Role of Mitochondria in the Mechanism(s) of Action of Metformin מאת Guillaume Vial, Guillaume Vial, Dominique Detaille, Bruno Guigas

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Editorial: Immune Regulation of Metabolic Homeostasis מאת Bruno Guigas, Tony Jourdan, Rinke Stienstra, Rinke Stienstra

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Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes מאת Saurabh Vig, Joost M. Lambooij, Joost M. Lambooij, Arnaud Zaldumbide, Bruno Guigas

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The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation מאת Hendrik J. P. van der Zande, Dominik Nitsche, Laura Schlautmann, Bruno Guigas, Sven Burgdorf

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Cryopreservation of Human Hepatocytes Alters the Mitochondrial Respiratory Chain Complex 1 מאת Xavier Stéphenne, Mustapha Najimi, Dung Khuu Ngoc, Françoise Smets, Louis Hue, Bruno Guigas, Etienne M. Sokal

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ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis מאת Saurabh Vig, Joost M. Lambooij, Joost M. Lambooij, Mette C. Dekkers, Frank Otto, Françoise Carlotti, Bruno Guigas, Arnaud Zaldumbide

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Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance. מאת Lisa R Hoving, Hendrik J P van der Zande, Amanda Pronk, Bruno Guigas, Ko Willems van Dijk, Vanessa van Harmelen

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Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation מאת Marie Octave, Laurence Pirotton, Audrey Ginion, Valentine Robaux, Sophie Lepropre, Jérôme Ambroise, Caroline Bouzin, Bruno Guigas, Martin Giera, Marc Foretz, Luc Bertrand, Christophe Beauloye, Sandrine Horman

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Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis מאת Pascale Gluais‐Dagorn, Marc Foretz, Gregory R. Steinberg, Battsetseg Batchuluun, Anna Zawistowska‐Deniziak, Joost M. Lambooij, Bruno Guigas, David Carling, Pierre‐Axel Monternier, David E. Moller, Sebastien Bolze, Sophie Hallakou‐Bozec

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Extracellular vesicles derived from stressed beta cells mediate monocyte activation and contribute to islet inflammation מאת Mette C. Dekkers, Joost M. Lambooij, Joost M. Lambooij, Xudong Pu, Raphael R. Fagundes, Agustin Enciso-Martinez, Agustin Enciso-Martinez, Agustin Enciso-Martinez, Kim Kats, Ben N. G. Giepmans, Bruno Guigas, Arnaud Zaldumbide

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Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice מאת Claudia P. Coomans, Janine J. Geerling, Bruno Guigas, Anita M. van den Hoek, Edwin T. Parlevliet, D. Margriet Ouwens, Hanno Pijl, Peter J. Voshol, Patrick C.N. Rensen, Louis M. Havekes, Johannes A. Romijn

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Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption מאת Cédric Langhi, Marie Vallier, Yolanda F. Otero, Maheva Maura, Florian Le Joubioux, Hugo Groult, Oussama Achour, Ratna Budhi Pebriana, Martin Giera, Bruno Guigas, Thierry Maugard, Benoit Chassaing, Sébastien Peltier, Jean-Marie Bard, Pascal Sirvent

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Dendritic cell–intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity מאת Hendrik J.P. vanderZande, Eline C. Brombacher, Joost M. Lambooij, Leonard R. Pelgrom, Anna Zawistowska-Deniziak, Thiago A. Patente, Graham A. Heieis, Frank Otto, Arifa Ozir-Fazalalikhan, Maria Yazdanbakhsh, Bart Everts, Bruno Guigas

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A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice מאת Cédric Langhi, Marie Vallier, Auriane Bron, Yolanda F. Otero, Maheva Maura, Florian Le Joubioux, Niek Blomberg, Martin Giera, Bruno Guigas, Thierry Maugard, Benoit Chassaing, Sébastien Peltier, Stéphanie Blanquet-Diot, Jean-Marie Bard, Pascal Sirvent

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Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice[S] מאת Janna A. van Diepen, Man C. Wong, Bruno Guigas, Jasper Bos, Rinke Stienstra, Leanne Hodson, Steven E. Shoelson, Jimmy F.P. Berbée, Patrick C.N. Rensen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol

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Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP miceResearch in context מאת Zhixiong Ying, Robin van Eenige, Xiaoke Ge, Christy van Marwijk, Joost M. Lambooij, Bruno Guigas, Martin Giera, Jan Freark de Boer, Tamer Coskun, Hongchang Qu, Yanan Wang, Mariëtte R. Boon, Patrick C.N. Rensen, Sander Kooijman

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Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity. מאת Aprilianto E Wiria, Firdaus Hamid, Linda J Wammes, Margaretta A Prasetyani, Olaf M Dekkers, Linda May, Maria M M Kaisar, Jaco J Verweij, Bruno Guigas, Felix Partono, Erliyani Sartono, Taniawati Supali, Maria Yazdanbakhsh, Johannes W A Smit

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Correction: Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity. מאת Aprilianto E Wiria, Firdaus Hamid, Linda J Wammes, Margaretta A Prasetyani, Olaf M Dekkers, Linda May, Maria M M Kaisar, Jaco J Verweij, Bruno Guigas, Felix Partono, Erliyani Sartono, Taniawati Supali, Maria Yazdanbakhsh, Johannes W A Smit

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DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice מאת Xiaoke Ge, Bram Slütter, Joost M. Lambooij, Enchen Zhou, Zhixiong Ying, Ceren Agirman, Marieke Heijink, Antoine Rimbert, Bruno Guigas, Johan Kuiper, Christoph Müller, Franz Bracher, Martin Giera, Sander Kooijman, Patrick C.N. Rensen, Yanan Wang, Milena Schönke

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Fasciola hepatica Fatty Acid Binding Protein 1 Modulates T cell Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic Homeostasis in Obese... מאת Anna Zawistowska-Deniziak, Anna Zawistowska-Deniziak, Anna Zawistowska-Deniziak, Joost M. Lambooij, Joost M. Lambooij, Alicja Kalinowska, Thiago A. Patente, Thiago A. Patente, Maciej Łapiński, Hendrik J. P. van der Zande, Hendrik J. P. van der Zande, Katarzyna Basałaj, Clarize M. de Korne, Clarize M. de Korne, Clarize M. de Korne, Mathilde A. M. Chayé, Mathilde A. M. Chayé, Thomas A. Gasan, Thomas A. Gasan, Luke J. Norbury, Luke J. Norbury, Martin Giera, Arnaud Zaldumbide, Hermelijn H. Smits, Hermelijn H. Smits, Bruno Guigas, Bruno Guigas

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