas K. Hurlburt, Emilie Seydoux, Yu-Hsin Wan, Venkata Viswanadh Edara, Andrew B. Stuart, Junli Feng, Mehul S. Suthar, Andrew T. McGuire, Leonidas Stamatatos, Marie Pancera

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Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells. حسب James R Bowen, Kendra M Quicke, Mohan S Maddur, Justin T O'Neal, Circe E McDonald, Nadia B Fedorova, Vinita Puri, Reed S Shabman, Bali Pulendran, Mehul S Suthar

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Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis. حسب Amelia K Pinto, Hilario J Ramos, Xiaobo Wu, Shilpa Aggarwal, Bimmi Shrestha, Matthew Gorman, Kristin Y Kim, Mehul S Suthar, John P Atkinson, Michael Gale, Michael S Diamond

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IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection. حسب Hilario J Ramos, Marion C Lanteri, Gabriele Blahnik, Amina Negash, Mehul S Suthar, Margaret M Brassil, Khushbu Sodhi, Piper M Treuting, Michael P Busch, Philip J Norris, Michael Gale

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IPS-1 is essential for the control of West Nile virus infection and immunity. حسب Mehul S Suthar, Daphne Y Ma, Sunil Thomas, Jennifer M Lund, Nu Zhang, Stephane Daffis, Alexander Y Rudensky, Michael J Bevan, Edward A Clark, Murali-Krishna Kaja, Michael S Diamond, Michael Gale

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The amphibian peptide Yodha is virucidal for Zika and dengue viruses حسب Song Hee Lee, Eui Ho Kim, Justin T. O’neal, Gordon Dale, David J. Holthausen, James R. Bowen, Kendra M. Quicke, Ioanna Skountzou, Shyla Gopal, Sanil George, Jens Wrammert, Mehul S. Suthar, Joshy Jacob

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SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity حسب Lizhou Zhang, Cody B. Jackson, Huihui Mou, Amrita Ojha, Haiyong Peng, Brian D. Quinlan, Erumbi S. Rangarajan, Andi Pan, Abigail Vanderheiden, Mehul S. Suthar, Wenhui Li, Tina Izard, Christoph Rader, Michael Farzan, Hyeryun Choe

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