Can T Cells Abort SARS-CoV-2 and Other Viral Infections? Dahkki Leo Swadling, Mala K. Maini

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Immunotherapy for hepatocellular carcinomaKey points Dahkki Alexa Childs, Gloryanne Aidoo-Micah, Mala K. Maini, Tim Meyer

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Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection Dahkki Dimitra Peppa, Dimitra Peppa, Dimitra Peppa, Isabela Pedroza-Pacheco, Pierre Pellegrino, Ian Williams, Mala K. Maini, Persephone Borrow

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Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo. Dahkki Upkar S Gill, Dimitra Peppa, Lorenzo Micco, Harsimran D Singh, Ivana Carey, Graham R Foster, Mala K Maini, Patrick T F Kennedy

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ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome Dahkki Nicholas J. W. Easom, Nicholas J. W. Easom, Michael Marks, Dawda Jobe, Roopinder Gillmore, Tim Meyer, Tim Meyer, Mala K. Maini, Ramou Njie

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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells. Dahkki Anna Schurich, Laura J Pallett, Marcin Lubowiecki, Harsimran D Singh, Upkar S Gill, Patrick T Kennedy, Eleni Nastouli, Sudeep Tanwar, William Rosenberg, Mala K Maini

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CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity Dahkki Roland Preece, Andrea Pavesi, Soragia Athina Gkazi, Kerstin A. Stegmann, Christos Georgiadis, Zhi Ming Tan, Jia Ying Joey Aw, Mala K. Maini, Antonio Bertoletti, Waseem Qasim

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Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. Dahkki Gaia Nebbia, Dimitra Peppa, Anna Schurich, Pooja Khanna, Harsimran D Singh, Yang Cheng, William Rosenberg, Geoffrey Dusheiko, Richard Gilson, Joanne ChinAleong, Patrick Kennedy, Mala K Maini

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Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection. Dahkki Dimitra Peppa, Lorenzo Micco, Alia Javaid, Patrick T F Kennedy, Anna Schurich, Claire Dunn, Celeste Pallant, Gidon Ellis, Pooja Khanna, Geoffrey Dusheiko, Richard J Gilson, Mala K Maini

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The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV Dahkki Senthil K. Chinnakannan, Tamsin N. Cargill, Timothy A. Donnison, M. Azim Ansari, Sarah Sebastian, Lian Ni Lee, Claire Hutchings, Paul Klenerman, Mala K. Maini, Tom Evans, Eleanor Barnes

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Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host Dahkki Anna Schurich, Laura J. Pallett, Danyal Jajbhay, Jessica Wijngaarden, Itziar Otano, Upkar S. Gill, Navjyot Hansi, Patrick T. Kennedy, Eleni Nastouli, Richard Gilson, Christian Frezza, Sian M. Henson, Mala K. Maini

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Licensing virus-specific T cells to secrete the neutrophil attracting chemokine CXCL-8 during hepatitis B virus infection. Dahkki Adam J Gehring, Sarene Koh, Adeline Chia, Komathi Paramasivam, Valerie Suk Peng Chew, Zi Zong Ho, Kang Hoe Lee, Mala K Maini, Krishnakumar Madhavan, Seng Gee Lim, Antonio Bertoletti

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Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma Dahkki Nekisa Zakeri, Andrew Hall, Leo Swadling, Laura J. Pallett, Nathalie M. Schmidt, Mariana O. Diniz, Stephanie Kucykowicz, Oliver E. Amin, Amir Gander, Massimo Pinzani, Brian R. Davidson, Alberto Quaglia, Mala K. Maini

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IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction Dahkki Nicholas J. W. Easom, Kerstin A. Stegmann, Leo Swadling, Laura J. Pallett, Alice R. Burton, Dennis Odera, Nathalie Schmidt, Wei-Chen Huang, Wei-Chen Huang, Giuseppe Fusai, Brian Davidson, Mala K. Maini

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TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis Dahkki Harsimran D. Singh, Itziar Otano, Krista Rombouts, Kasha P. Singh, Dimitra Peppa, Upkar S. Gill, Katrin Böttcher, Patrick T. F. Kennedy, Jude Oben, Massimo Pinzani, Henning Walczak, Giuseppe Fusai, William M. C. Rosenberg, Mala K. Maini

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Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry Dahkki Stephanie Kucykowicz, Oliver E. Amin, Alice R. Burton, Leo Swadling, Nathalie M. Schmidt, Nekisa Zakeri, Jessica Davies, Gloryanne Aidoo-Micah, Kerstin A. Stegmann, Nicholas J. Easom, Anna Jeffery-Smith, Mala K. Maini, Laura J. Pallett

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SARS-CoV-2–specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies Dahkki Anna Jeffery-Smith, Alice R. Burton, Sabela Lens, Chloe Rees-Spear, Jessica Davies, Monika Patel, Robin Gopal, Luke Muir, Felicity Aiano, Katie J. Doores, J. Yimmy Chow, Shamez N. Ladhani, Maria Zambon, Laura E. McCoy, Mala K. Maini

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Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity Dahkki Daniel M. Altmann, Catherine J. Reynolds, George Joy, Ashley D. Otter, Joseph M. Gibbons, Corinna Pade, Leo Swadling, Mala K. Maini, Tim Brooks, Amanda Semper, Áine McKnight, Mahdad Noursadeghi, Charlotte Manisty, Thomas A. Treibel, James C. Moon, COVIDsortium investigators, Rosemary J. Boyton

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Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence Dahkki Leo Swadling, Laura J. Pallett, Mariana O. Diniz, Josephine M. Baker, Oliver E. Amin, Kerstin A. Stegmann, Alice R. Burton, Nathalie M. Schmidt, Anna Jeffery-Smith, Nekisa Zakeri, Kornelija Suveizdyte, Farid Froghi, Giuseppe Fusai, William M. Rosenberg, Brian R. Davidson, Anna Schurich, A. Katharina Simon, Mala K. Maini

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Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination Dahkki Elena Mitsi, Mariana O. Diniz, Jesús Reiné, Andrea M. Collins, Ryan E. Robinson, Angela Hyder-Wright, Madlen Farrar, Konstantinos Liatsikos, Josh Hamilton, Onyia Onyema, Britta C. Urban, Carla Solórzano, Sandra Belij-Rammerstorfer, Emma Sheehan, Teresa Lambe, Simon J. Draper, Daniela Weiskopf, Alessandro Sette, Mala K. Maini, Daniela M. Ferreira

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